Anti-inflammatory effects of Rhus javanica ethanol extract for pulmonary and colonic disorders [0.03%]
藤黄乙醇提取物的抗炎作用对肺部和结肠疾病的治疗效果研究
Lei Huang,Jinghan Su,Yuhao Wang et al.
Lei Huang et al.
Background: Rhus javanica is a traditional medicinal herb widespread in East Asia, including Korea, China, and Japan. Valued for its antidiarrheal, bactericidal, and anti-inflammatory properties, it epitomizes the synergy...
The effects and mechanisms of aqueous Persicaria capitata extract on uropathogenic Escherichia coli adhesion [0.03%]
尾孢草提取物对大肠杆菌尿路感染的效应及机制研究
Yang Zhou,Zuying Zhou,Lin Jin et al.
Yang Zhou et al.
Background: Urinary tract infections (UTIs) in humans are common, with uropathogenic Escherichia coli (UPEC) being the primary pathogen. The adhesive capabilities of UPEC are a substantial pathogenicity factor. Due to lim...
Guizhi Fuling capsules can alleviate bortezomib-induced peripheral neuropathy by decreasing Interleukin-6 levels to regulate mTOR pathway-induced autophagy [0.03%]
桂枝茯苓胶囊通过降低白介素6水平调节mTor通路诱导的自噬来缓解万珂引起的周围神经病变
Jiaqi Fu,Qian Li,Runjie Sun et al.
Jiaqi Fu et al.
Objective: To investigate the therapeutic effect and underlying mechanism of Guizhi Fuling capsule (GZFL) on bortezomib-induced peripheral neuropathy (BiPN). ...
Therapeutic potential of p-coumaric acid in alleviating renal fibrosis through inhibition of M2 macrophage infiltration and cellular communication [0.03%]
通过抑制M2巨噬细胞浸润和细胞通讯减轻肾纤维化的治疗潜力的研究
Qinfan Yao,Xinyi Zhang,Lefeng Wang et al.
Qinfan Yao et al.
Background: p-coumaric acid (p-CA), a hydroxycinnamic acid derivative, is recognized for its antioxidant and anti-inflammatory properties; however, its pharmacological effects on renal fibrosis remain insufficiently explo...
6'-O-caffeoylarbutin of Vaccinium dunalianum alleviated ischemic stroke through the PI3K/AKT/NF-κB pathway [0.03%]
羊茅蓝莓中6'-O-咖啡酰阿鲁宾通过PI3K/AKT/NF-κB通路缓解缺血性脑卒中
Zhuo-Qi Shi,Xi Wen,Xian-Run Wu et al.
Zhuo-Qi Shi et al.
Background: Vaccinium dunalianum ("Que Zui Tea") has been traditionally consumed as a tea substitute in Yunnan, China, for its health benefits, i.e., improving vascular health. 6'-O-caffeoylarbutin (CA) is its major bioac...
JTCD attenuates HF by inhibiting activation of HSCs through PPARα-TFEB axis-mediated lipophagy [0.03%]
JTCD通过PPARα-TFEB轴介导的脂自噬抑制HSC激活从而减轻心力衰竭
Chang Shao,Wenfang Lan,Ying Ding et al.
Chang Shao et al.
Background: Hepatic fibrosis (HF) is an intermediate stage in the progression of chronic liver disease to cirrhosis and has been shown to be a reversible pathological process. Known evidence suggests that activation of he...
Yinzhihuang formula modulates the microbe‒gut‒liver axis and bile acid excretion to attenuate cholestatic liver injury [0.03%]
茵栀黄方通过调节菌群-肠道-肝脏轴和胆汁酸排泄减轻胆汁淤积性肝损伤
Xin Luo,Peng Cheng,Yuan Fang et al.
Xin Luo et al.
Background: Cholestatic liver injury is a hepatobiliary disorder primarily characterized by cholestasis, which significantly contributes to liver damage. The Yinzhihuang (YZH) oral preparation is an effective clinical tre...
Effect of Qishen Yiqi dripping pills on the classification of ejection fraction in patients with ischaemic heart failure: A prospective cohort study [0.03%]
芪参益气滴丸对缺血性心力衰竭患者射血分数分级的影响：一项前瞻性队列研究
Zhou Zhou,Shuai Wang,Zixuan Fan et al.
Zhou Zhou et al.
Background: In patients with heart failure (HF), improved left ventricular ejection fraction (LVEF) classification is closely associated with increased survival rates. However, even patients receiving guideline-directed m...
Beta-hydroxy-beta-methylbutyrate (HMB) ameliorates DSS-induced colitis by inhibiting ERK/NF-κB activation in macrophages [0.03%]
β-羟基-β-甲基丁酸(HMB)通过抑制巨噬细胞中的ERK/NF-κB活化改善DSS诱导的结肠炎
Jiao Liu,Danye Niu,Yu Tang et al.
Jiao Liu et al.
Background: β-Hydroxy β-Methylbutyrate (HMB), derived from leucine, is known for its role in anti-oxidation and anti-inflammation. But, the application of HMB in IBD treatment is not fully understood, highlighting the r...
Yanghe Pingchuan granules induce ferroptosis in airway smooth muscle cells to improve bronchial asthma via the METTL3/P53/SLC7A11 signaling pathway [0.03%]
杨河平原颗粒通过METTL3/P53/SLC7A11信号通路诱导气道平滑肌细胞发生铁死亡从而改善支气管哮喘的研究
Lingyu Pan,Bangfu He,Yanquan Han et al.
Lingyu Pan et al.
Background: Recent studies have found that ferroptosis is strongly associated with the development of bronchial asthma (BA). However, the mechanism underlying the role of ferroptosis in asthma remains unclear. Yanghe Ping...