Structural and functional optimization of COF-coated stirring bars for environmental monitoring and biological sample analysis [0.03%]
用于环境监测和生物样品分析的涂有COF的搅拌棒的结构与功能优化
Lianzhi Wang,Xixi Lian,Jianing Sun et al.
Lianzhi Wang et al.
In this study, a series of covalent organic framework (COF)-coated stirring bars-COF-a, COF-b, and COF-c-were innovatively designed and evaluated for the efficient extraction of estrogens from complex environmental and biological samples. T...
Efficient and sustainable recovery of bioactive compounds from cashew nut testa shell (Anacardium occidentale L.) using pressurized liquid extraction [0.03%]
高效且可持续地从现金果皮壳（Anacardium occidentale L.）中利用加压液体萃取法回收生物活性化合物
Jonas da Silva,Anderson Felipe Viana da Silva,Karina Cesca et al.
Jonas da Silva et al.
Cashew nut processing generates large quantities of byproducts daily, such as cashew nut testa shell (CNTS), which is discarded, leading to environmental and economic issues. However, CNTS contains bioactive substances such as polyphenols a...
Functionalized magnetic covalent organic frameworks with refining tunable cores for highly selective adsorption of immunosuppressive drugs [0.03%]
用于免疫抑制药物高选择性吸附的官能化磁性共价有机框架 Campos 中央实验室研究人员开发了一种新型磁性共价有机框架（MCOFs），该材料可实现对血液中免疫抑制剂的有效清除。
Jianhua Shi,Jin Huang,Jiang Qing et al.
Jianhua Shi et al.
Immunosuppressant drugs (ISDs) are widely used in the treatment of organ rejection following human transplantation and in autoimmune diseases. Herein, this study demonstrates that carbonylated covalent organic frameworks (COFs) with pore-ma...
Anil Kumar Meher,Abdennour Abbas
Anil Kumar Meher
Traditional methods for diagnosing bacterial or fungal infections, such as cell culture, are comprehensive but time-consuming and subjective. Microbial volatile organic compound (VOC) analysis offers a faster alternative, though challenges ...
Unraveling the molecular dynamics of wound healing: integrating spatially resolved lipidomics and temporally resolved proteomics [0.03%]
揭秘伤口愈合的分子动态过程：整合空间分辨脂质组学和时间分辨蛋白质组学
Hongxia Bai,Alejandra Suarez Arnedo,Yining Liu et al.
Hongxia Bai et al.
Understanding the spatial-temporal molecular dynamics of wound healing is crucial for devising effective treatments. Three-dimensional mass spectrometry imaging (3D MSI) enables the comprehensive visualization of molecular distribution thro...
Mass spectrometry analysis of PM2.5 in poultry farms and the cytotoxicity and metabolism perturbation of BEAS-2B cells [0.03%]
鸡舍PM2.5的质谱分析及其对支气管上皮细胞系BEAS-2B毒性和代谢影响的研究
Xia Liu,Lei Yan,Jia Wang et al.
Xia Liu et al.
To evaluate the potential risks posed by farm-derived fine particulate matter (PM2.5), we conducted a comprehensive analysis of PM2.5 samples collected from chicken farms. Specifically, water-soluble ions, metal and metalloids, and volatile...
Testing of a novel automated point-of-care analyzer for blood ammonium monitoring in a clinical setting [0.03%]
临床环境下一种新型自动化POCT氨离子检测仪的测试研究
Beatriz Rebollo-Calderón,Antonio Calvo-López,Aida Ormazábal et al.
Beatriz Rebollo-Calderón et al.
Certain diseases are marked by elevated ammonium levels in the blood, a condition known as hyperammonemia. Prompt detection and medical intervention are crucial to prevent potentially fatal outcomes. Therefore, ammonium levels should be mon...
Quality assurance and quality control for human biomonitoring data-focus on matrix reference materials [0.03%]
人类生物监测数据的质量保证和质量控制-重点是基质参考材料
Đorđe Tadić,Ana Pires de Lima,Marina Ricci
Đorđe Tadić
Human biomonitoring (HBM) is an essential tool for making evidence-based policy decisions upon assessment of human exposure to pollutants. In contrast, the heterogeneity of data reliability across studies has been identified as a weakness i...
Combination of hydrophilic interaction liquid chromatography and top-down mass spectrometry for characterisation of adeno-associated virus capsid proteins [0.03%]
结合亲水性相互作用液相色谱与顶空质谱分析腺相关病毒衣壳蛋白
Corentin Beaumal,Felipe Guapo,Josh Smith et al.
Corentin Beaumal et al.
Adeno-associated virus (AAV) viral vector-based gene therapy is advancing rapidly, offering potential treatments for rare and severe diseases. The AAV capsid consists of a combination of three viral proteins (VPs), VP1, VP2, and VP3, rangin...
Quality evaluation of metabolite annotation based on comprehensive simulation of MS/MS data from high-resolution mass spectrometry (HRMS) and similarity scoring [0.03%]
基于高分辨率质谱（HRMS）和相似性评分的MS/MS数据全面仿真代谢物注释的质量评价
Yingjiao Shi,Ji Yang,Qianxu Yang et al.
Yingjiao Shi et al.
Metabolite annotation is a critical step in discovery metabolomics, but remains a significant challenge. In this study, the accuracy of metabolite annotation was systematically evaluated by leveraging the proposed strategies for simulation ...