Christoph M Ernst,Andreas Peschel
Christoph M Ernst
Daptomycin has become an important antibiotic for the treatment of serious Methicillin-Resistant Staphylococcus aureus (MRSA) infections. Unlike other approved antibiotics, its mode of action is still under active investigation, as well as ...
Bacterial adhesion and host cell factors leading to effector protein injection by type III secretion system [0.03%]
III型分泌系统效应蛋白注入的细菌黏附和宿主细胞因素
Erwin Bohn,Michael Sonnabend,Kristina Klein et al.
Erwin Bohn et al.
Type III secretion systems (T3SS) play a crucial role for virulence in many Gram-negative bacteria. After tight bacterial contact to host cells, the T3SS injects effector proteins into the host cells, which leads to cell invasion, tissue de...
Type I interferon induced by TLR2-TLR4-MyD88-TRIF-IRF3 controls Mycobacterium abscessus subsp. abscessus persistence in murine macrophages via nitric oxide [0.03%]
由TLR2-TLR4-MyD88-TRIF-IRF3诱导的I型干扰素通过一氧化氮控制小鼠巨噬细胞中Mycobacterium abscessus subsp. abscessus的持续存在
Nanthapon Ruangkiattikul,Doris Rys,Ketema Abdissa et al.
Nanthapon Ruangkiattikul et al.
Mycobacterium abscessus (MAB) is an emerging, rapidly growing non-tuberculous Mycobacterium causing therapy-resistant pulmonary disease especially in patients with cystic fibrosis (CF). Smooth and rough colony type MAB can be isolated from ...
Biogenesis and function of the autotransporter adhesins YadA, intimin and invasin [0.03%]
自转运位黏附分子YadA、intimin和invasin的生物发生及其功能
Karolin Leibiger,Jonas Malte Schweers,Monika Schütz
Karolin Leibiger
Bacteria often express numerous virulence factors. These virulence factors make them successful pathogens, by e.g. mediating attachment to host cells and thereby facilitating persistence or invasion, or by contributing to the evasion of the...
L Thoma,B Vollmer,F Oesterhelt et al.
L Thoma et al.
Time-lapse imaging of conjugative plasmid transfer in Streptomyces revealed intriguing insights into the unique two-step conjugation process of this Gram+ mycelial soil bacterium. Differentially labelling of donor and recipient strains with...
IP-10 contributes to the inhibition of mycobacterial growth in an ex vivo whole blood assay [0.03%]
IP-10通过体外全血实验参与抑制结核分枝杆菌生长的作用
Ivana Palucci,Basem Battah,Alessandro Salustri et al.
Ivana Palucci et al.
Interferon-γ inducible protein 10 (IP-10), is a potent chemoattractant that promotes migration of monocytes and activated T-cells to inflammation foci. IP-10 is elevated in serum of patients with chronic hepatitis C virus (HCV) and tubercu...
Franziska Wiker,Nils Hauck,Stephanie Grond et al.
Franziska Wiker et al.
Cell wall biosynthesis represents a valid target for antibacterial action but only a limited number of chemical structure classes selectively interact with specific enzymes or protein structures like transporters of the cell envelope. The i...
Roles of DevBCA-like ABC transporters in the physiology of Anabaena sp. PCC 7120 [0.03%]
类DevBCA型ABC转运蛋白在鱼腥藻生理学中的作用
Dmitry Shvarev,Iris Maldener
Dmitry Shvarev
The filamentous, photosynthetic cyanobacterium Anabaena sp. PCC 7120 can be considered as a true multicellular bacterium. Along the filament of cells, nitrogen fixation is spatially separated from the incompatible process of oxygenic photos...
Formylated N-terminal methionine is absent from the Mycoplasma hyopneumoniae proteome: Implications for translation initiation [0.03%]
猪肺炎支原体蛋白质组中不存在甲酰化N端甲硫氨酸：对翻译起始的影响
Veronica M Jarocki,Joel R Steele,Michael Widjaja et al.
Veronica M Jarocki et al.
N-terminal methionine excision (NME) is a proteolytic pathway that cleaves the N-termini of proteins, a process that influences where proteins localise in the cell and their turnover rates. In bacteria, protein biosynthesis is initiated by ...
The prevalence of Staphylococcus aureus with mucoid phenotype in the airways of patients with cystic fibrosis-A prospective study [0.03%]
铜绿假单胞菌以外的主要气道定植菌株——前瞻性研究
Farina E Lennartz,Bianca Schwartbeck,Angelika Dübbers et al.
Farina E Lennartz et al.
Background: Staphylococcus aureus is one of the most frequently isolated pathogens in the respiratory tract of CF patients. Recently, we characterized peculiar mucoid S. aureus isolates, which are excessive biofilm former...