Surrogate Biomarkers for Monitoring Healthcare Quality for Chronic Diseases Such as Diabetes Care [0.03%]
用于监测慢性病（如糖尿病）护理质量的替代生物标志物
Diler Aslan
Diler Aslan
Some laboratory tests or biomarkers are used as surrogate outcomes for health care effectiveness. HbA1c is defined as a surrogate biomarker since HbA1c values have been approved to be used in predictions of clinically important complication...
Review
EJIFCC. 2018 Dec 5;29(4):303-308. DOI: 2018
Renata Paleari,Andrea Mosca
Renata Paleari
Background: A project for the standardization of HbA2 was launched by the IFCC back in 2004. Materials and methods: In this work we rep...
Review
EJIFCC. 2018 Dec 5;29(4):298-302. DOI: 2018
Urinary Proteomics in Biomarker Discovery of Kidney-Related Disorders: Diabetic Nephropathy and Drug-Induced Nephrotoxicity in Chronic Headache [0.03%]
尿蛋白组学在肾脏疾病生物标志物发现中的应用：糖尿病肾病和慢性头痛所致药物性肾毒性的研究
Elisa Bellei,Emanuela Monari,Stefania Bergamini et al.
Elisa Bellei et al.
Objective: Urinary proteomics is primarily applied to the study of renal and urogenital tract disorders. Here are reported two distinct successful examples of this approach for the discovery of early urinary biomarkers of...
Alcohol Abuse [0.03%]
酒精滥用
Tomáš Zima
Tomáš Zima
Chronic alcohol consumption is a world-wide socioeconomic problem. Three metabolic pathways of ethanol were describe in human - alcohol dehydrogenase (ADH), microsomal ethanol oxidizing system (MEOS, CYP2E1) and catalase. Ethanol directly b...
Adnan Alkhatib
Adnan Alkhatib
Pregnancy produces profound physiological changes that increase in significance as it progresses. These changes include hormonal changes, metabolic changes, increases of plasma volume up to 50%, alterations to the balance of the coagulation...
Prenatal Screening for Chromosomal Abnormalities: Where do We Stand Today in Mediterranean Countries? [0.03%]
地中海国家的产前筛查：我们目前处于什么位置？
Demetrios Rizos
Demetrios Rizos
Over the last 4 decades the practice of prenatal screening has evolved from the second-trimester triple test to complex combinations of biophysical and biochemical testing for aneuploidy, testing of fetal DNA in the maternal circulation and...
Review
EJIFCC. 2018 Dec 5;29(4):274-279. DOI: 2018
Which Skills are Needed and How They Should be Gained by Laboratory Medicine Professionals for Successful ISO 15189 Accreditation [0.03%]
实验室医学专业人员所需能力及其获取途径以成功通过ISO 15189认证
Diler Aslan
Diler Aslan
Clinical laboratories worldwide are accredited according to the "ISO standard, 15189:2012: Medical Laboratories-Requirements for Quality and Competence." Seeking accreditation has many challenges. Success requires the right competencies and...
Review
EJIFCC. 2018 Dec 5;29(4):264-273. DOI: 2018
An Evidence-Based Laboratory Medicine Approach to Evaluate New Laboratory Tests [0.03%]
基于证据的实验室医学方法评估新的实验室检测项目
Tommaso Trenti
Tommaso Trenti
The evidence-based recommendations for the evaluation of new tests to be used in practice are a key issue to improve diagnostic clinical pathway inducing effective care. Emerging precision or personalized medicine requires innovative and pi...
Review
EJIFCC. 2018 Dec 5;29(4):259-263. DOI: 2018
Alexander Haliassos
Alexander Haliassos
The role of Proficiency Testing schemes (PT) or External Quality Control programs (EQA), involves the use of inter-laboratory comparisons for the determination of laboratory performance. EQA-PT schemes are of primordial importance to the an...
Rania Abu Seir,Osama Najjar
Rania Abu Seir
Background: Laboratory Medicine (LM) is one of the cornerstones of healthcare. In Palestine, 3.5% of health expenditure is allocated to clinical laboratories. ...