C-Mannosylated tryptophan-containing WSPW peptide binds to actinin-4 and alters E-cadherin subcellular localization in lung epithelial-like A549 cells [0.03%]
含有C-岩藻糖基化色氨酸的WSPW肽与actinin-4结合并改变肺类上皮A549细胞中E-钙粘着蛋白的亚细胞定位
Midori Ikezaki,Kazuchika Nishitsuji,Ko Matsumura et al.
Midori Ikezaki et al.
The Trp-x-x-Trp (W-x-x-W) peptide motif, a consensus site for C-mannosylation, is the functional motif in cytokine type I receptors or thrombospondin type I repeat (TSR) superfamily proteins. W-x-x-W motifs are important for physiological a...
Intraspecific venom variation of Mexican West Coast Rattlesnakes (Crotalus basiliscus) and its implications for antivenom production [0.03%]
墨西哥西海岸响尾蛇(Crotalus basiliscus)的种内毒液变异及其对抗蛇毒血清生产的意义
Andrea Colis-Torres,Edgar Neri-Castro,Jason L Strickland et al.
Andrea Colis-Torres et al.
Intraspecific variation in snake venoms has been widely documented worldwide. However, there are few studies on this subject in Mexico. Venom characterization studies provide important data used to predict clinical syndromes, to evaluate th...
Thymoquinone provides structural protection of human hemoglobin against oxidative damage: Biochemical studies [0.03%]
姜原醌对人血红蛋白的结构保护作用以防止氧化损伤：生化研究
Zafar Rasheed,Adel Alharbi,Abdullah Alrakebeh et al.
Zafar Rasheed et al.
Hydroxyl radicals (OH.) are one of the most active reactive oxidants recognized for their deleterious effects to cause protein oxidative damage. Thymoquinone, a monoterpene molecule abundantly present in black cumin and known for its pharma...
Edclécia N Santos,Lorenna P Menezes,Silvio S Dolabella et al.
Edclécia N Santos et al.
Bacillus thuringiensis (Bt) is a ubiquitous bacterium that produces several proteins that are toxic to different invertebrates such as insects, nematodes, mites, and also some protozoans. Among these, Cry and Cyt proteins are most explored ...
Low expression of CD24 is associated with poor survival in colorectal cancer [0.03%]
CD24低表达与结直肠癌预后不良相关
Stepan Nersisyan,Ann-Kristin Ahlers,Tobias Lange et al.
Stepan Nersisyan et al.
In this study we analyzed expression of CD24 in a cohort of colorectal cancer patients using immunohistochemistry staining of CD24. We found a significant association between absence or low expression of CD24 (10% of membranous and 55% of c...
Structural and thermodynamic analyses of human TMED1 (p24γ1) Golgi dynamics [0.03%]
人类TMED1（p24γ1）高尔基体动态的结构和热力学分析
Danielly C A M Mota,Iara A Cardoso,Renan M Mori et al.
Danielly C A M Mota et al.
The transmembrane emp24 domain-containing (TMED) proteins, also called p24 proteins, are members of a family of sorting receptors present in all representatives of the Eukarya and abundantly present in all subcompartments of the early secre...
Prediction of lysine formylation sites using support vector machine based on the sample selection from majority classes and synthetic minority over-sampling techniques [0.03%]
基于多数类样本选择和合成少数类过采样技术的 SUPPORT VECTOR MACHINE 法预测赖氨酸戊糖基化位点
Md Sohrawordi,Md Ali Hossain
Md Sohrawordi
Lysine formylation is a newly discovered and mostly interested type of post-translational modification (PTM) that is generally found on core and linker histone proteins of prokaryote and eukaryote and plays various important roles on the re...
Biological evaluation and spectral characterization of a novel tetracenomycin X congener [0.03%]
新型四环霉素X同类物的生物评价和光谱特征分析
Vera A Alferova,Tinashe P Maviza,Mikhail V Biryukov et al.
Vera A Alferova et al.
The aromatic polyketide tetracenomycin X (TcmX) was recently found to be a potent inhibitor of protein synthesis; its binding site is located in a unique locus within the tunnel of the large ribosomal subunit. The distinct mode of action ma...
Spectroscopic and functional characterization of the [2Fe-2S] scaffold protein Nfu from Synechocystis PCC6803 [0.03%]
来自Synechocystis PCC6803的[2Fe-2S]支架蛋白Nfu的光谱和功能特征分析
Zechariah Thompson,Insiya Fidai,Christine Wachnowsky et al.
Zechariah Thompson et al.
Iron-sulfur clusters are ubiquitous cofactors required for various essential metabolic processes. Conservation of proteins required for their biosynthesis and trafficking allows for simple bacteria to be used as models to aid in exploring t...
Neurotoxic or neuroprotective: Post-translational modifications of α-synuclein at the cross-roads of functions [0.03%]
神经毒性或神经营护：α-突触核蛋白的翻译后修饰在其功能中的交汇点
Joshna Gadhavi,Mohini Patel,Dhiraj Bhatia et al.
Joshna Gadhavi et al.
Parkinson's disease is the second most prevalent neurodegenerative disease. The loss of dopaminergic neurons in the substantia nigra is one of the pathological hallmarks of PD. PD also belongs to the class of neurodegenerative disease known...