Prediction of early responses to dupilumab treatment in patients with moderate-to-severe atopic dermatitis by a machine learning model integrating clinical characteristics and serum biomarkers [0.03%]
基于临床特征和血清生物标志物的机器学习模型预测中重度特应性皮炎患者杜匹鲁单抗治疗早期反应
Hong Huang,Mengdi Xu,Weijia Zhao
Hong Huang
Aim: The aim of the study was to evaluate the predictive value of baseline serum periostin and other T helper cell type 2 (Th2)-related biomarkers for early response to dupilumab in patients with moderate-to-severe atopic...
A monocentric retrospective real-world study from North Poland of dupilumab in adults and paediatric patients with atopic dermatitis: efficacy, safety, and dupilumab-associated hypereosinophilia [0.03%]
波兰北部成人及儿童特应性皮炎患者Dupixent单中心回顾性真实世界研究：疗效、安全性以及Dupixent相关性嗜酸性粒细胞增多症
Weronika Zysk,Magdalena Trzeciak,Aleksandra Wilkowska et al.
Weronika Zysk et al.
Introduction: Long-term real-life data on the efficacy of dupilumab in atopic dermatitis (AD) patients, especially within the paediatric population, are limited. ...
Management of paediatric anaphylaxis: evaluation of clinical practice according to the 2024 Polish Paediatric Society guidelines [0.03%]
儿科过敏性休克的管理：根据2024年波兰儿科协会指南评估临床实践
Jadwiga Biela-Mazur,Kamila Danecka-Baran,Marcelina Żola et al.
Jadwiga Biela-Mazur et al.
Introduction: Anaphylaxis is a severe, rapidly progressing allergic reaction that can be life-threatening. It may involve the skin and mucous membranes, as well as the respiratory, cardiovascular, or gastrointestinal syst...
Fractional CO2 laser augmented by polynucleotide and exosome-mimetic nanovesicles in atrophic acne scars: randomised comparative trial [0.03%]
聚核苷酸和外泌体模拟纳米囊增强的分数二氧化碳激光治疗萎缩性痤疮疤痕：随机对照试验
Rena Raad Helmi,Rusul Sahib Hussien Mohammed,Wassan Nori
Rena Raad Helmi
Introduction: Atrophic acne scars impose a significant physical and psychological burden. Fractional CO2 laser treatment is hindered by delayed healing and pigmentation. Exosome-mimetic nanovesicles (EMNV) may optimise ou...
Targeting macrophage function with botulinum toxin: a novel translational strategy for preventing and treating pathological scars [0.03%]
利用肉毒杆菌毒素靶向巨噬细胞功能：预防和治疗病理性瘢痕的新型转化策略
Ali Mohyeddin,Fazhi Qi
Ali Mohyeddin
Pathological scars, including hypertrophic scars and keloids, remain a significant clinical challenge due to the limitations of current treatments. Botulinum neurotoxin type A (BTX-A) has emerged as a transformative therapy, but its efficac...
Natural rubber latex allergy: causes, symptoms, and modern diagnostic methods [0.03%]
天然橡胶乳胶过敏：原因、症状及现代诊断方法
Maria Zofia Lisiecka,Joanna Luczak
Maria Zofia Lisiecka
Introduction: Natural latex allergy poses significant risks in medicine due to widespread use of the material and potential for severe reactions. Aim: ...
Life satisfaction among people with vitiligo: the role of social support and acceptance of the condition [0.03%]
白癜风患者的幸福感：社会支持和接受度的作用
Izabela Sowińska,Klaudia Dubis,Sylwia Kocur et al.
Izabela Sowińska et al.
Introduction: Vitiligo is a chronic skin condition characterised by progressive depigmentation. The visibility of skin lesions, their location, and perceived social stigma can exacerbate emotional stress and reduce life s...
Drug reaction with eosinophilia and systemic symptoms or peripheral T-cell lymphoma? That is the question [0.03%]
药物反应合并嗜酸性粒细胞增多和全身症状还是外周T细胞淋巴瘤？这是一个问题
Małgorzata Grabarczyk,Ryszard Swoboda,Katarzyna Michalak et al.
Małgorzata Grabarczyk et al.
20-MHz high-intensity focused ultrasound for seborrheic keratoses of the head and neck: outcomes and dermoscopic predictors [0.03%]
20兆赫高强度聚焦超声治疗头颈部脂溢性角化病的疗效及皮肤镜预测指标
Bartosz Woźniak,Piotr Giedziun,Karolina Gowans et al.
Bartosz Woźniak et al.
Introduction: Seborrheic keratoses (SKs) are common benign epidermal tumours that frequently require removal for cosmetic reasons and are located on the head and neck. Conventional destructive methods may cause scarring o...
TRAF3IP2 (rs13190932) polymorphism in psoriasis and psoriatic arthritis: susceptibility, systemic inflammation and response to methotrexate [0.03%]
TRAFFIC网络相关蛋白3互作蛋白2基因多态性与银屑病和银屑病关节炎的易感性、全身炎症及甲氨蝶呤治疗反应关系的研究
Eisa M Hegazy,Moustafa A El Taieb,Mohammed H Hassan et al.
Eisa M Hegazy et al.
Introduction: Psoriasis and psoriatic arthritis (PsA) are chronic immune-mediated inflammatory disorders. The TRAF3IP2 gene encodes Act1, a crucial adaptor protein in interleukin-17 signalling, which is fundamental to the...