Hypophosphatasia with Coexisting Endocrinopathies: A Diagnostic Dilemma [0.03%]
合并内分泌疾病的低磷血症性佝偻病的诊断困境
Anil K Chokkalla,Niyutchai Chaithongdi,Megan Bell
Anil K Chokkalla
Adult-onset hypophosphatasia presents a diagnostic challenge due to confounding clinical and analytical factors. Although rare, the consequence of missed diagnosis is significant, as it can potentiate skeletal mineralization defects. Despit...
Case Reports
EJIFCC. 2026 Mar 30;37(2):379-382. DOI: 2026
Beneficial Intelligence in Laboratory Medicine: Aligning Human and Artificial Intelligence for Value-Based Outcomes [0.03%]
实验室医学中的有益智能：以人为本， aligning human和人工智能以实现基于价值的结果
Damien Gruson,Pradeep Kumar Dabla
Damien Gruson
The integration of artificial intelligence (AI) into healthcare and laboratory medicine is reshaping diagnostics, workflows, and patient management. Yet, technological progress alone cannot ensure meaningful outcomes. The concept of Benefic...
An optimized method for setting Internal Quality Control targets (mean and limits) for multi-instrument Internal Quality Control strategies in hematology? [0.03%]
血细胞分析多机质控目标值（平均数和界限值）设定的优化方法探究
Tony Badrick,Mathieu Bernard,Lionel Tabard et al.
Tony Badrick et al.
Objectives: Internal Quality Control (IQC) procedures must evolve as laboratory practices change to meet the requirements of higher patient volumes and the greater need for comparability of results across laboratories. Th...
Clinicians' Perspectives on the Impact of a Ransomware Attack on a Chemical Pathology Laboratory at a Tertiary Hospital in South Africa [0.03%]
南非三级医院临床医生对化学病理实验室遭遇勒索软件攻击影响的视角
Ameerah Davids,Aaqilah Fataar,Asande Zama et al.
Ameerah Davids et al.
Objectives: This study aimed to explore clinicians' experiences during a ransomware attack at a public academic hospital in South Africa and assess the perceived impact of chemical pathology laboratory service disruptions...
A Mini-Review of Point-of-Care C-Reactive Protein Testing in Sepsis in the Emergency Department [0.03%]
急诊科中关于脓毒症的床旁C-反应蛋白检测的小综述
Natasha Gomes Berlouis
Natasha Gomes Berlouis
Timely initiation of appropriate treatment of sepsis in the Emergency Department is crucial in a patient's prognosis. Surviving Sepsis Campaign guidelines suggest improved results in septic shock where antimicrobials are given within 1 hour...
Review
EJIFCC. 2026 Mar 30;37(2):260-267. DOI: 2026
Laboratory Professionals' Perspectives on Artificial Intelligence in Laboratory Medicine: Insights from a National Survey in Albania [0.03%]
人工智能在实验室医学中的作用：阿尔巴尼亚全国调查的见解
Helena Lame,Nevila Heta,Valbona Tole et al.
Helena Lame et al.
Introduction: While Artificial Intelligence (AI) is transforming Laboratory Medicine, successful AI integration depends on the readiness of healthcare professionals. This study aimed to assess the perspectives of Albanian...
Comparison of LDL-C Estimation Using Ridge Regression and Four Established Equations Against Direct Determination of LDL-C in a Northeastern Population in Thailand [0.03%]
泰国东北部人群血清低密度脂蛋白胆固醇直接测定与四种估计公式的比较研究 ridge 回归法初步探索
Sirawich Sonsok,Pongdech Sarakarn
Sirawich Sonsok
Background: Equations traditionally used for estimating low-density lipoprotein cholesterol (LDL-C) have limitations in accuracy and reliability. This study aimed to compare the performance of established equations with a...
Circulating netrin-1 levels in type 2 diabetes mellitus: A systematic review and meta-analysis [0.03%]
2型糖尿病中循环netrin-1水平系统评价和.meta.-分析
Roshan Kumar Mahat,Vedika Rathore,Mritunjay Kumar Mishra
Roshan Kumar Mahat
Background: Netrin-1, a laminin-related guidance cue protein with emerging immunomodulatory roles, has shown conflicting associations with type 2 diabetes mellitus (T2DM) in human studies. We conducted a systematic review...
Review
EJIFCC. 2026 Mar 30;37(2):345-363. DOI: 2026
Ulcerative colitis initially misdiagnosed as irritable bowel syndrome: A case report [0.03%]
误诊为肠易激综合征的溃疡性结肠炎病例报告
Swathi Nalla,Burra Sai Ruthvik,G Tulja Rani et al.
Swathi Nalla et al.
Background: Irritable bowel syndrome (IBS) and early ulcerative colitis (UC) share overlapping gastrointestinal symptoms, which may lead to misdiagnosis and delay in appropriate treatment. ...
Case Reports
EJIFCC. 2026 Mar 30;37(2):372-378. DOI: 2026
Plasma Gasdermin D as a Biomarker for Pyroptosis in Early Detection of Newly Diagnosed Type 2 Diabetes Mellitus [0.03%]
血浆Gasdermin D作为吡啶酰胺早期诊断2型糖尿病的生物标志物
Mimoh Sharma,Anil Kumar,Akash Garwal
Mimoh Sharma
Pyroptosis, a caspase-mediated inflammatory cell death pathway driven by Gasdermin D (GSDMD), has emerged as a potential mechanistic link between metabolic stress, β-cell injury, and chronic inflammation in Type 2 diabetes mellitus (T2DM)....