Immunostimulatory efficacy and protective potential of putative TgERK7 protein in mice experimentally infected by Toxoplasma gondii [0.03%]
TgERK7蛋白的免疫刺激效应及其对小鼠弓形虫感染的保护作用研究
Zhong-Yuan Li,Hai-Ting Guo,Guillermo Calderón-Mantilla et al.
Zhong-Yuan Li et al.
The extracellular signal-regulated kinases (ERKs) serve as important determinants of cellular signal transduction pathways, and hence may play important roles during infections. Previous work suggested that putative ERK7 of Toxoplasma gondi...
Exploring the antibacterial mechanism of essential oils by membrane permeability, apoptosis and biofilm formation combination with proteomics analysis against methicillin-resistant staphylococcus aureus [0.03%]
通过膜通透性、凋亡和生物被膜形成联合蛋白质组学分析探讨抗菌精油的抗甲氧西林金黄色葡萄球菌的作用机制研究
Cailin Tang,Jiali Chen,Lixia Zhang et al.
Cailin Tang et al.
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the important causes of food poisoning and infectious diseases worldwide, it can produce a large number of virulence factors, enhance the colonization ability of the host so that ...
After Pettenkofer. Munich's Institute of Hygiene and the long shadow of National Socialism, 1894-1974 [0.03%]
在彭滕科费尔之后：慕尼黑卫生学研究所与纳粹主义的长期影响，1894—1974年
Mathias Schütz
Mathias Schütz
The year 2019 marked the 140th anniversary of the inauguration of the first Institute of Hygiene, which was established for Max von Pettenkofer at the university of Munich. After Pettenkofer, his successors tried to advance the science of h...
Transcriptional regulation of virulence factors Hla and phenol-soluble modulins α by AraC-type regulator Rbf in Staphylococcus aureus [0.03%]
AraC型调节因子Rbf调控金黄色葡萄球菌毒力因子Hla和可溶性模体α的转录
Bo Fang,Banghui Liu,Baolin Sun
Bo Fang
Staphylococcus aureus is a gram-positive pathogenic bacterium and is capable of secreting numerous toxins interfering directly with the host to cause acute infections. Rbf, a transcriptional regulator of AraC/XylS family, has been reported ...
Synthesis and anti-pseudomonal activity of new ß-Ala modified analogues of the antimicrobial peptide anoplin [0.03%]
新环状阳离子抗菌肽anoplin的乙醇胺衍生物的合成及其抗假单胞菌活性研究
Chao Zhong,Yuewen Zhu,Ningyi Zhu et al.
Chao Zhong et al.
Due to the rise of antibiotic-resistant bacteria around the world, AMPs (antimicrobial peptides), depending on non-specific membrane mechanism and low tendency to develop bacterial resistance, attract widespread attentions as novel antimicr...
Molecular characterization of a carbon dioxide-dependent Escherichia coli small-colony variant isolated from blood cultures [0.03%]
血培养分离的二氧化碳依赖型大肠埃希氏菌小菌落变异株的分子表征
Takehisa Matsumoto,Masayuki Hashimoto,Ching-Hao Teng et al.
Takehisa Matsumoto et al.
A carbon dioxide-dependent small-colony variant of Escherichia coli SH4888 was isolated from blood cultures of a patient with cholangitis. To date, little is known regarding the molecular mechanisms leading to formation of carbon dioxide-de...
Live attenuated Salmonella Typhimurium with monophosphoryl lipid A retains ability to induce T-cell and humoral immune responses against heterologous polysaccharide of Shigella flexneri 2a [0.03%]
单磷酸脂A活化的大肠杆菌泰密菌诱导沙门氏菌痢疾活异源多糖T细胞及体液免疫应答
Qing Liu,Huali Su,Xiaoping Bian et al.
Qing Liu et al.
Shigella flexneri 2a (Sf2a) is one of the most frequently isolated Shigella strains that causes the endemic shigellosis in developing countries. In this study, we used recombinant attenuated Salmonella vaccine (RASV) strains to deliver Sf2a...
Myo-Inositol as a carbon substrate in Francisella and insights into the metabolism of Francisella sp. strain W12-1067 [0.03%]
肌醇作为弗朗西斯菌的碳源及W12-1067菌株的代谢分析
Fan Chen,Kristin Köppen,Kerstin Rydzewski et al.
Fan Chen et al.
Recently, a new environmental Francisella strain, Francisella sp. strain W12-1067, has been identified in Germany. This strain is negative for the Francisella pathogenicity island (FPI) but exhibits a putative alternative type VI secretion ...
Microbiota and cancer: host cellular mechanisms activated by gut microbial metabolites [0.03%]
微生物组与癌症：肠道菌群代谢产物激活的宿主细胞机制
Sofia A Tsvetikova,Elena I Koshel
Sofia A Tsvetikova
In recent years, more and more data indicate the effect of human microbiota on carcinogenesis. Despite the numerous studies on the relationship between gut microbiota and carcinogenesis, the exact mechanisms of this interaction are not well...
Raquel Hurtado,Lenin Maturrano,Vasco Azevedo et al.
Raquel Hurtado et al.
Pasteurella multocida is an important veterinary pathogen able to infect a wide range of animals in a broad spectrum of diseases. P. multocida is a complex microorganism in relation to its genomic flexibility, host adaptation and pathogenes...