Enterohemorrhagic Escherichia coli O157 outer membrane vesicles induce interleukin 8 production in human intestinal epithelial cells by signaling via Toll-like receptors TLR4 and TLR5 and activation of the nuclear factor NF-κB [0.03%]
致病性大肠杆菌O157外膜囊泡通过Toll样受体TLR4和TLR5信号转导及活化核因子NF-κB诱导人肠上皮细胞产生白介素8
Martina Bielaszewska,Monika Marejková,Andreas Bauwens et al.
Martina Bielaszewska et al.
Proinflammatory cytokines play important roles in the pathogenesis of diseases caused by enterohemorrhagic Escherichia coli (EHEC) O157, but the spectrum of bacterial components involved in the proinflammatory responses is not fully underst...
The mpn668 gene of Mycoplasma pneumoniae encodes a novel organic hydroperoxide resistance protein [0.03%]
肺炎支原体的mpn668基因编码一个新的有机过氧化氢抗性蛋白
Lie-Song Chen,Chun Li,Xiao-Xing You et al.
Lie-Song Chen et al.
Mycoplasma pneumoniae (M. pneumoniae), as an obligate parasite, has evolved a protective strategy for coping with oxidative challenges caused by M. pneumoniae itself as well as the host immune system. However, to date, few antioxidant enzym...
Genetic characterization of Shiga toxin producing Escherichia coli belonging to the emerging hybrid pathotype O80:H2 isolated from humans 2010-2017 in Switzerland [0.03%]
2010-2017年从人类中分离的新型杂合型O80:H2血清型的大肠杆菌O157分离株的基因特征
Magdalena Nüesch-Inderbinen,Nicole Cernela,Daniel Wüthrich et al.
Magdalena Nüesch-Inderbinen et al.
Shiga toxin-producing E. coli (STEC) O80:H2 is an uncommon hybrid pathotype that has recently emerged in France. We analysed 18 STEC O80:H2 isolated from humans in Switzerland during 2010-2017. All isolates carried stx2a or stx2d, the rare ...
Shiga toxin-producing Escherichia coli O103:H2 outbreak in Germany after school trip to Austria due to raw cow milk, 2017 - The important role of international collaboration for outbreak investigations [0.03%]
德国学校赴奥地利旅行后爆发肠出血性大肠杆菌O103:H2型感染疫情与生奶有关——国际协作在疫情调查中的重要作用
Maren Mylius,Johannes Dreesman,Matthias Pulz et al.
Maren Mylius et al.
Following a school ski-trip to Austria from 10 to 18/02/2017, nine of 25 participants of the group from Lower Saxony (Germany) developed gastroenteritis. The students and teachers (17-41 years) shared meals in a hotel. Active case finding r...
The emergence of Clostridium difficile PCR ribotype 078 in piglets in the Czech Republic clusters with Clostridium difficile PCR ribotype 078 isolates from Germany, Japan and Taiwan [0.03%]
捷克共和国猪let中艰难梭菌PCR亲和型078的出现与来自德国、日本和中国台湾的艰难梭菌PCR亲和型078分离株聚类在一起
Marcela Krutova,Monika Zouharova,Jana Matejkova et al.
Marcela Krutova et al.
Clostridium difficile is a major nosocomial pathogen in humans with an increasing incidence in the community. The "one-health" approach of research is needed to investigate possible reservoirs of C. difficile and route of its transmission. ...
Staphylococcus aureus requires less virulence to establish an infection in diabetic hosts [0.03%]
耐糖耐药表皮葡萄球菌需要较少的毒力即可在糖尿病宿主体内引起感染
Lorena Tuchscherr,Èva Korpos,Hélène van de Vyver et al.
Lorena Tuchscherr et al.
Staphylococcus aureus is the most frequent pathogen causing diabetic foot infections. Here, we investigated the degree of bacterial virulence required to establish invasive tissue infections in diabetic organisms. Staphylococcal isolates fr...
Claus Østergaard,Jens Kjølseth Møller
Claus Østergaard
Outbreak investigations demand a fast and discriminative typing method. MALDI-TOF MS has been shown to be a rapid, easy and inexpensive method of subtyping MRSA.The aim of the present study is to explore whether it is possible to subdivide ...
HopQ impacts the integrin α5β1-independent NF-κB activation by Helicobacter pylori in CEACAM expressing cells [0.03%]
HopQ通过CEACAM表达细胞影响Helicobacter pylori介导的整合素α5β1独立的NF-κB活化作用
Michael Hartmut Feige,Olga Sokolova,Anna Pickenhahn et al.
Michael Hartmut Feige et al.
Helicobacter pylori infection persists in more than half of the world's population and represents a risk factor for peptic ulcer disease and gastric cancer. Virulent strains of H. pylori carry a cag pathogenicity island (cagPAI), which enco...
Eric Banan-Mwine Daliri,Charles Nkufi Tango,Byong H Lee et al.
Eric Banan-Mwine Daliri et al.
The human gut microbiome consists of many bacteria which are in symbiotic relationship with human beings. The gut microbial metabolism, as well as the microbial-host co-metabolism, has been found to greatly influence health and disease. Fac...
Detection of methicillin-resistant coagulase-negative staphylococci harboring the class A mec complex by MALDI-TOF mass spectrometry [0.03%]
应用基质辅助激光解析电离飞行时间质谱技术检测携带A类mec复合物的耐甲氧西林凝固酶阴性葡萄球菌
Dominik Schuster,Michaele Josten,Kathrin Janssen et al.
Dominik Schuster et al.
The aim of this study was to test the identification of methicillin resistance in coagulase-negative staphylococci by routine matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS). SCCmec cassettes of t...