Lycium barbarum polysaccharides alleviate experimental autoimmune prostatitis by putrescine/TRAF/JAK/STAT-mediated Th17 differentiation [0.03%]
枸杞多糖通过尸胺/TRAF/JAK/STAT介导的Th17分化治疗实验性自身免疫前列腺炎
Xu Wang,Shao-Yu Yue,Lei Chen et al.
Xu Wang et al.
Background: Due to its often refractory nature, chronic prostatitis (CP) is a prevalent disorder that notably impacts the quality of life of 20-40-year-old men worldwide. Lycium barbarum polysaccharides (LBPs) have a broa...
Gut microbiome and glial cell dialog: Role of TCM in the treatment of depression [0.03%]
肠道微生物与胶质细胞对话:中医治疗抑郁症的作用
Xue Zhang,Xiaodan Chen,Songxue Ruan et al.
Xue Zhang et al.
Background: Depression is characterized by low mood, cognitive slowing and a tendency to self-harm, and has a complex etiology involving abnormalities in neuromodulation (e.g., monoamine transmitter imbalance and reduced ...
Efficacy and safety of Shen-Qi Paste, a Traditional Chinese Medicine, in dialysis patients with sarcopenia: A randomized, double-blind, placebo-controlled trial [0.03%]
补肾贴膏治疗维持性血液透析患者肌少症的疗效及安全性:随机、双盲、安慰剂对照试验
Xiaoyan Li,Rongyun Wang,Keda Lu et al.
Xiaoyan Li et al.
Background: The lack of effective treatments for sarcopenia remains a major unmet medical need. Shen-Qi Paste (SQP), a Traditional Chinese Medicine (TCM) dietary formulation developed on the basis of the theory of "same o...
Yangyin Shugan capsule ameliorates premature ovarian insufficiency via dual receptor-mediated cascade in rats [0.03%]
养阴舒肝胶囊通过双向受体介导的级联反应改善卵巢早衰的作用研究
Jiarui Hou,Xuchun Huang,Xiaojing Cao et al.
Jiarui Hou et al.
Background: Premature ovarian insufficiency (POI) is a significant health issue for women under 40, characterized by declining ovarian function, hormonal imbalance, and various long-term health consequences. Current hormo...
Traditional wisdom meets modern science: The protective role of sanhuang shu'ai decoction in ulcerative colitis models [0.03%]
传统智慧与现代科学的结合:三黄泻心汤防治溃疡性结肠炎的作用研究
Nianchao Zhang,Amei Liu,Mingyue Cao et al.
Nianchao Zhang et al.
Objective: Despite extensive research on ulcerative colitis (UC), the mechanisms behind its pathogenesis remain incompletely elucidated. Sanhuang Shu'ai decoction (SSD) has granted attention for its potential therapeutic ...
Elucidating the underlying therapeutic mechanism of Feikang prescription on chronic obstructive pulmonary disease: insights from a comprehensive analysis [0.03%]
阐明肺康方治疗慢性阻塞性肺疾病的作用机制:综合分析视角
Xiaofang Li,Wenjiang Zheng,Zhiyan Luo et al.
Xiaofang Li et al.
Background: Ranking fourth highest mortality rate globally, chronic obstructive pulmonary disease (COPD) exerts a heavy burden on both economies and healthcare systems. The Feikang prescription, a traditional Chinese herb...
Chuanxiong-Renshen medicine pair ameliorates neuroinflammation in Alzheimer's disease through modulation of the PKC-α/NF-κB signaling pathway [0.03%]
芎参配伍通过调节PKC-α/NF-κB信号通路改善阿尔茨海默病的神经炎症作用机制研究
Xiao-Yan Wang,Yuan-Yuan Wang,Jian Zhang et al.
Xiao-Yan Wang et al.
Background and aim: Previous studies have identified Chuanxiong Renshen decoction as a promising anti-Alzheimer's disease (AD) agent, with its brain-penetrating components characterized via UHPLC-MS/MS. This study further...
Buyang huanwu decoction protects against cerebral ischemia-reperfusion injury by inhibiting complement and coagulation cascades: A proteomics and experimental study [0.03%]
补阳还五汤通过抑制补体及凝血级联反应对抗脑缺血再灌注损伤:基于蛋白质组学和实验研究
Yanling Li,Zhongji Hu,Lingli Xie et al.
Yanling Li et al.
Objective: Proteomics Approach to Investigate the Mechanism of Buyang Huanwu Decoction(BYHWD) in Ameliorating Cerebral Ischemia-Reperfusion Injury through Inhibition of Complement and Coagulation Cascade Activation. ...
Baicalin ameliorates high-fat diet induced MAFLD by inhibiting ERK/PPARγ/CD36 pathway [0.03%]
黄芩素通过抑制ERK/PPARγ/CD36信号通路改善高脂诱导的MAFLD病理进展
Jiamin Lei,Xiaohui Wang,Zheng Su et al.
Jiamin Lei et al.
Objective: Metabolic dysfunction-associated fatty liver disease (MAFLD) is a global health concern with limited therapeutic options. Baicalin (BA), a natural flavonoid, has shown promise in ameliorating lipid metabolism a...
Enhancement of skin defense against UVB damage by fermentation of Leonurus japonicus with Saccharomyces cerevisiae [0.03%]
益母草发酵液对皮肤UVB损伤的防护作用研究
Miao-Miao Liu,Zi-Ye Tian,Yi-Mo Wang et al.
Miao-Miao Liu et al.
Background: Leonurus japonicus (Chinese motherwort) is a medicinal plant that is widely used in Asia. The fermentation of plant materials can produce bioactive compounds through a series of biochemical reactions that alte...