Gingerols: Preparation, encapsulation, and bioactivities focusing gut microbiome modulation and attenuation of disease symptoms [0.03%]
姜辣素：制备、包封及生物活性聚焦于调节肠道菌群和缓解疾病症状
Abdullah,Naveed Ahmad,Jie Xiao et al.
Abdullah et al.
Background: Gut dysbiosis, chronic diseases, and microbial recurrent infections concerns have driven the researchers to explore phytochemicals from medicinal and food homologous plants to modulate gut microbiota, mitigate...
Salvianic acid A ameliorates atherosclerosis through metabolic-dependent anti-EndMT pathway and repression of TGF-β/ALK5 signaling [0.03%]
salvianic酸A通过代谢依赖性抗内皮-间充质转化途径和抑制TGF-β / ALK5信号通路改善动脉粥样硬化
Yijun Gao,Fei Ye,Yafen Dong et al.
Yijun Gao et al.
Background: Endothelial-to-mesenchymal transition (EndMT) has been identified as a key factor to the initiation and progression of the pathogenesis of atherosclerosis (AS). Salvianic acid A (SAAS) is the primary water-sol...
Mechanistic insights into the anti-oxidative and anti-inflammatory functions of covalent-reactive cinnamyl compounds within Cinnamomum cassia [0.03%]
肉桂化合物的抗氧化和抗炎功能的机理研究——丙烯酰反应型单体肉桂类化合物抑制氧化应激及炎症机制研究
Lu Jin,Huayong Peng,Yingchao Wang et al.
Lu Jin et al.
Background: Cinnamomum cassia Presl (Lauraceae) is widely used as a medicinal plant in the folk medicine and pharmaceutic industry, for its promising anti-inflammatory, anti-oxidative, and anti-bacterial function. However...
Xiaohuafuning tang intervenes liver-depression-and-spleen-deficiency syndrome chronic-atrophic-gastritis by reshaping amino acid metabolism through gut Microbiota [0.03%]
小花龙藤汤通过重塑氨基酸代谢干预肝郁脾虚证慢性萎缩性胃炎的研究
Li Chen,ShaoYu Xu,Sheng Wang et al.
Li Chen et al.
Background: Xiaohua Funing Tang (XHFND) is a decoction formula of traditional Chinese medicine (TCM) and possesses the potential to manage chronic atrophic gastritis (CAG) with liver depression and spleen deficiency (LDSD...
Schisandra sphenanthera extract modulates sweet taste receptor pathway, IRS/PI3K, AMPK/mTOR pathway and endogenous metabolites against T2DM [0.03%]
五味子丙素通过调节甜味受体信号通路、IRS/PI3K、AMPK/mTOR信号通路及内源性代谢物治疗2型糖尿病的作用机制研究
Shibo Feng,Jiaojiao Wang,Qin Peng et al.
Shibo Feng et al.
Background: Southern Schisandra is the dried and matured fruit of Schisandra sphenanthera Rehd. et Wils. in the family of Magnoliaceae; Traditional medicine reports that Schisandra sphenanthera has astringent and astringe...
Rebalancing immune homeostasis in combating disease: The impact of medicine food homology plants and gut microbiome [0.03%]
对抗疾病中免疫平衡的作用：药食同源植物和肠道微生物的影响
Lu Xia,Chuangen Li,Jia Zhao et al.
Lu Xia et al.
Background: Gut microbiota plays an important role in multiple human physiological processes and an imbalance in it, including the species, abundance, and metabolites can lead to diseases. These enteric microorganisms mod...
Bioinformatics identification based on causal association inference using multi-omics reveals the underlying mechanism of Gui-Zhi-Shao-Yao-Zhi-Mu decoction in modulating rheumatoid arthritis [0.03%]
基于因果推断的多组学分析揭示桂枝芍药知母汤治疗类风湿关节炎的作用机制
Jiayue Yang,Heng Yang,Fumin Wang et al.
Jiayue Yang et al.
Object: Rheumatoid arthritis (RA) is a prevalent and currently incurable autoimmune disease. Existing conventional medical treatments are limited in their efficacy, prolonged disease may lead to bone destruction, joint de...
Sappanone A alleviates metabolic dysfunction-associated steatohepatitis by decreasing hepatocyte lipotoxicity via targeting Mup3 in mice [0.03%]
姜黄素衍生物苏木酚酮A通过靶向MUP3降低肝细胞脂毒性从而缓解代谢紊乱相关性steatohepatitis
An Zhu,Xueqing Yan,Mengting Chen et al.
An Zhu et al.
Background and purpose: Metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory lipotoxic disorder marked by hepatic steatosis, hepatocyte damage, inflammation, and varying stages of fibrosis. Sappanone...
Artesunate disrupts ribosome RNA biogenesis and inhibits ovarian cancer growth by targeting FANCA [0.03%]
Arteminate通过靶向FANCA干扰核糖体RNA的生成并抑制卵巢癌生长
Yuyan Wei,Fengying Liu,Xialin Zhu et al.
Yuyan Wei et al.
Background: The dysregulation of ribosome biogenesis has been extensively identified in various cancers, making it emerge as a hallmark of malignant cells. This highlights the potential of targeting ribosome biogenesis as...
Comparative chloroplast genome analyses provide new insights into molecular markers for distinguishing Arnebiae Radix and its substitutes (tribe Lithospermeae, Boraginaceae) [0.03%]
比较型质体基因组分析为区分阿魏根及其代用品提供新的分子标记见解（博朗科族 Lithospermeae）
Sheng Wang,Yiheng Wang,Jiahui Sun et al.
Sheng Wang et al.
Background: Arnebiae Radix has long been used in traditional medicine for its pleiotropic properties. However, distinguishing Arnebiae Radix from its substitutes or closely related species has been challenging due to limi...