Biochemical characterization of the Helicobacter pylori Cag Type 4 Secretion System protein CagN and its interaction partner CagM [0.03%]
幽门螺杆菌Cag IV型分泌系统蛋白CagN及其相互作用伙伴CagM的生化特性分析
Simon H Bats,Célia Bergé,Nina Coombs et al.
Simon H Bats et al.
Highly virulent Helicobacter pylori strains contain the cag pathogenicity island (cagPAI). It codes for about 30 proteins forming a type IV secretion system (T4SS) which translocates the pro-inflammatory protein CagA into epithelial host ce...
Non-Tuberculous Mycobacteria multispecies biofilms in cystic fibrosis: development of an in vitro Mycobacterium abscessus and Pseudomonas aeruginosa dual species biofilm model [0.03%]
囊胞分枝杆菌物种生物被膜与囊性纤维化：体外分枝杆菌和绿脓杆菌双菌种生物被膜模型的建立
Graciela Rodríguez-Sevilla,Marta García-Coca,David Romera-García et al.
Graciela Rodríguez-Sevilla et al.
Lung disease in cystic fibrosis (CF) is characterized by the progressive colonization of the respiratory tract by different bacteria, which develop polymicrobial biofilms. In the past decades, there has been an increase in the number of CF ...
Cyclophilin A is the potential receptor of the Mycoplasma genitalium adhesion protein [0.03%]
柠檬酸肽素A是解脲支原体黏附蛋白的受体候选分子
Xiangying Deng,Pei Dai,Minjun Yu et al.
Xiangying Deng et al.
The Mycoplasma genitalium adhesion protein (MgPa), the most important outer membrane protein of M. genitalium, plays a vital role in the adhesion to and invasion of host cells by M. genitalium. Identification of MgPa receptors will help elu...
Multitalented EspB of enteropathogenic Escherichia coli (EPEC) enters cells autonomously and induces programmed cell death in human monocytic THP-1 cells [0.03%]
致病性大肠杆菌(EPEC)多才多艺的EspB蛋白能够自主进入细胞并诱导人类单核THP-1细胞程序化死亡
Doreen Baumann,Helen Salia,Lilo Greune et al.
Doreen Baumann et al.
Enteropathogenic Escherichia coli (EPEC) subvert host cell signaling pathways by injecting effector proteins via a Type 3 Secretion System (T3SS). The T3SS-dependent EspB protein is a multi-functional effector protein, which contributes to ...
Stress-associated endoplasmic reticulum protein 1 (SERP1) and Atg8 synergistically regulate unfolded protein response (UPR) that is independent on autophagy in Candida albicans [0.03%]
压力相关内质网蛋白1（SERP1）和Atg8协同调节Candida albicans中独立于自噬的未折叠蛋白数目反应（UPR）
Jianrong Li,Qilin Yu,Bing Zhang et al.
Jianrong Li et al.
Cellular stresses could activate several response processes, such as the unfolded protein response (UPR), autophagy and oxidative stress response to restore cellular homeostasis or render cell death. Herein, we identified the Candida albica...
V Hoerr,M Franz,M W Pletz et al.
V Hoerr et al.
Infective endocarditis (IE) is a life-threatening disease, caused by septic vegetations and inflammatory foci on the surface of the endothelium and the valves. Due to its complex and often indecisive presentation the mortality rate is still...
Staphylococcus aureus in the airways of cystic fibrosis patients - A retrospective long-term study [0.03%]
囊性纤维化患者气道中的金黄色葡萄球菌长期回顾性研究
Mathias Schwerdt,Claudia Neumann,Bianca Schwartbeck et al.
Mathias Schwerdt et al.
Background: Cystic fibrosis (CF) is an autosomal recessive disease associated with chronic airway infections by Staphylococcus aureus as one of the earliest and most prevalent pathogens. We conducted a retrospective study...
Juliane Hoyer,Jürgen Bartel,Alejandro Gómez-Mejia et al.
Juliane Hoyer et al.
Iron is an essential trace element and involved in various key metabolic pathways in bacterial lifestyle. Within the human host, iron is extremely limited. Hence, the ability of bacteria to acquire iron from the environment is critical for ...
Genomic and phenotypic diversity of Clostridium difficile during long-term sequential recurrences of infection [0.03%]
艰难梭菌感染长期反复过程中的基因组和表型多样性研究
F E Sachsenheimer,I Yang,O Zimmermann et al.
F E Sachsenheimer et al.
Infection with the emerging pathogen Clostridioides (Clostridium) difficile might lead to colonization of the gastrointestinal tract of humans and mammals eventually resulting in antibiotic-associated diarrhea, which can be mild to possibly...
Molecular characterization, toxin detection and resistance testing of human clinical Clostridium difficile isolates from Lebanon [0.03%]
黎巴嫩人类临床艰难梭菌分离株的分子特征、毒素检测及耐药性试验
Fabian K Berger,Sari S Rasheed,George F Araj et al.
Fabian K Berger et al.
Clostridium (Clostridioides) difficile is the main cause for nosocomial diarrhoea in industrialised nations. Epidemiologic data on the pathogen's occurrence in other world regions are still scarce. In this context we characterized with phen...