Rossella Svigelj,Noemi Dassi,Andrea Gorassini et al.
Rossella Svigelj et al.
In this study, an electrochemical smartphone-based aptasensor for the determination of fipronil was developed by modifying a screen-printed carbon electrode (SPCE). Fipronil is a broad-spectrum insecticide that has been widely used in vario...
Comprehensive profiling and semi-quantification of exogenous chemicals in human urine using HRMS-based strategies [0.03%]
基于HRMS策略的人尿外源性化学物质的全面剖析与半定量研究
Daniel Gutiérrez-Martín,Esteban Restrepo-Montes,Oksana Golovko et al.
Daniel Gutiérrez-Martín et al.
Chemicals infiltrate our daily experiences through multiple exposure pathways. Human biomonitoring (HBM) is routinely used to comprehensively understand these chemical interactions. Historically, HBM depended on targeted screening methods l...
Nanoleaf-derived carbon materials as a sensitivity coating for solid‑phase microextraction of polycyclic aromatic hydrocarbons [0.03%]
基于纳米叶的碳材料作为多环芳烃固相微萃取敏感涂层
Xingru Hu,Long Pang,Mingkai Wu et al.
Xingru Hu et al.
Metal-organic framework-derived carbon materials have shown extensive application in the sensitive extraction of polycyclic aromatic hydrocarbons (PAHs), but more active sites for its adsorption were still a tireless pursuit. In this study,...
Differentiation of steroid isomers by steroid analogues adducted trapped ion mobility spectrometry-mass spectrometry [0.03%]
类固醇类似物加合物的封闭型离子淌度质谱分析及类固醇异构体的鉴别
Yang Li,Yujiao Qin,Songchang Wei et al.
Yang Li et al.
Steroids are one of the important indicators of health and disease. However, due to the high similarity of steroid structures, there are several potential obstacles in the differentiation of steroids, especially for their isomers. Herein, w...
Targeted LC-MS/MS profiling of bile acids reveals primary/secondary bile acid ratio as a novel biomarker for necrotizing enterocolitis [0.03%]
靶向LC-MS/MS胆汁酸分析发现主要/次要胆汁酸比例可作为坏死性小肠结肠炎的新生物标志物
Tingting Gao,Shaohua Hu,Weijue Xu et al.
Tingting Gao et al.
Bile acids (BAs) are involved in the development of necrotizing enterocolitis (NEC), which mainly occurs in preterm infants. We aim to identify the change of BAs in preterm infants and validate its potential value in the detection of NEC. T...
Enhancing uric acid electrochemical detection with copper ion-activated mini protein mimicking uricase within ZIF-8: response surface methodology (RSM) optimization [0.03%]
铜离子激活的ZIF-8内迷你蛋白仿生尿酸酶增强电化学检测：响应面法（RSM）优化
Siti Fatimah Nur Abdul Aziz,Ong Sin Hui,Abu Bakar Salleh et al.
Siti Fatimah Nur Abdul Aziz et al.
This study aims to investigate the influence of copper(II) ions as a cofactor on the electrochemical performance of a biocomposite consisting of a mini protein mimicking uricase (mp20) and zeolitic immidazolate framework-8 (ZIF-8) for the d...
LAMP assay coupled with a CRISPR/Cas12a system for the rapid and ultrasensitive detection of porcine circovirus-like virus in the field [0.03%]
用于检测现场猪圆环病毒样病毒的LAMP与CRISPR/Cas12a系统联合测定法
Zhaorong Yu,Hua Liu,Zhe Chen et al.
Zhaorong Yu et al.
A recent outbreak of porcine circovirus-like virus (PCLV), a virus that may be associated with porcine diarrhea, has been reported in swine herds in China. The virus is spreading rapidly, causing huge economic losses to the swine farming in...
Biosynthesis of magnetosome-nanobody complex in Magnetospirillum gryphiswaldense MSR-1 and a magnetosome-nanobody-based enzyme-linked immunosorbent assay for the detection of tetrabromobisphenol A in water [0.03%]
利用磁小体-纳米抗体复合体系在MSR-1菌株中生物合成磁小体及免疫检测四溴双酚A
Sha Wu,Jiesheng Tian,Xianle Xue et al.
Sha Wu et al.
In this study, two mutant strains, TBC and TBC+, able to biosynthesize a novel functional magnetosome-nanobody (Nb), were derived from the magnetotactic bacteria Magnetospirillum gryphiswaldense MSR-1. The magnetosome-Nbs biosynthesized by ...
A SYBR Green I-based aptasensor for the label-free, fluorometric, and anti-interference detection of MeHg [0.03%]
一种基于SYBR Green I的汞甲基化特异性适配体用于无标记、防干扰的甲基汞检测方法
Xiaoyan Wang,Yinuo Qiao,Jinyang Zhang et al.
Xiaoyan Wang et al.
Methylmercury (MeHg+) is a common form of organic mercury that is substantially more toxic than inorganic mercury and is more likely to accumulate in organisms through biological enrichment. Therefore, developing a method to enable the spec...
Transistor-based immunosensor using AuNPs-Ab2-HRP enzyme nanoprobe for the detection of antigen biomarker in human blood [0.03%]
基于AuNPs-Ab2-HRP酶纳米探针的场效应免疫传感器检测人体血液中的抗原标志物
Rong Zou,Lei Cao,Nan Wu et al.
Rong Zou et al.
Alpha-fetoprotein (AFP) is inextricably linked to various diseases, including liver cancer. Thus, detecting the content of AFP in biology has great significance in diagnosis, treatment, and intervention. Motivated by the urgent need for aff...