Continuous Post-Market Sequential Safety Surveillance with Minimum Events to Signal [0.03%]
最小信号事件的连续上市后安全监测
Martin Kulldorff,Ivair R Silva
Martin Kulldorff
The CDC Vaccine Safety Datalink project has pioneered the use of near real-time post-market vaccine safety surveillance for the rapid detection of adverse events. Doing weekly analyses, continuous sequential methods are used, allowing inves...
Armando Teixeira-Pinto,Sharon-Lise Normand
Armando Teixeira-Pinto
Biomedical research often involves the measurement of multiple outcomes in different scales (continuous, binary and ordinal). A common approach for the analysis of such data is to ignore the potential correlation among the outcomes and mode...