Genomic investigation of a sequence type 67 Clostridium difficile causing community-acquired fulminant colitis in Hong Kong [0.03%]
香港社区获得性中毒性巨结肠艰难梭菌序列型67的基因组学研究
Huiluo Cao,Sally Cheuk-Ying Wong,Wing-Cheong Yam et al.
Huiluo Cao et al.
In 2017, we identified a Clostridium difficile strain HKCD4 that caused community-acquired fulminant colitis in a previously healthy child. Phylogenetically, it belonged to clade 2, sequence type 67 and was resistant to fluoroquinolone and ...
Effect of amyloid curli fibrils and curli CsgA monomers from Escherichia coli on in vitro model of intestinal epithelial barrier stimulated with cytokines [0.03%]
大肠杆菌淀粉样粘附素纤维丝及CsgA单体对细胞因子刺激的小肠上皮屏障模型的影响
Beata Sobieszczańska,Barbara Pawłowska,Anna Duda-Madej et al.
Beata Sobieszczańska et al.
Amyloid curli fibrils produced by Escherichia coli are well-known virulence factor influencing E. coli adhesion and biofilm formation. However, the impact of curli on intestinal epithelial barrier stimulated with proinflammatory cytokines i...
Interplay of plant glycan hydrolases and LysM proteins in plant-Bacteria interactions [0.03%]
植物甘露聚糖水解酶和LysM蛋白在植物-细菌互作中的相互作用关系研究
Maria A Schlöffel,Christoph Käsbauer,Andrea A Gust
Maria A Schlöffel
Plants are always found together with bacteria and other microbes. Although plants can be attacked by phytopathogenic bacteria, they are more often engaged in neutral or mutualistic bacterial interactions. In the soil, plants associate with...
Enhanced microbiological surveillance reveals that temporal case clusters contribute to the high rates of campylobacteriosis in a model agroecosystem [0.03%]
改良型微生物监测显示，在一个模型农业生态系统中时间性病例群集导致了空肠弯曲菌感染的高发病率
G Douglas Inglis,Valerie F Boras,Andrew L Webb et al.
G Douglas Inglis et al.
Infections by pathogenic Campylobacter species were determined in diarrheic (n = 2,217) and non-diarrheic control (n = 104) people in Southwestern Alberta (SWA), Canada over a 1-year period using specialized and conventional isolation, and ...
A small non-coding RNA facilitates Brucella melitensis intracellular survival by regulating the expression of virulence factor [0.03%]
一种小的非编码RNA通过调节毒力因子的表达来促进布鲁氏菌的胞内生存能力
Yufei Wang,Yuehua Ke,Cuijuan Duan et al.
Yufei Wang et al.
Brucella species are the causative agents of brucellosis, a worldwide zoonotic disease that affects a broad range of mammals and causes great economic losses. Small regulatory RNAs (sRNAs) are post-transcriptional regulatory molecules that ...
Porin loss in Klebsiella pneumoniae clinical isolates impacts production of virulence factors and survival within macrophages [0.03%]
肺炎克雷伯菌临床分离株的孔蛋白丢失影响毒力因子产生及巨噬细胞内存活能力
Debra N Brunson,Emir Maldosevic,Amanda Velez et al.
Debra N Brunson et al.
Clinical isolates of Klebsiella pneumoniae are often resistant to beta-lactam antibiotics via the acquisition of extended spectrum beta lactamase (ESBL) enzymes paired with loss of one or both major outer membrane porins. It has been well e...
Comprehensive proteomic analysis and pathogenic role of membrane vesicles of Listeria monocytogenes serotype 4b reveals proteins associated with virulence and their possible interaction with host [0.03%]
全面的蛋白质组分析及致病性研究显示鼠伤寒沙门氏菌4b型菌株膜囊泡中与毒力相关的蛋白及其可能与宿主的相互作用
Raman Karthikeyan,Pratapa Gayathri,Paramasamy Gunasekaran et al.
Raman Karthikeyan et al.
Membrane vesicles (MVs) are produced by various Gram positive and Gram negative pathogenic bacteria and play an important role in virulence. In this study, the membrane vesicles (MVs) of L. monocytogenes were isolated from the culture super...
In search of a function for the membrane anchors of class IIIa adenylate cyclases [0.03%]
寻找第三类腺苷酸环化酶膜锚的作用功能
Manuel Finkbeiner,Julia Grischin,Anubha Seth et al.
Manuel Finkbeiner et al.
Nine pseudoheterodimeric mammalian adenylate cyclases possess two dissimilar hexahelical membrane domains (TM1 and TM2), two dissimilar cyclase-transducing-elements (CTEs) and two complementary catalytic domains forming a catalytic dimer (o...
Secreted proteases: A new insight in the pathogenesis of extraintestinal pathogenic Escherichia coli [0.03%]
分泌型蛋白酶在肠外致病性大肠杆菌感染中的作用及机制研究的新进展
Rima Tapader,Sulagna Basu,Amit Pal
Rima Tapader
Bacterial secreted proteases are the key factors that increase the virulence potential of different pathogens. Extraintestinal pathogenic E. coli (ExPEC) is a distinct pathotype that has unique ability to infect various body sites apart fro...
Evolution of Klebsiella pneumoniae with mucoid and non-mucoid type colonies within a single patient [0.03%]
肺炎克雷伯菌单个患者分离株的黏液和非黏液表型的演变规律分析
Haejeong Lee,Juyoun Shin,Yeun-Jun Chung et al.
Haejeong Lee et al.
We obtained nine Klebsiella pneumoniae isolates successively isolated from a single patient. Four pairs (M1-M4 and NM1-NM4) obtained simultaneously from the same site showed different colony types, mucoid and non-mucoid, while the final iso...