Cortex Dictamni-induced hepatotoxicity by enhanced oxidative phosphorylation: Insights from integrative transcriptomics, proteomics, and metabolomics analyses [0.03%]
毛壳烷诱导的肝脏毒性通过增强氧化磷酸化产生：整合转录组学、蛋白质组学和代谢组学分析的结果
Huijuan Sun,Yu Wang,Geyu Deng et al.
Huijuan Sun et al.
Background: Cortex Dictamni (CD) is a traditional Chinese medicine that is commonly used to treat various skin diseases. Recently, clinical reports have highlighted its potential to induce severe hepatotoxicity. However, ...
Centipeda minima extract exhibits anti-liver cancer effects via the ER stress/HMOX1/Fe2+/ROS pathway [0.03%]
黄毛鼠尾草提取物通过ER应激/HMOX1/ Fe2+/ ROS通路发挥抗肝癌作用
Jinrui Wei,Xuqi Zhao,Baixuan Wu et al.
Jinrui Wei et al.
Background: Centipeda minima (CM), also known as Ebushicao, has been traditionally utilized in Chinese medicine over thousands of years to address rhinitis, nasal allergies, and cancers. However, the active compounds and ...
Curcuma wenyujin extract alleviates cognitive deficits and restrains pyroptosis through PINK1/Parkin mediated autophagy in Alzheimer's disease [0.03%]
姜黄属wenyujin提取物通过PINK1/Parkin介导的自噬减轻阿尔茨海默病的认知缺陷并抑制细胞焦亡
Yu Qi,Jingwen Zhang,Yuanlong Zhang et al.
Yu Qi et al.
Background: Pyroptosis and mitophagy have gained significant attention in Alzheimer's disease (AD) treatment. Curcumae Radix (CR), the dried radix of Curcuma wenyujin Y. H. Chen et C. Ling, is a traditional Chinese medici...
Maintained homeostasis: LGYD facilitated the restoration of ISCs following radiation exposure by activating Hes1 [0.03%]
维持稳态：LGYD通过激活Hes1促进辐射暴露后ISCs的恢复
Ziqiao Yan,Yangshuo Li,Mingyang Chang et al.
Ziqiao Yan et al.
Background: Radiation-induced Intestinal Injury (RIII) affects quality of life in radiotherapy patients; Liangxue Guyuan Yishen Decoction (LGYD) offers protection but requires further study on its mechanism. ...
Histones are critical toxic factors in gut lymph of severe acute pancreatitis: Neutralization by baicalin and baicalein for protection [0.03%]
组蛋白是在严重急性胰腺炎的肠淋巴中有毒的关键因素：牛磺熊去氧胆酸和黄芩苷、黄芩素中和后的保护作用
Shiyu Liu,Qiqi Wang,Wenjuan Luo et al.
Shiyu Liu et al.
Background: Whether circulating histones in gut lymph contribute to organ failure and impact of chaiqin chengqi decoction (CQCQD) on histones in severe acute pancreatitis (SAP) remain elusive. ...
Exploring the anti-inflammatory effects of Radix Curcumae essential oil in pulmonary sarcoidosis via the TLR4/MyD88/NF-κB pathway [0.03%]
姜黄根精油通过TLR4/MyD88/NF-κB通路在肺结节病中的抗炎作用研究
Zhiguo Mao,Xiangke Lin,Yilong Hu et al.
Zhiguo Mao et al.
Background: Pulmonary sarcoidosis (PS) is an immune-mediated disorder characterised by a significant association with various immune cell types including macrophages, T-helper 1 (TH1) cells, and TH17 cells. Dysregulation ...
Exploring trends in natural product-based treatments to skin burn: A comprehensive review [0.03%]
基于天然产物的烧伤治疗趋势探索：全面回顾
José Adão Carvalho Nascimento Júnior,Ana Maria Santos Oliveira,Karen Dayana Lancheros Porras et al.
José Adão Carvalho Nascimento Júnior et al.
Background: Burns are traumatic injuries caused by thermal, chemical, or other external factor, significantly impacting organic tissue. They are among the most common and severe types of trauma worldwide, often resulting ...
The effect of Yinhuang Hanhua dropping pill on acute pharyngitis via a systematic "Compound-Target-Pathway" analysis [0.03%]
茵黄汉花滴丸通过系统“化合物-靶点-通路”分析对急性咽炎的影响
Qing Zhao,Xiaohuan Wang,Yang Jin et al.
Qing Zhao et al.
Background: Yinhuang Hanhua dropping pill (YHHHDP) is a Chinese herbal formula that is commonly used in medical practice for managing of acute pharyngitis (AP) and other upper respiratory tract infections. However, the ac...
Astaxanthin alleviates spinal nerve ligation-induced neuropathic pain by modulating propionic acid levels [0.03%]
角黄素通过调节丙酸水平缓解由脊神经结扎引起的感觉神经疼痛
Jingwu Li,Daosong Dong,Yanbin Sun et al.
Jingwu Li et al.
Background: The treatment for neuropathic pain (NP) remains challenging. Propionic acid (PA), derived from gut microbiota, is a promising therapeutic target for NP. However, the precise role of PA in NP is nebulous; furth...
Unraveling the role of Globularia species in modern medicine based on evidence from photochemistry, traditional uses and biological activities [0.03%]
基于光化学、传统用途和生物活性的证据，揭示Globularia物种在现代医学中的作用
Hesham R El-Seedi,Aya Sabry,Tariq Z Abolibda et al.
Hesham R El-Seedi et al.
Background: Species of the genus Globularia exist in the Mediterranean region spreading upon Macaronesia, northern Europe, and north-eastern Africa. They have valuable biological activities and remarkable phytochemical co...