Punit Saraon,Andrei P Drabovich,Keith A Jarvi et al.
Punit Saraon et al.
Prostate cancer is the second leading cause of cancer-related deaths among men in North America. Almost all prostate cancers begin in an androgen-dependent state, so androgen deprivation therapy is administered and results in improved clini...
Genetic and Epigenetic Changes After Spermatogonial Stem Cell Culture and Transplantation [0.03%]
spermatogonial干细胞体外培养和移植后的基因和表观遗传改变
Mary K Samplaski,Marie Deault-Bonin,Kirk C Lo
Mary K Samplaski
Men with testicular failure, either primary or secondary, have been shown to be interested in fertility preservation. Spermatogonial stem cell (SSC) transplantation is currently being investigated as a treatment for this. Currently this exp...
An Emerging Role of TEX101 Protein as a Male Infertility Biomarker [0.03%]
TEX101蛋白作为男性不育生物标志物的作用机制研究
Christina G Schiza,Keith Jarv,Eleftherios P Diamandis et al.
Christina G Schiza et al.
Infertility is an important aspect of human reproduction. It affects up to 15% of couples, with the male factor contributing to approximately 50% of all cases. Azoospermia is one of the most severe forms of male infertility, which is charac...
Iron Indices in Patients with Functional Anemia in Chronic Kidney Disease [0.03%]
慢性肾脏病功能性贫血患者的铁指标状况研究
G Chinnapu Reddy,Ramakrishna Devaki,Pragna Rao
G Chinnapu Reddy
Background: Despite high ferritin level, HDCKD patients may have functional iron deficiency even after intravenous iron (iv) therapy. The aim of this study was to test the hypothesis that lowered serum transferrin level m...
Xavier Fuentes-Arderiu
Xavier Fuentes-Arderiu
The Advance of Personalized and Stratified Therapies in Bronchial Asthma: Phenotypes - Endotypes - Biomarkers [0.03%]
支气管哮喘的精准化治疗进展：表型-内型-生物标志物
Sebastian Lauer,Harald Renz
Sebastian Lauer
Bronchial asthma (BA) is a chronic inflammatory condition with increasing incidence and prevalence worldwide. BA is currently the most prevalent chronic disease in pediatric patients. The majority of BA patients are therapeutically well con...
Ron Hn van Schaik;IFCC Task Force on Pharmacogenetics: Prof. Dr. Maurizio Ferrari (IT), Prof. Dr. Michael Neumaier (GER), Prof. Dr. Munir Pirmohamed (UK) et al.
Ron Hn van Schaik;IFCC Task Force on Pharmacogenetics: Prof. Dr. Maurizio Ferrari (IT) et al.
Pharmacogenetic (PGx) testing has the potential to improve drug therapy in an individual by informing appropriate drug dosing or drug selection in order to maximize efficacy and safety. Although multiple studies have illustrated the potenti...
Cerebrospinal Fluid Biomarkers for Alzheimer's Disease: Emergence of the Solution to an Important Unmet Need [0.03%]
阿尔茨海默病脑脊液生物标志物：重要需求的解决方案的出现
C E Teunissen,Eaj Willemse
C E Teunissen
Alzheimer's Disease (AD) represents an increasing problem as the overall population ages. The identification of reliable biomarkers of AD has, therefore, become increasingly important. This is not only for risk prediction and diagnosis in o...
Ekaterina Lenk,Michael Spannagl
Ekaterina Lenk
Cardiovascular diseases are the leading cause of death in the Western world. Several factors have led to the increase in vascular disorders, including the aging population, unhealthy lifestyles, increasing rates of diabetes and raised lipid...