Ariel Pradipta,David Virya Chen,Ihsan Fauzan et al.
Ariel Pradipta et al.
Tuberculosis (TB) is currently one of the leading causes of infectious disease deaths globally, and Indonesia ranks 2nd in annual TB cases, below only India. Accurate TB diagnosis and detection of multidrug-resistant TB (MDR-TB) in real-wor...
Genomic insights into Klebsiella pneumoniae: Virulence, resistance, and transmission in South and Southeast Asia [0.03%]
肺炎克雷伯菌的基因组学研究:毒力、耐药性和在南亚和东南亚的传播
Woranich Hinthong,Jody Phelan,Arif Hussain et al.
Woranich Hinthong et al.
Background: Klebsiella pneumoniae has long posed a significant challenge in clinical settings worldwide, particularly due to its carbapenemase production and multidrug-resistant (MDR) characteristics. While extensive geno...
Nanopore-targeted sequencing: A new and effective technique for the diagnosis of non-tuberculous mycobacteria pulmonary disease [0.03%]
纳米孔靶向测序技术在非结核分枝杆菌肺病诊断中的应用及其前景
Li-Ping Cheng,Li Wang,Yun-Fei Wang et al.
Li-Ping Cheng et al.
Non-tuberculous mycobacteria pulmonary disease (NTM-PD) has become a significant public health issue threatening human health in recent years. Traditional mycobacterial culture is complex, time-consuming, and unable to identify NTM at the s...
Helicobacter pylori CagT4SS proteins CagN and CagM bind DNA and CagN is involved in heptose-independent pro-inflammatory substrate translocation by the T4SS [0.03%]
幽门螺杆菌CagT4SS蛋白CagN和CagM结合DNA以及CagN参与T4SS介导的庚糖非依赖性促炎底物转运
Simon H Bats,Felix Metz,Johanna Beilmann et al.
Simon H Bats et al.
The Cag type 4 secretion system (CagT4SS) of Helicobacter pylori is encoded on the cag pathogenicity island (cagPAI) that is present in about 60 % of all strains. It translocates the effector protein CagA, DNA and small bacterial metabolite...
Enteropathogenic Escherichia coli revisited - New insights into old EPEC isolates using whole genome sequencing [0.03%]
再访肠致病性大肠杆菌——采用全基因组测序重新分析旧的EPEC分离株的新见解
Alexander Kehl,Lisa Bader,Agnes C Kaiping et al.
Alexander Kehl et al.
Enteropathogenic E. coli (EPEC) cause severe diarrhoeal disease in children under the age of three in low- and middle-income countries. Upon ingestion of contaminated food or water, the bacteria colonise the small intestine. EPEC are groupe...
From crisis to routine - Standardization of SARS-CoV-2 genome detection by enhanced EQA schemes in a scientific pandemic network [0.03%]
从危机到常规——科研新冠肺炎疫情网络通过增强的EQA方案规范SARS-CoV-2基因组检测标准
Martin Kammel,Hans-Peter Grunert,Anika Zimmermann et al.
Martin Kammel et al.
In the beginning of 2020, the outbreak of the COVID-19 pandemic led to a crisis in which diagnostic methods for the genome detection of SARS-CoV-2 were urgently needed. Based on the very early publication of the basic principles for a diagn...
Occurrence of vanA/vanM-positive vancomycin-resistant Enterococcus faecium in hospital wastewater associated with clinical infections in Guangzhou, China: A genomic epidemiological study [0.03%]
中国广州医疗机构污水中万古霉素耐药粪肠球菌的出现与临床感染的基因组流行病学研究:vanA/vanM阳性分离株分子特征及传播分析
Liling Zhang,Minxuan Su,Shaowei Meng et al.
Liling Zhang et al.
Background: The emerging ST80 vancomycin-resistant Enterococcus faecium (VREfm) lineage, linked to the increases of clinical infections in China and Japan, raises concerns about environmental transmission. Hospital wastew...
Assessing potential misidentification of Staphylococcus argenteus as Staphylococcus aureus in clinical routine samples: A retrospective study [0.03%]
一项回顾性研究:评估临床常规样本中白葡萄球菌误鉴定为金黄色葡萄球菌的潜在可能
Farah Alhussein,Dennis Held,Ahmad Mohamed Mostafa Abdrabou et al.
Farah Alhussein et al.
Staphylococcus argenteus is a recently described member of the Staphylococcus aureus complex. Thus far, its frequency in clinical samples has been rarely described. Following an update of the commercially available matrix-assisted laser des...
Characterization of outer membrane vesicles of Aggregatibacter actinomycetemcomitans serotypes a, b and c and their interactions with human neutrophils [0.03%]
牙龈卟啉单胞菌血清型A、B和C的外膜囊泡及其与人中性粒细胞的相互作用特征化研究
Yanyan Fu,Anke Trautwein-Schult,Sjouke Piersma et al.
Yanyan Fu et al.
Aggregatibacter actinomycetemcomitans (Aa) is a Gram-negative oral pathogen associated with periodontitis and systemic diseases. Seven serotypes of Aa are known, with serotypes a, b and c being most prevalent worldwide. Interestingly, serot...
DDX17 promotes DENV-2 replication via interaction with viral dsRNA and G3BP1 [0.03%]
DDX17通过与病毒dsRNA和G3BP1相互作用促进DENV-2复制
Peijun Han,Wei Ye,Hongwei Ma et al.
Peijun Han et al.
Dengue virus (DENV) is one of the major arboviruses that pose a serious threat to global human health. However, there is currently no specific antiviral drug available for the treatment of DENV infection. DDX17, a member of the DExD/H-box h...