A novel mWGA-TYR PET reporter gene system for in vivo visualization of whole brain-level neural circuit [0.03%]
一种新颖的mWGA-TYR PET报告基因系统用于整个脑水平神经环路的体内成像
Xiaoyun Luo,Chentao Jin,Yuanjie Chen et al.
Xiaoyun Luo et al.
Purpose: This study aimed to develop a novel PET reporter gene imaging system based on modified wheat germ agglutinin (mWGA) and tyrosinase (TYR) for tracing trans‑monosynaptic neural circuit in vivo. ...
Context-dependent efficacy of fibroblast activation protein-targeted radionuclide therapy (FAP-TRT): the dual role of CAFs [0.03%]
成纤维细胞活化蛋白靶向放射性核素治疗(FAP-TRT)的疗效依赖于肿瘤间质环境:癌症相关成纤维细胞的双重作用
Chunhui Wu,Ahmad Kurniawan,Ge Li et al.
Chunhui Wu et al.
Fibroblast activation protein-targeted radionuclide therapy (FAP-TRT) shows promise across multiple cancers, but clinical responses remain variable. Here, we aim to investigate how the presence, abundance, and spatial organisation of FAP-ex...
Prospective evaluation of the PRIMARY score using [18F]PSMA-1007 PET/MRI in second-line prostate biopsies after negative MRI [0.03%]
[18F]PSMA-1007-PET/MRI指导下的前列腺二次活检中PRIMARY评分的应用价值评估(首次MRI检查阴性)
Mads Ryø Jochumsen,Lise Medrud,André H Dias et al.
Mads Ryø Jochumsen et al.
Purpose: PSMA PET has been proposed for guiding targeted prostate biopsies. As the rate of clinically significant prostate cancer (csPCa) is positively correlated with PSA density (PSAd), a potential application for PSMA-...
Hidden risk in normal myocardial perfusion scans: AI-detected proximal coronary calcium on CT attenuation maps improves prognosis [0.03%]
正常心肌灌注扫描中的隐性风险:CT衰减图上的AI检测到的proximal冠脉钙化改善预后
Jianhang Zhou,Robert J H Miller,Aakash Shanbhag et al.
Jianhang Zhou et al.
Purpose: Spatial distribution of coronary artery calcium (CAC) may provide additional prognostic value in patients undergoing SPECT and PET myocardial perfusion imaging (MPI). We aimed to automatically identify CAC in pro...
Diagnostic performance of ¹⁸F-FDG PET/CT radiomics-based machine learning models for pancreatic lesion characterisation: Comparison with visual assessment and evaluation of human-radiomics synergy [0.03%]
基于18F-FDG PET/CT影像组学的机器学习模型在胰腺病变定性诊断效能:与视觉评估对比及探讨人机协同价值
Dilsat Firat Arslan,Zeynep Gozde Ozkan,Ali Bayram et al.
Dilsat Firat Arslan et al.
Purpose: We aimed to evaluate the diagnostic performance of ¹⁸F-FDG PET/CT-derived radiomics-based machine learning models for differentiating malignant from benign pancreatic lesions, to compare these models with two s...
The deep learning radiomics nomogram for risk stratification in multiple myeloma using automatic whole-body [18F]FDG PET/CT segmentation approach [0.03%]
基于自动全身[18F]FDG PET/CT分割的深度学习影像组学预测多发性骨髓瘤预后的列线图模型
Meiling Xiao,Yan Zhong,Han Hao et al.
Meiling Xiao et al.
Purpose: To develop a deep learning (DL) approach for automatic segmentation and accurate risk stratification in multiple myeloma (MM) using whole-body [18F]FDG PET/CT. ...
PET/CT-derived whole-body composition and survival in resectable NSCLC: double machine learning-based adjusted association analysis of intermuscular adiposity burden and sex-specific metabolic phenotypes [0.03%]
基于双机器学习的调整关联分析衍生出来的全身成分和可手术NSCLC患者的生存关系:骨骼肌内脂肪负担和性别特异性代谢表型的作用
Weihao Zhai,Ruoyao Wang,Mengmeng Ye et al.
Weihao Zhai et al.
Purpose: To evaluate whether whole-body PET/CT-derived body composition features are associated with survival in patients with resectable non-small cell lung cancer (NSCLC), using double machine learning to quantify adjus...
Standardized FDG-PET interpretation during CAR T-cell therapy in R/R DLBCL: a DESCAR-T study [0.03%]
抗CD19 CAR-T治疗复发/难治性弥漫大 B 细胞淋巴瘤期间 FDG-PET 标准化判读的描述性研究(DESCAR-T 研究)
Yassine Al Tabaa,Clément Bailly,Xavier Palard-Novello et al.
Yassine Al Tabaa et al.
Purpose: CAR T-cell therapy has changed the management of relapsed/refractory (R/R) Diffuse large B-cell lymphoma (DLBCL). Fluorodeoxyglucose Positron Emission Tomography Computed Tomography (PET/CT) plays a central role ...
From reflex to reason: rethinking pelvic lymph node dissection in the PSMA PET Era [0.03%]
从反射到理性:PSMA-PET时代的盆腔淋巴结清扫术再思考
Gamze Beydagi,Gianluca Giannarini,Alessandro Crestani et al.
Gamze Beydagi et al.
Pulmonary [18F]FDG uptake demonstrates phenotypic PET behaviour in non-specific interstitial pneumonitis and refines risk stratification [0.03%]
肺[18F]FDG摄取量在非特异性间质性肺炎中表现出表型PET行为并细化了风险分层
Hannah Torlot,Balaji Ganeshan,Thida Win et al.
Hannah Torlot et al.
Rationale: Effective prognostic biomarkers in Non-specific Interstitial Pneumonitis (NSIP) are limited. Objective: To investigate the p...