Unveiling the early events of Pseudomonas aeruginosa adaptation in cystic fibrosis airway environment using a long-term in vitro maintenance [0.03%]
基于体外长期培养技术揭示铜绿假单胞菌在囊性纤维化气道微环境中早期定植适应事件
Ana Margarida Sousa,Rosana Monteiro,Maria Olívia Pereira
Ana Margarida Sousa
Pseudomonas aeruginosa chronic infections are the major cause of high morbidity and mortality in cystic fibrosis (CF) patients due to the use of sophisticated mechanisms of adaptation, including clonal diversification into specialized CF-ad...
De-O-Acetylation of mucin-derived sialic acids by recombinant NanS-p esterases of Escherichia coli O157:H7 strain EDL933 [0.03%]
大肠杆菌O157:H7菌株EDL933重组NanS-p酯酶对黏蛋白来源唾液酸的去O-乙酰基作用
S Feuerbaum,N Saile,G Pohlentz et al.
S Feuerbaum et al.
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 strain EDL933 encodes the single chromosomal 9-O-acetylesterase NanS, and several copies of prophage-encoded 9-O-acetylesterases (NanS-p). These enzymes have recently been shown to cleave 5-...
Anti-inflammatory agents reduce microglial response, demyelinating process and neuronal toxin uptake in a model of encephalopathy produced by Shiga Toxin 2 [0.03%]
抗炎剂可通过减少肠出血性大肠杆菌溶血素2型所致脑病模型中的小胶质细胞反应、脱髓鞘过程和神经元毒性物质摄取来发挥治疗作用
Alipio Pinto,Clara Berdasco,David Arenas-Mosquera et al.
Alipio Pinto et al.
Infections by Enterohemorrhagic Escherichia coli may cause in addition to hemolytic uremic syndrome neurological disorders which may lead to fatal outcomes in patients. The brain striatum is usually affected during this outcome. The aim of ...
Sebastian Suerbaum
Sebastian Suerbaum
Comparative analyses of biofilm formation among different Cutibacterium acnes isolates [0.03%]
不同痤疮丙酸杆菌菌株生物被膜形成能力的比较分析
Torben Kuehnast,Fatih Cakar,Theresa Weinhäupl et al.
Torben Kuehnast et al.
The Gram-positive anaerobic bacterium Cutibacterium acnes is a commensal of the human skin, but also an opportunistic pathogen that contributes to the pathophysiology of the skin disease acne vulgaris. Moreover, C. acnes, in addition to oth...
Effect of chlorine on cultivability of Shiga toxin producing Escherichia coli (STEC) and β-lactamase genes carrying E. coli and Pseudomonas aeruginosa [0.03%]
氯离子对产志贺毒素的大肠杆菌和β-内酰胺酶基因携带大肠杆菌及绿脓杆菌培养效果的影响
Anni Bommer,Olga Böhler,Eva Johannsen et al.
Anni Bommer et al.
The worldwide spread of toxin-producing and multi-drug resistant bacteria in water, food and the environment is considered a major threat to human health. Drinking water quality is controlled by inspection of fecal indicators presence where...
Petting zoos as sources of Shiga toxin-producing Escherichia coli (STEC) infections [0.03%]
接触型动物园中志贺毒素大肠杆菌(STEC)感染的来源
Sabine Schlager,Sarah Lepuschitz,Werner Ruppitsch et al.
Sabine Schlager et al.
Despite their general low incidence, Shiga toxin-producing Escherichia (E.) coli (STEC) infections are considered an important public health issue due to the severity of illness that can develop, particularly in young children. We report on...
Strength of the association between antibiotic use and hemolytic uremic syndrome following Escherichia coli O157:H7 infection varies with case definition [0.03%]
抗生素使用与O157:H7感染后的溶血性尿毒综合征之间关联强度取决于病例定义
Gillian A M Tarr,Hanna N Oltean,Amanda I Phipps et al.
Gillian A M Tarr et al.
Background: The veracity of the association between antibiotic use and hemolytic uremic syndrome (HUS) caused by Escherichia coli O157:H7 has been a topic of debate. We postulated that criteria used to define HUS affect t...
Essential role of the ESX-3 associated eccD3 locus in maintaining the cell wall integrity of Mycobacterium smegmatis [0.03%]
Mycobacterium smegmatis 细胞壁完整性的维持与ESX-3相关eccD3位点密切相关
Yutika Nath,Suvendra Kumar Ray,Alak Kumar Buragohain
Yutika Nath
Mycobacterial pathogens have evolved a unique secretory apparatus called the Type VII secretion system (T7SS) which comprises of five gene clusters designated as ESX1, ESX2, ESX3, ESX4, and ESX5. Of these the ESX3 T7SS plays an important ro...
Shiga toxin-glycosphingolipid interaction: Status quo of research with focus on primary human brain and kidney endothelial cells [0.03%]
雪卡毒素-糖脂相互作用：以原代人类脑和肾内皮细胞为重点的研究现状
Nadine Legros,Gottfried Pohlentz,Daniel Steil et al.
Nadine Legros et al.
Shiga toxin (Stx)-mediated injury of the kidneys and the brain represent the major extraintestinal complications in humans upon infection by enterohemorrhagic Escherichia coli (EHEC). Damage of renal and cerebral endothelial cells is the ke...