Prevalence, characteristics and clinical features of hypervirulent Klebsiella pneumoniae in a German university hospital [0.03%]
德国大学医院中高毒力肺炎克雷伯菌的流行率、特征和临床表现
Eyüp Doğan,Katharina Schaufler,Stefan E Heiden et al.
Eyüp Doğan et al.
Background: Infections caused by hypervirulent Klebsiella pneumoniae (hvKp) are often characterised by severe, metastatic and relapsing infections. Initially described in Asia, this pathotype has now expanded worldwide. C...
Isolation and characterization of two novel oral bacteriophages with anti-biofilm activity against Cutibacterium acnes [0.03%]
两种新的口腔噬菌体的分离与表征，可针对痤疮丙酸杆菌产生抗生物膜活性
Anja Frantar,Katja Seme,Rok Gašperšič et al.
Anja Frantar et al.
Bacteriophage therapy offers a promising solution to combat antibiotic-resistant infections, yet its potential against biofilm-associated pathogens in oral diseases remains underexplored. This study investigates the opportunistic bacterium ...
Symptomatic Mycoplasma genitalium infections in men who have sex with men and trans women: Should we skip macrolides? [0.03%]
MSM和变性女性中解脲支原体症状感染的治疗：要不要跨过大环内酯类抗生素？
Laura Horvath,Paula Juan,Xènia Lorente et al.
Laura Horvath et al.
Background: Mycoplasma genitalium is an emerging sexually transmitted infection (STI) with increasing antimicrobial resistance, particularly among men who have sex with men (MSM). This study aimed to evaluate the incidenc...
Biofilm-associated Achromobacter xylosoxidans prosthetic valve infective endocarditis [0.03%]
与生物膜相关的木糖氧化产碱菌假体瓣膜感染性心内膜炎
Lisa-Marie Wackernagel,Judith Kikhney,Tassilo Kruis et al.
Lisa-Marie Wackernagel et al.
Background: Infective endocarditis (IE) caused by Gram-negative bacteria is a rare but increasingly recognized emerging infectious disease. Achromobacter xylosoxidans, a Gram-negative non-fermenting opportunistic bacteriu...
Ariel Pradipta,David Virya Chen,Ihsan Fauzan et al.
Ariel Pradipta et al.
Tuberculosis (TB) is currently one of the leading causes of infectious disease deaths globally, and Indonesia ranks 2nd in annual TB cases, below only India. Accurate TB diagnosis and detection of multidrug-resistant TB (MDR-TB) in real-wor...
Genomic insights into Klebsiella pneumoniae: Virulence, resistance, and transmission in South and Southeast Asia [0.03%]
肺炎克雷伯菌的基因组学研究：毒力、耐药性和在南亚和东南亚的传播
Woranich Hinthong,Jody Phelan,Arif Hussain et al.
Woranich Hinthong et al.
Background: Klebsiella pneumoniae has long posed a significant challenge in clinical settings worldwide, particularly due to its carbapenemase production and multidrug-resistant (MDR) characteristics. While extensive geno...
Nanopore-targeted sequencing: A new and effective technique for the diagnosis of non-tuberculous mycobacteria pulmonary disease [0.03%]
纳米孔靶向测序技术在非结核分枝杆菌肺病诊断中的应用及其前景
Li-Ping Cheng,Li Wang,Yun-Fei Wang et al.
Li-Ping Cheng et al.
Non-tuberculous mycobacteria pulmonary disease (NTM-PD) has become a significant public health issue threatening human health in recent years. Traditional mycobacterial culture is complex, time-consuming, and unable to identify NTM at the s...
Helicobacter pylori CagT4SS proteins CagN and CagM bind DNA and CagN is involved in heptose-independent pro-inflammatory substrate translocation by the T4SS [0.03%]
幽门螺杆菌CagT4SS蛋白CagN和CagM结合DNA以及CagN参与T4SS介导的庚糖非依赖性促炎底物转运
Simon H Bats,Felix Metz,Johanna Beilmann et al.
Simon H Bats et al.
The Cag type 4 secretion system (CagT4SS) of Helicobacter pylori is encoded on the cag pathogenicity island (cagPAI) that is present in about 60 % of all strains. It translocates the effector protein CagA, DNA and small bacterial metabolite...
Enteropathogenic Escherichia coli revisited - New insights into old EPEC isolates using whole genome sequencing [0.03%]
再访肠致病性大肠杆菌——采用全基因组测序重新分析旧的EPEC分离株的新见解
Alexander Kehl,Lisa Bader,Agnes C Kaiping et al.
Alexander Kehl et al.
Enteropathogenic E. coli (EPEC) cause severe diarrhoeal disease in children under the age of three in low- and middle-income countries. Upon ingestion of contaminated food or water, the bacteria colonise the small intestine. EPEC are groupe...
From crisis to routine - Standardization of SARS-CoV-2 genome detection by enhanced EQA schemes in a scientific pandemic network [0.03%]
从危机到常规——科研新冠肺炎疫情网络通过增强的EQA方案规范SARS-CoV-2基因组检测标准
Martin Kammel,Hans-Peter Grunert,Anika Zimmermann et al.
Martin Kammel et al.
In the beginning of 2020, the outbreak of the COVID-19 pandemic led to a crisis in which diagnostic methods for the genome detection of SARS-CoV-2 were urgently needed. Based on the very early publication of the basic principles for a diagn...