First-in-human EphA2-targeting PET imaging with the bicyclic radiotracer [68Ga]Ga-BCY18469 in pancreatic cancer patients: biodistribution, dosimetry and initial findings [0.03%]
针对胰腺癌患者的人体首次EphA2靶向PET成像研究：采用放射性示踪剂[68Ga]Ga-BCY18469的生物分布、剂量学及初步结果
Ann-Christin Eder,Christoph-Ferdinand Wielenberg,Mohamed Aymen Omrane et al.
Ann-Christin Eder et al.
Purpose: Erythropoietin-producing hepatocellular receptor A2 (EphA2) is overexpressed in various malignancies, including pancreatic ductal adenocarcinoma (PDAC), in which it correlates with poor prognosis. Although EphA2 ...
Identifing two distinct cortical progression subtypes of Parkinson's disease through multimodal neuroimaging [0.03%]
通过多模态神经影像识别帕金森病的两种不同的皮层进展亚型
Qinwei Yu,Xueyi Guan,Jinfeng Wu et al.
Qinwei Yu et al.
Purpose: To investigate whether distinct patterns of cortical involvement exist in Parkinson's disease (PD) and to characterize their potential progression trajectories using multimodal neuroimaging and data-driven diseas...
Chrónos and Káiros in theragnostics: re-assessing time toxicity in final-line radiopharmaceutical treatments [0.03%]
时间毒理学在终末期放射药物治疗中的再评估：论CHRONOS和KAIROS的影响
Ian Alberts,Christos Sachpekidis,Sandy Buchman
Ian Alberts
Justine Maes,Alex Maes,Kristoff Muylle et al.
Justine Maes et al.
A patient with metastasized prostate adenocarcinoma underwent 18F-PSMA-11 PET/CT restaging following 177Lu-PSMA-617 treatment and rising PSA-level. The maximum intensity projection image (right-side of the figure) demonstrated an intense ho...
PHYTO-PET - Imaging plant physiology on a long-axial field-of-view PET scanner [0.03%]
PHYTO-PET——在长轴视野的正电子发射断层扫描仪上成像植物生理学
Ian Alberts,Nadine Colpo,Caroline Williams et al.
Ian Alberts et al.
Aim: Non-human imaging using either inanimate phantoms or live animal models is sometimes performed as an alternative to human subjects but involve limitations either in fidelity for the former and ethical considerations ...
Assessing subcortical, brainstem and cerebellar metabolic patterns using [18F]FDG PET-CT imaging in dementia with Lewy bodies [0.03%]
使用[18F]FDG PET-CT成像评估Lewy体痴呆的纹状体、脑干和小脑代谢模式
Daniël S L Loewenstein,Max van Grinsven,Cécile de Pont et al.
Daniël S L Loewenstein et al.
Purpose: Numerous clinical features of Dementia with Lewy Bodies (DLB) are attributed to dysfunction in subcortical anatomy. Despite this, [18F]FDG PET imaging as a diagnostic tool for DLB largely relies on the metabolic ...
Clinical value of gated SPECT-derived left ventricular strain and reserve: derivation of quantitative cutoffs [0.03%]
门控SPECT衍生的左心室应变和储备的临床价值：定量截止值的确定
Guillermo Romero-Farina,Santiago Aguadé-Bruix,C David Cooke et al.
Guillermo Romero-Farina et al.
Purpose: This study aimed to assess interobserver reproducibility of left ventricular global longitudinal (LS), circumferential (CS), and radial (RS) myocardial strain measurements, to determine cutoff values including co...
Consolidative therapy for PSMA-avid lesions after 3 cycles of apalutamide plus androgen deprivation in metastatic hormone-sensitive prostate cancer: A prospective phase 2 single-arm trial [0.03%]
一项前瞻性单臂二期试验：3例接受阿帕鲁胺联合雄激素剥夺治疗后的转移性激素敏感性前列腺癌患者PSMA显像阳性病灶强化治疗效果评估
Jian Pan,Beihe Wang,Bin Zhu et al.
Jian Pan et al.
Background: Metastatic hormone-sensitive prostate cancer (mHSPC) with limited metastatic burden presents a therapeutic challenge, with residual PSMA-avid disease post-androgen receptor pathway inhibitor (ARPI) treatment p...
Mediastinal over-staging with PET-CT in tuberculosis-endemic locally advanced NSCLC: SUV threshold recalibration improves PET/EBUS concordance [0.03%]
PET-CT在肺结核高发地区晚期NSCLC中心脏淋巴结分期过度：调整SUV阈值可提高PET/EBUS一致性
Manoj Gupta,Irfan Ahmad,Kundan Singh Chufal et al.
Manoj Gupta et al.
Purpose: To quantify concordance between blinded PET-CT reinterpretation and EBUS-guided transbronchial needle aspiration (EBUS-TBNA) cytology for mediastinal lymph node staging in locally advanced NSCLC in a tuberculosis...
Real-world outcomes of [177Lu]Lu-PSMA-I&T in [18F]FDG-positive metastatic castration-resistant prostate cancer: factors related to response and survival [0.03%]
[177Lu]Lu-PSMA-I&T治疗的现实世界结局：影响疗效和生存的因素分析（来自中国5家医疗中心的数据）
Giulia Santo,Gianpaolo di Santo,Ariane Kronthaler et al.
Giulia Santo et al.
Background: Little is known about predictors of response to radionuclide therapy with PSMA-ligands in patients with [18F]FDG-positive metastatic castration-resistant prostate cancer (mCRPC). We assessed the correlation be...