Dissecting the neuronal mechanisms of pinoresinol against methamphetamine addiction based on network and experimental pharmacology [0.03%]
基于网络和实验药理学的愈创树脂酚对抗甲基苯丙胺成瘾的神经机制研究
Shuyuan Fan,Yize Qi,Fukang Zhang et al.
Shuyuan Fan et al.
Background: Addiction is a chronic brain disease in which the underlying neuronal mechanism is characterized by drug-seeking and use. Flos Daturae (FD) and its components are used to treat addiction. However, the effectiv...
Inhibition of PKM2 by shikonin impedes TGF-β1 expression by repressing histone lactylation to alleviate renal fibrosis [0.03%]
虾青素通过抑制组蛋白乳酸化来阻滞PKM2表达从而缓解肾纤维化的机制研究
Tianya Xiang,Xijian Wang,Shujiao Huang et al.
Tianya Xiang et al.
Background: Macrophage-myofibroblast transition (MMT) plays a significant role in the progression of renal fibrosis in chronic kidney disease (CKD), making inhibition of MMT a promising therapeutic strategy. Pyruvate kina...
Xinkeshu formula restrains pathological cardiac hypertrophy through metabolic remodeling via AMPK/mTOR pathway [0.03%]
新keesu配方通过AMPK/mTOR途径的代谢重塑来抑制病理性心脏肥厚
Yi-Jing Zhao,Wen-Hui Wu,Kai-Ming Niu et al.
Yi-Jing Zhao et al.
Background: Xinkeshu (XKS) formula is a patented traditional Chinese medicine used to treat cardiovascular diseases for decades. However, little is known about its potential influence on heart metabolism under pathologica...
Polyphenol extract from Tagetes erecta L. flowers stimulates osteogenesis via β-catenin activation [0.03%]
Tagetes erecta L.花朵提取物通过激活β-连环素促进骨发生
Sobarathne Senel Sanjaya,Jinkuk Park,Yung Hyun Choi et al.
Sobarathne Senel Sanjaya et al.
Background: Osteoporosis, a prevalent bone disorder, results in reduced bone mineral density and mass. With minimal side effects, medicinal plant-based natural remedies are increasingly explored for osteoporosis. However,...
Health and economic evaluation of herbal medicines for heart failure: A population-based cohort study [0.03%]
基于人群的队列研究中草药治疗心脏衰竭的健康和经济效益评估
Jianbo Guo,Xinyu Lu,Pei Zhang et al.
Jianbo Guo et al.
Background: Heart failure (HF) represents an advanced stage of various cardiovascular disorders, with its elevated admission rates and resultant health economic burden posing an ongoing global concern. ...
Targeting PPARα/γ by icariside II to rescue GalN/LPS-induced acute liver injury in mice: Involvement of SIRT6/NF-κB signaling pathway [0.03%]
通过激活PPARα/γ信号通路缓解急性肝损伤的淫羊藿苷II及其机制研究
Miao-Xian Gong,Jia-Jia Wei,Yang Yi et al.
Miao-Xian Gong et al.
Background: Peroxisome proliferator-activated receptor α and-γ (PPARα/γ) are known to play crucial roles in acute liver injury (ALI). Icariside II (ICS II), a natural flavonoid compound derived from Herba EpimedII, co...
Polygonatum sibiricum polysaccharide ameliorates skeletal muscle aging and mitochondrial dysfunction via PI3K/Akt/mTOR signaling pathway [0.03%]
Polygonatum sibiricum多糖通过PI3K/Akt/mTOR信号通路改善骨骼肌衰老和线粒体功能障碍
Yang Li,Zhongyuan Liu,Hongyu Yan et al.
Yang Li et al.
Background: Sarcopenia is currently a life-threatening disease for the elderly. Polygonatum sibiricum polysaccharide (PSP) has anti-oxidative stress and anti-inflammatory effects. However, the effects of PSP on skeletal m...
Corrigendum to "Bushen Huoxue Yiqi formula alleviates cardiac fibrosis in ischemic heart failure through SIRT1/Notch1 pathway-mediated EndMT" [Phytomedicine Journal 135 (2024) 156252] [0.03%]
补肾活血益气方通过SIRT1/Notch1途径介导的内皮-间充质转化减轻缺血性心力衰竭心脏纤维化的校正案 [Phytomedicine Journal 135 (2024) 156252]
Cong Chen,Jie Wang,Chengzhi Hou et al.
Cong Chen et al.
Corrigendum "Enhancement of gemcitabine efficacy by K73-03 via epigenetically regulation of miR-421/SPINK1 in gemcitabine resistant pancreatic cancer cells" [Phytomedicine 2021:91:153711] [0.03%]
“K73-03通过表观遗传调控miR-421/SPINK1增强吉西他滨对胰腺癌吉西他滨耐药性细胞的疗效”校正案 [Phytomedicine 2021:91:153711]
Abdullah Shopit,Xiaodong Li,Shisheng Wang et al.
Abdullah Shopit et al.
Corrigendum to "Ilexchinene, a new seco-ursane triterpenoid from the leaves of Ilex chinensis with therapeutic effect on neuroinflammation by attenuating the MAPK/NF-κB signaling pathway" [Phytomedicine 121 (2023) 155110] [0.03%]
番木瓜茋，一种从糙叶树中分离出的新的倍半木质素生物碱，通过抑制MAPK / NF-κB信号通路对神经炎症有治疗作用（论文发表在Phytomedicine期刊第121卷（2023年）155110页上的更正说明
Siyuan Shao,Ruofei Li,Kexin Wang et al.
Siyuan Shao et al.