Pseudomonas aeruginosa quorum sensing molecule N-3-oxo-dodecanoyl-l-homoserine lactone activates human platelets through intracellular calcium-mediated ROS generation [0.03%]
铜绿假单胞菌群体感应分子N-3-氧代月桂酰高丝氨酸乳酸INT通过细胞内钙介导的ROS生成活化人类血小板
Vivek Kumar Yadav,Pradeep Kumar Singh,Manmohit Kalia et al.
Vivek Kumar Yadav et al.
Pseudomonas aeruginosa, an opportunistic pathogen release N-3-oxo-dodecanoyl-l-homoserine lactone (3-oxo-C12HSL) and N-butyryl-l-homoserine lactone (C4-HSL) quorum sensing (QS) molecules to regulate various virulence factors responsible for...
Regulation of virulence and motility by acetate in enteropathogenic Escherichia coli [0.03%]
乙酸对致病性大肠杆菌毒力和运动性的调节作用
Fan Yang,Lei Yang,Zhanhe Chang et al.
Fan Yang et al.
Enteropathogenic Escherichia coli colonizes the human small intestine and causes severe diarrhea. Short-chain fatty acids are abundant in the intestine owing to the metabolic activity of the microflora and are important for intestinal healt...
P27 (MBOV_RS03440) is a novel fibronectin binding adhesin of Mycoplasma bovis [0.03%]
牛支原体的新FN结合粘附素P27(MBOV_RS03440)
Xi Chen,Jing Huang,Hongmei Zhu et al.
Xi Chen et al.
Mycoplasma bovis, one of the major pathogens of bovine respiratory disease, binds to respiratory epithelial cells resulting in severe pneumonia and tissue damage. This study was designed to identify the adhesive function of a putative 27-kD...
Shiga toxin 2a binds antithrombin and heparin, but does not directly activate platelets [0.03%]
志贺毒素2a可与抗凝血酶和肝素结合，但不会直接活化血小板
Ludwig Knabl,Michael Berktold,Osama A Hamad et al.
Ludwig Knabl et al.
Escherichia coli-induced hemolytic uremic syndrome (eHUS) is a life-threatening complication of infection with Shiga toxin (Stx), in particular Stx2a-producing Escherichia coli. Enhanced coagulation activation with formation of microthrombi...
Secretory organelle trafficking in Toxoplasma gondii: A long story for a short travel [0.03%]
托拉川虫-secretory organelle trafficking in Toxoplasma gondii: A long story for a short travel
Kannan Venugopal,Sabrina Marion
Kannan Venugopal
Toxoplasma gondii (T. gondii) possesses a highly polarized secretory system, which efficiently assembles de novo micronemes (MIC) and rhoptries (ROP) during parasite replication. Pioneer works have studied the sorting motifs within MIC and ...
Core elements of the vegetative replication control of the Inc1 plasmid pO104_90 of Escherichia coli O104:H4 also regulate its transfer frequency [0.03%]
志贺毒素大肠杆菌O104∶H4的Inc1质粒pO104_90复制控制中的核心元件也调节其转移频率
Michael Berger,Petya Berger,Erick Denamur et al.
Michael Berger et al.
The highly virulent Escherichia coli O104:H4 isolate that caused a large outbreak in 2011 carries three plasmids. Out of these, only one, the IncI plasmid pO104_90 that encodes two extended spectrum beta-lactamases, can transfer itself by c...
Capsule and fimbriae modulate the invasion of Haemophilus influenzae in a human blood-cerebrospinal fluid barrier model [0.03%]
肺炎嗜血杆菌胶囊和菌毛的结构调节其在人血液-脑脊液屏障模型中的侵袭力
Svenja Häuser,Christian Wegele,Carolin Stump-Guthier et al.
Svenja Häuser et al.
The Gram-negative bacterium Haemophilus influenzae (H. influenzae) can commensally colonize the upper respiratory tract, but also cause life threatening disease including epiglottitis, sepsis and meningitis. The H. influenzae capsule protec...
Serotypes and virulence profiles of Shiga toxin-producing Escherichia coli strains isolated during 2017 from human infections in Switzerland [0.03%]
2017年分离自瑞士人类感染的产志贺毒素的大肠杆菌菌株的血清型和毒力谱型
Magdalena Nüesch-Inderbinen,Marina Morach,Nicole Cernela et al.
Magdalena Nüesch-Inderbinen et al.
Since 2015, the Swiss Federal Office of Public Health registered an increase of notifications of STEC, probably due to the adoption of culture independent stx screening tests in diagnostic laboratories. This study aimed to identify the sero...
Ureaplasma spp. lipid-associated membrane proteins induce human monocyte U937 cell cycle arrest through p53-independent p21 pathway [0.03%]
解脲支原体脂膜蛋白通过p53非依赖性p21途径诱导人单核U937细胞周期停滞
Xucheng Huang,Yingli Qiao,Yixuan Zhou et al.
Xucheng Huang et al.
Ureaplasma spp. are known to be associated with human genitourinary tract diseases and perinatal diseases and Ureaplasma spp. Lipid-associated membrane proteins (LAMPs) play important roles in their related diseases. However, the exact mech...
Evolution of STEC virulence: Insights from the antipredator activities of Shiga toxin producing E. coli [0.03%]
志贺毒素大肠杆菌的抗捕食者活性对STEC毒力进化所给的启示
Gerald B Koudelka,Jason W Arnold,Dolonchapa Chakraborty
Gerald B Koudelka
Shiga toxin-producing Escherichia coli (STEC) are a diverse group of strains that are implicated in over 270,000 cases of human illness annually in the United States alone. Shiga toxin (Stx), encoded by a resident temperate lambdoid bacteri...