Functional profiling of CHAP domain-containing peptidoglycan hydrolases of Staphylococcus aureus USA300 uncovers potential targets for anti-staphylococcal therapies [0.03%]
金黄色葡萄球菌USA300型肽聚糖水解酶的CHAP结构域功能谱系分析发现了潜在的抗葡萄球菌疗法目标
Min Wang,Xiaofang Li,Francis M Cavallo et al.
Min Wang et al.
The bacterial pathogen Staphylococcus aureus employs a thick cell wall for protection against physical and chemical insults. This wall requires continuous maintenance to ensure strength and barrier integrity, but also to permit bacterial gr...
Identification and characterization of Staphylococcus argenteus from Indonesia [0.03%]
来自印度尼西亚的表型变异葡萄球菌鉴定及特征分析
Indri Rooslamiati Supriadi,Dewi Santosaningsih,Nyoman S Budayanti et al.
Indri Rooslamiati Supriadi et al.
Background: In 2015, Staphylococcus argenteus was reported for the first time as a novel species of the Staphylococcus aureus complex. While S. argenteus has been found in many countries, its presence in Indonesia has not...
Real-time application of ITS and D1-D3 nanopore amplicon metagenomic sequencing in fungal infections: Enhancing fungal infection diagnostics [0.03%]
实时应用ITS和D1-D3纳米孔扩增子宏基因组测序技术于真菌感染：增强真菌感染诊断能力
Seondeuk Kim,Narae Kim,Wan Beom Park et al.
Seondeuk Kim et al.
While fungal infections cause considerable morbidity and mortality, the performance of the current diagnostic tests for fungal infection is low. Even though fungal metagenomics or targeted next-generation sequencing have been investigated f...
Clinical characteristics of community-onset Clostridioides difficile infections at a tertiary hospital in mainland China: A fourteen-year (2010-2023) retrospective study [0.03%]
中国大陆一家三级医院社区获得性难辨梭状芽胞杆菌感染的临床特征：一项十四年（2010-2023）回顾性研究
Xinrong Jiang,Junyu Bian,Tao Lv et al.
Xinrong Jiang et al.
Background: Clostridioides difficile infection (CDI) is an increasingly common disease in healthcare facilities and community settings. However, there are limited reports of community-onset CDI (CO-CDI) in China. ...
Evolution of mutations in the ftsI gene leading to amino acid substitutions in PBP3 in Haemophilus influenzae strains under the selective pressure of ampicillin and cefuroxime [0.03%]
在氨苄西林和头孢呋辛的作用下，流感嗜血杆菌ftsI基因发生突变及其编码的PBP3蛋白氨基酸位点替换的演变规律研究
Vladislav Jakubu,Iveta Vrbova,Ibrahim Bitar et al.
Vladislav Jakubu et al.
Background: Aminopenicillins are recommended agents for non-invasive Haemophilus influenzae infections. One of the mechanisms of resistance to β-lactams is the alteration of the transpeptidase region of penicillin bindin...
Enteroaggregative Escherichia coli: Frequent, yet underdiagnosed pathotype among E. coli O111 strains isolated from children with gastrointestinal disorders in the Czech Republic [0.03%]
聚集黏附型大肠杆菌：捷克患有胃肠疾病的儿童中EcoliO111菌株的常见类型，但未得到充分诊断
Klára Schlosserová,Ondřej Daniel,Klára Labská et al.
Klára Schlosserová et al.
Enteroaggregative Escherichia coli (EAEC) strains including those of serogroup O111 are important causes of diarrhea in children. In the Czech Republic, no information is available on the etiological role of EAEC in pediatric diarrhea due t...
Uncovering the mechanisms of host mitochondrial cardiolipin release in syphilis: Insights from human microvascular endothelial cells [0.03%]
梅毒病原体触发的人内皮细胞线粒体脂质释放机制及其对神经病理学的影响
Xi Luo,Xiaoyuan Xie,Litian Zhang et al.
Xi Luo et al.
The release of host mitochondrial cardiolipin is believed to be the main factor that contributes to the production of anti-cardiolipin antibodies in syphilis. However, the precise mechanism by which mitochondria release cardiolipin in this ...
An induced mutation of ABC-transporter component VraF(K84E) contributes to vancomycin resistance and virulence in Staphylococcus aureus strain MW2 [0.03%]
金黄色葡萄球菌MW2中一种ABC转运蛋白组分VraF(K84E)突变体有助于万古霉素抗性和毒力
Ruobing Cao,Huimin Su,Zichun Wei et al.
Ruobing Cao et al.
Staphylococcus aureus is a notorious pathogen responsible for various severe diseases. Due to the emergence of drug-resistant strains, the prevention and treatment of S. aureus infections have become increasingly challenging. Vancomycin is ...
Identification and characterization of a novel α-haemolytic streptococci, Streptococcus parapneumoniae sp. nov., which caused bacteremia with pyelonephritis [0.03%]
链球菌肺炎新种(parapneumonia)鉴定及其致败血症并发肾盂肾炎的特性分析
Yuri Katayama,Masatomo Morita,Bin Chang et al.
Yuri Katayama et al.
Objectives: We report a case of bacteremia with pyelonephritis in an adult male with an underlying disease caused by α-hemolytic streptococci. α-Hemolytic streptococci were isolated from blood, but it was challenging to...
Prevalence and characterization of community-associated Staphylococcus aureus isolates from human mastitis in Beijing, China [0.03%]
中国北京地区人乳头炎中社区相关型金黄色葡萄球菌的分离与鉴定
Jihong Gu,Mengyuan Xiong,Jing Zhang et al.
Jihong Gu et al.
Objectives: Staphylococcus aureus (S. aureus) spreads worldwide and occurrence of mastitis caused by it holds significant implications for public health. We aim to reveal the molecular typing, antibiotic resistance and vi...