Lactobacillus plantarum CBT LP3 ameliorates colitis via modulating T cells in mice [0.03%]
植物乳杆菌CBT LP3通过调节小鼠T细胞改善结肠炎
Da Hye Kim,Soochan Kim,Jae Bum Ahn et al.
Da Hye Kim et al.
Lactobacillus plantarum has been identified as a probiotic bacterium owing to its role in immune regulation and maintenance of intestinal permeability. Here, we investigated the anti-colitic effects and mechanism of L. plantarum CBT LP3 (LP...
Cefoperazone induces esterase B expression by EstR and esterase B enhances cefoperazone activity at the periplasm [0.03%]
酯酶B通过EstR诱导表达并可在周质中增强头孢泊肟活性
Neal Toewiwat,Wirongrong Whangsuk,Poonsakdi Ploypradith et al.
Neal Toewiwat et al.
The occurrence of antibiotic resistance bacteria has become a major threat to public health. We have recently discovered a transcriptional activator that belongs to MarR family, EstR, and an esterase B (EstB) with a newly proposed de-arenet...
A novel type I toxin-antitoxin system modulates persister cell formation in Staphylococcus aureus [0.03%]
Staphylococcus aureus中的一种新型I型毒抗系统调节耐受细胞的形成
Gul Habib,Jiade Zhu,Baolin Sun
Gul Habib
A plethora of toxin-antitoxin systems exist in bacteria and has multilateral roles in bacterial pathogenesis and virulence. Toxin-antitoxin systems have been involved in persister cell formation in Escherichia coli and Mycobacterium but hav...
The EngCP endo α-N-acetylgalactosaminidase is a virulence factor involved in Clostridium perfringens gas gangrene infections [0.03%]
恩革CP内切α-岩藻糖苷酶是产气荚膜梭菌感染中的一种毒力因子
Jackie K Cheung,Vicki Adams,Danielle D&#x;Souza et al.
Jackie K Cheung et al.
Clostridium perfringens is the causative agent of human clostridial myonecrosis; the major toxins involved in this disease are α-toxin and perfringolysin O. The RevSR two-component regulatory system has been shown to be involved in regulat...
How bacterial pathogens of the gastrointestinal tract use the mucosal glyco-code to harness mucus and microbiota: New ways to study an ancient bag of tricks [0.03%]
肠道致病菌如何利用粘膜糖基密码来捕获粘液和微生物群：探索一个古老伎俩的新方法
Christine Josenhans,Johannes Müthing,Lothar Elling et al.
Christine Josenhans et al.
During the last decades, the flourishing scientific field of molecular pathogenesis brought groundbreaking knowledge of the mechanisms of pathogenicity and the underlying bacterial virulence factors to cause infectious diseases. However, a ...
Resistance Sniffer: An online tool for prediction of drug resistance patterns of Mycobacterium tuberculosis isolates using next generation sequencing data [0.03%]
基于下一代测序数据的抗药性预测工具抵抗嗅探器：预测分离结核杆菌耐药模式的在线工具
Dillon Muzondiwa,Awelani Mutshembele,Rian E Pierneef et al.
Dillon Muzondiwa et al.
The effective control of multidrug resistant tuberculosis (MDR-TB) relies upon the timely diagnosis and correct treatment of all tuberculosis cases. Whole genome sequencing (WGS) has great potential as a method for the rapid diagnosis of dr...
Susceptibility of aging mice to listeriosis: Role of anti-inflammatory responses with enhanced Treg-cell expression of CD39/CD73 and Th-17 cells [0.03%]
衰老小鼠利斯特菌病的易感性：抗炎反应的作用及Treg细胞表达CD39/CD73和Th-17细胞的功能增强
M Samiul Alam,Christopher Cavanaugh,Marion Pereira et al.
M Samiul Alam et al.
Foodborne Listeria monocytogenes (Lm) causes serious illness and death in immunosuppressed hosts, including the elderly population. We investigated Lm susceptibility and inflammatory cytokines in geriatric mice. Young-adult and old mice wer...
Prevalence of hypermutator isolates of Achromobacter spp. from cystic fibrosis patients [0.03%]
囊性纤维化患者来源的高突变率Achromobacter菌株的流行情况
Winnie Ridderberg,Kurt Jensen Handberg,Niels Nørskov-Lauritsen
Winnie Ridderberg
Bacteria colonising the lungs of cystic fibrosis (CF) patients encounter high selective pressures. Hypermutation facilitates adaptation to fluctuating environments, and hypermutator strains are frequently isolated from CF patients. We inves...
Discovery of Paenibacillus larvae ERIC V: Phenotypic and genomic comparison to genotypes ERIC I-IV reveal different inventories of virulence factors which correlate with epidemiological prevalences of American Foulbrood [0.03%]
棒状杆菌病原体帕氏芽孢杆菌ERIC V型的发现：ERIC I-IV基因型表型及基因组比较显示其致病因子构成不同且与美洲幼虫腐臭病的流行相关性各异
Hannes Beims,Boyke Bunk,Silvio Erler et al.
Hannes Beims et al.
Paenibacillus larvae is the etiological agent of American Foulbrood (AFB), a highly contagious brood disease of honey bees (Apis mellifera). AFB requires mandatory reporting to the veterinary authority in many countries and until now four g...
Characterization of blaCTX-M-14 transposition from plasmid to chromosome in Escherichia coli experimental strain [0.03%]
肠杆菌科细菌人工整合子介导的CTX-M-14基因从质粒向染色体转移的研究
Kouta Hamamoto,Toshiro Tokunaga,Nobuyoshi Yagi et al.
Kouta Hamamoto et al.
Mostly, blaCTX-M is found on transferable plasmids as a component of the blaCTX-M transposition unit containing an insertion sequence, ISEcp1, which exists on the upstream region of blaCTX-Ms. Several recent studies conducted in clinical an...