Design of a dual Ir-Eu tag for fluorescent visualization and ICP-MS quantification of SIRPα and its host cells [0.03%]
双Ir-Eu标签的设计用于SIRPα及其宿主细胞的荧光可视化和ICP-MS定量分析
Chunlan Liu,Pengtao Li,Xiaowen Yan et al.
Chunlan Liu et al.
With the expansion of ICP-MS application into the field of bioanalysis, there is an urgent need for novel element tags today. Here, we report the design of a dual-element Ir-Eu tag, opening the door to simultaneous fluorescent imaging and I...
Sensitive fluorescence ELISA for the detection of zearalenone based on self-assembly DNA nanocomposites and copper nanoclusters [0.03%]
基于自组装DNA纳米复合材料和铜纳米团簇的玉米赤霉烯酮敏感荧光ELISA检测方法
Xudong Jing,Sha Yu,Ganggang Zhang et al.
Xudong Jing et al.
Zearalenone (ZEN), produced by Fusarium species, is a potential risk to human health. Traditional enzyme-linked immunosorbent assay (ELISA) is restricted due to low sensitivity for the detection of ZEN. Herein, enzyme nanocomposites (ALP-SA...
Applying a risk assessment guided evaluation for verifying comprehensive two-dimensional gas chromatography to analyse complex pharmaceuticals [0.03%]
应用风险评估指引评价法验证综合二维气相色谱分析复杂药品
Lukas Schwalb,Ole Tiemann,Uwe Käfer et al.
Lukas Schwalb et al.
The reliability of analytical results is critical and indispensable when applied in regulated environments such as the pharmaceutical industry. Therefore, analytical workflows must be validated. However, validation guidelines are often desi...
Plant-based meat substitute analysis using microextraction with deep eutectic solvent followed by LC-MS/MS to determine acrylamide, 5-hydroxymethylfurfural and furaneol [0.03%]
使用深层共熔溶剂微萃取结合LC-MS/MS测定植物基肉类替代品中丙烯酰胺、5-羟甲基糠醛和呋喃酮的分析方法
Dominika Osiecka,Christina Vakh,Patrycja Makoś-Chełstowska et al.
Dominika Osiecka et al.
For the analysis of plant-based meat substitutes and the determination of Maillard reaction products such as acrylamide, 5-hydroxymethylfurfural and furaneol, a novel and effective procedure based on hydrophobic natural deep eutectic solven...
MNAzyme catalyzed signal amplification-mediated lateral flow biosensor for portable and sensitive detection of mycotoxin in food samples [0.03%]
一种用于食品样品中霉菌毒素便携、灵敏检测的MNAzyme催化信号放大免疫层析方法
Yan Yang,Yiheng Shi,Xianlong Zhang et al.
Yan Yang et al.
Here, an enzyme-free lateral flow aptasensor was designed by target-induced strand-displacement effect and followed by the activation of multi-component nucleic acid enzyme (MNAzyme)-mediated cleavage to enable rapid and portable ochratoxin...
Development of cancer biomarker heat shock protein 90α certified reference material using two different isotope dilution mass spectrometry techniques [0.03%]
基于两种同位素稀释质量测定技术的癌症生物标志物热休克蛋白90α标准物质研制与发展
Manman Zhu,Jingjing Li,Zhanying Chu et al.
Manman Zhu et al.
Heat shock protein 90α (HSP90α) has been regarded as an important indicator for judging tumor metastasis and prognosis due to its significant upregulation in various tumors. Therefore, the accurate quantification of HSP90α is of great si...
Optimisation of electrochemical sensors based on molecularly imprinted polymers: from OFAT to machine learning [0.03%]
基于分子印迹聚合物的电化学传感器优化：从单因子试验到机器学习
Sabrina Di Masi,Giuseppe Egidio De Benedetto,Cosimino Malitesta
Sabrina Di Masi
Molecularly imprinted polymers (MIPs) rely on synthetic engineered materials able to selectively bind and intimately recognise a target molecule through its size and functionalities. The way in which MIPs interact with their targets, and th...
Correction to: Enzyme‑targeted near‑infrared fluorescent probe for organophosphorus pesticide residue detection [0.03%]
Correction to: 用于有机磷农药残留检测的酶靶向近红外荧光探针
Shan Luo,Ruichen Peng,Ying Wang et al.
Shan Luo et al.
Published Erratum
Analytical and bioanalytical chemistry. 2024 Feb;416(5):1307. DOI:10.1007/s00216-023-05112-9 2024
Chris Weise,Hannes Westphal,Rico Warias et al.
Chris Weise et al.
Herein, we present a miniaturized chip-based HPLC approach coupled to electrospray ionization mass spectrometry utilizing temperature to achieve high-speed separations. The approach benefits from the low thermal mass of the microfluidic chi...
eCerto-versatile software for interlaboratory data evaluation and documentation during reference material production [0.03%]
eCerto-实验室间数据评估和参考材料生产过程中文件记录的多功能软件
Jan Lisec,Sebastian Recknagel,Carsten Prinz et al.
Jan Lisec et al.
The statistical tool eCerto was developed for the evaluation of measurement data to assign property values and associated uncertainties of reference materials. The analysis is based on collaborative studies of expert laboratories and was im...