Novel role of the phosphatidylinositol phosphatase Sac1 in membrane homeostasis and polarized growth in Candida albicans [0.03%]
新型磷脂酶Sac1在膜稳态和白念珠菌极性生长中的作用
Bing Zhang,Liping Peng,Nali Zhu et al.
Bing Zhang et al.
Phosphoinositides (PIPs) are one kind of membrane components functioning in many intracellular processes, especially in signaling transduction and membrane transport. Phosphatidylinositide phosphatases (PIPases) are specifically important f...
Effect of progesterone on Candida albicans biofilm formation under acidic conditions: A transcriptomic analysis [0.03%]
孕酮在酸性条件下对白色念珠菌生物被膜形成的影响：转录组学分析
Bruna Gonçalves,Ruben Bernardo,Can Wang et al.
Bruna Gonçalves et al.
Vulvovaginal candidiasis (VVC) caused by Candida albicans is a common disease worldwide. A very important C. albicans virulence factor is its ability to form biofilms on epithelium and/or on intrauterine devices promoting VVC. It has been s...
The Treponema pallidum outer membrane protein Tp92 activates endothelial cells via the chemerin/CMKLR1 pathway [0.03%]
Tp92蛋白通过 chemerin/CMKLR1途径活化梅毒苍白螺旋体感染的内皮细胞
Rui-Li Zhang,Qian-Qiu Wang
Rui-Li Zhang
Endothelium damage caused by Treponema pallidum is the key step in the systemic dissemination and pathophysiology of syphilis, particularly cardiovascular syphilis and neurosyphilis. However, the molecular mechanisms supporting endothelium ...
Recombinant N-terminal outer membrane porin (OprF) of Pseudomonas aeruginosa is a promising vaccine candidate against both P. aeruginosa and some strains of Acinetobacter baumannii [0.03%]
铜绿假单胞菌重组N端外膜孔蛋白（OprF）是铜绿假单胞菌和某些鲍曼不动杆菌株疫苗的候选药物
Mohammed Bahey-El-Din,Shaymaa Abdelrahman Mohamed,Salah Ahmed Sheweita et al.
Mohammed Bahey-El-Din et al.
Pseudomonas aeruginosa is an evolving pathogen which can cause serious infections especially to immunocompromised patients. Its high resistance profile to antibiotics results in difficulty, and sometimes impossibility, in treating afflicted...
Development of a novel MALDI-TOF MS-based bile solubility test for rapid discrimination of Streptococcus pneumoniae [0.03%]
一种新型的基于MALDI-TOF MS的胆汁溶解试验的建立及快速鉴别肺炎链球菌的能力评估
Evgeny A Idelevich,Andreas Schlattmann,Markus Kostrzewa et al.
Evgeny A Idelevich et al.
Differentiation of Streptococcus pneumoniae from other Streptococcus mitis group streptococci (SMGS) remains challenging despite the introduction of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS)...
Complete genome sequence and genome-scale metabolic modelling of Acinetobacter baumannii type strain ATCC 19606 [0.03%]
阿克莱尼伯克霍尔德菌标准菌株ATCC 19606的全基因组序列和基因组范围代谢模型的完成
Yan Zhu,Jing Lu,Jinxin Zhao et al.
Yan Zhu et al.
Multidrug-resistant (MDR) Acinetobacter baumannii is a critical threat to global health. The type strain ATCC 19606 has been widely used in studying the virulence, pathogenesis and mechanisms of antimicrobial resistance in A. baumannii. How...
Analysis of the dynamics of Staphylococcus aureus binding to white blood cells using whole blood assay and geno-to-pheno mapping [0.03%]
利用全血测定和基因型-表型图谱分析金黄色葡萄球菌与白细胞结合的动力学
Daria Gaidar,Alice Jonas,Ruslan Akulenko et al.
Daria Gaidar et al.
Given that binding and internalization of bacteria to host cells promotes infections and invasion, we aimed at characterizing how various S. aureus isolates adhere to and are internalized by different white blood cells. In particular, the r...
Naringin sensitizes the antibiofilm effect of ciprofloxacin and tetracycline against Pseudomonas aeruginosa biofilm [0.03%]
芸香苷增敏环丙沙星和四环素抑制绿脓杆菌生物被膜的作用
Pia Dey,Debaprasad Parai,Malabika Banerjee et al.
Pia Dey et al.
The study aims to explore the combinatorial effect of naringin with antibiotics, ciprofloxacin and tetracycline on Pseudomonas aeruginosa biofilms. The antibiofilm efficacy of selected treatment regimes against P. aeruginosa biofilm were qu...
A snapshot of diversity: Intraclonal variation of Escherichia coli clones as commensals and pathogens [0.03%]
埃希氏大肠杆菌克隆体作为共生菌和致病菌的体内克隆变异性的研究进展
Marc Stegger,Rikke Fleron Leihof,Sharmin Baig et al.
Marc Stegger et al.
Whole-genome sequencing has enabled detailed studies on bacterial evolution during infection, but there is limited knowledge on intraclonal variation. In this study, we sought to provide a snapshot of the intraclonal diversity of Escherichi...
ClpB is an essential stress regulator of Mycobacterium tuberculosis and endows survival advantage to dormant bacilli [0.03%]
克拉布蛋白是结核分枝杆菌的重要应激调节蛋白并能赋予休眠菌株生存优势
Prajna Tripathi,Lalit K Singh,Sujata Kumari et al.
Prajna Tripathi et al.
The ability to tolerate multiple host derived stresses, resist eradication and persist within the infected individuals is central to the pathogenicity of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB). Mycobacter...