Programmable DNA aptamer logic gates: from structural design to integrated systems for intelligent nanoscale biosensors [0.03%]
可编程的DNA适配子逻辑门：从结构设计到集成系统以实现智能纳米级生物传感器
Precious Asumadu,Zhuowen Guo,Shuo Qi et al.
Precious Asumadu et al.
DNA aptamer-based logic gates represent significant advances in molecular computing, enabling complex biological computations at the nanoscale. These systems leverage the unique programmable properties of DNA aptamers-short, single-stranded...
Quantification of poly(ethylene terephthalate) in environmental samples after methanolysis via gas chromatography-mass spectrometry [0.03%]
甲醇解后再通过气相色谱-质谱法量化环境样品中的聚对苯二甲酸乙二醇酯
Tim Lauschke,Ann-Christin Merfels,Thomas A Ternes et al.
Tim Lauschke et al.
Quantification of the polyester poly(ethylene terephthalate) (PET) in environmental samples is a particular challenge. Due to strong matrix effects by inorganic compounds, thermoanalytical methods are not recommendable for a precise quantif...
Liquid chromatography-mass spectrometry approach for characterizing sucrose isomers in complex mono-floral honey [0.03%]
一种用于表征复杂单花蜂蜜中蔗糖异构体的液相色谱-质谱方法
Enoch Amoah,Santosh Raman Acharya,Ayesha Seth et al.
Enoch Amoah et al.
Sucrose, which forms < 2% of the chemical content in honey samples, is known to have five structural isomers each with its own medicinal benefits. Unfortunately, studies characterizing the specific sucrose isomer(s) present in honey samples...
On the question of correct use of replicates in quantitative label-free proteomics [0.03%]
关于定量非标记蛋白质组学中正确使用重复的思考
Leyla A Garibova,Mikhail V Gorshkov,Mark V Ivanov
Leyla A Garibova
Label-free quantitation is the most popular method in proteomics for assessing changes in protein concentrations. However, practical aspects like the optimal use of technical replicates, the impact of removing low-identified protein runs, a...
Automated thermal desorption-gas chromatography/mass spectrometry for screening of hazardous chemicals in cotton and cotton blend garments-analytical challenges [0.03%]
棉和混纺服装中危险化学品筛查的自动化热脱附-气相色谱/质谱法及分析挑战
Tim Åström,Conny Östman,Ioannis Sadiktsis et al.
Tim Åström et al.
The global production of textiles involves large amounts of health-hazardous chemicals, constituting possible health risks since residues usually remain in the finished garments. In the present study, a recently published ATD-GC/MS methodol...
Protein pellet sample preparation for the analysis of N-glycans of therapeutic proteins [0.03%]
药物蛋白样品制备用于分析糖链结构
Ronald L Kowle,Shardrack O Asare
Ronald L Kowle
Profiling of N-glycans of therapeutic proteins is a critical component in the control of biopharmaceutical products. N-Glycosylation, a common post-translational modification has been shown to impact the structure, function, stability, phar...
Louis V Hellequin,Vicent J Borràs,Patrick Romann et al.
Louis V Hellequin et al.
Raman spectroscopy has become increasingly popular in the process analytical technology (PAT) landscape due to its versatility and predictive capability in bioprocesses. However, model building remains a time-consuming and cost-intensive ta...
Stick-and-test: simple tape-based devices for SARS-CoV-2 isothermal molecular detection [0.03%]
一步合成的新型冠状病毒(SARS-CoV-2)恒温分子检测试纸条
Paulo Felipe Neves Estrela,Marcio Neres de Souza Júnior,Kézia Gomes de Oliveira et al.
Paulo Felipe Neves Estrela et al.
Portable analytical devices have been enabling point-of-care molecular diagnostic applications. However, the laborious preparation of conventional microdevices still limits their broader use, especially in resource-limited settings in micro...
Development of calcium alginate gel sphere-based SERS substrates for minimally invasive sampling and identification of indigo on the surface of simulated murals and aged imitation cultural relic samples [0.03%]
基于钙铝酸盐凝胶球的SERS基底的构建及在壁画和文物仿制品表界面藏蓝花的非破坏性鉴别中的应用研究
Xuerong Shi,Wanru Wang,Xinyu Xie et al.
Xuerong Shi et al.
Pigments in painted cultural relics serve as critical historical evidence, offering significant research value for understanding historical contexts and cultural development processes. However, the pigments, especially organic pigments (or ...
A mass spectrometry-based assay for mouse IgG N-glycan screening in biofluids [0.03%]
基于质谱的鼠IgG糖型分析方法及其在生物体液中的应用筛查
Ariana E Stratton,Hassan Moussa,Yingchan Guo et al.
Ariana E Stratton et al.
N-Glycans represent an important post-translational modification of proteins that can serve as biomarkers of disease, injury, and inflammation. N-Glycosylation of the monoclonal antibody immunoglobulin G (IgG) impacts binding to receptors t...