MicroRNA-31 mediated by interferon regulatory factor 7 signaling facilitates control of Mycobacterium tuberculosis infection [0.03%]
干扰素调节因子7信号介导的微小核糖核酸-31促进抗结核感染免疫反应
Zhiyi Zhang,Qiongdan Mai,Lijia Yang et al.
Zhiyi Zhang et al.
Tuberculosis (TB) induced by Mycobacterium tuberculosis (M. tuberculosis) infection remains a global most deadly infectious disease. While development of more effective TB vaccines and therapeutics relies on identifications of true biomarke...
Mechanisms of promoting the differentiation and bone resorption function of osteoclasts by Staphylococcus aureus infection [0.03%]
金黄色葡萄球菌感染促进破骨细胞分化及骨吸收功能的机制研究
Zelei Tong,Zhihao Chen,Ziyuan Li et al.
Zelei Tong et al.
Bone infection is a common and serious complication in the field of orthopedics, which frequently leads to excessive bone destruction and fracture nonunion. Staphylococcus aureus (S. aureus) infection affects bone cell function which, in tu...
Machine learning on the road to unlocking microbiota's potential for boosting immune checkpoint therapy [0.03%]
机器学习解锁微生物组潜力以增强免疫检查点疗法的道路上
Szymon Wojciechowski,Monika Majchrzak-Górecka,Paweł Biernat et al.
Szymon Wojciechowski et al.
The intestinal microbiota is a complex and diverse ecological community that fulfills multiple functions and substantially impacts human health. Despite its plasticity, unfavorable conditions can cause perturbations leading to so-called dys...
Klebsiella pneumoniae activates the TGF-β signaling pathway to adhere to and invade intestinal epithelial cells via enhancing TLL1 expression [0.03%]
Klebsiella pneumoniae通过增强TLL1表达黏附并侵入肠上皮细胞的机制研究
Jun Liu,Shiliang Zhang,Hao Pei et al.
Jun Liu et al.
Klebsiella pneumoniae is a gram-negative bacterium that can cause many diseases in hospitals and communities. Intestinal K. pneumoniae infections are relatively rare. Most K. pneumoniae infections begin with the colonization of the gastroin...
Comprehensive investigation of antibiotic resistance gene content in cfiA-harboring Bacteroides fragilis isolates of human and animal origins by whole genome sequencing [0.03%]
全基因组测序揭示分离自人和动物源脆弱拟杆菌的cfiA携带质粒的抗生素抗性基因概况
Huiluo Cao,Melissa Chun-Jiao Liu,Man-Ki Tong et al.
Huiluo Cao et al.
Introduction: The emergence of multidrug resistance in Bacteroides fragilis, especially the phylogenetic lineage carrying the carbapenemase gene cfiA, represents an increasing threat to human health. However, knowledge on...
Jennifer Schauer,Sören G Gatermann,Jessica Eisfeld et al.
Jennifer Schauer et al.
Objectives: To report the detection of the class D carbapenemase OXA-181 in an MDR clinical Pseudomonas aeruginosa isolate in Germany. Methods: ...
Can Mycobacterium tuberculosis infection lead to cancer? Call for a paradigm shift in understanding TB and cancer [0.03%]
结核分枝杆菌感染可以导致癌症吗？重新认识结核病和癌症的关系
Asrar A Malik,Javaid A Sheikh,Nasreen Z Ehtesham et al.
Asrar A Malik et al.
Infections are known to cause tumours though more attributed to viruses. Strong epidemiological links suggest association between bacterial infections and cancers as exemplified by Helicobacter pylori and Salmonella spp. Infection with Myco...
Regulatory interplay of RpoS and RssB controls motility and colonization in Vibrio cholerae [0.03%]
RpoS和RssB的调控互作控制霍乱弧菌的运动性和定植能力
Martina Wölflingseder,Sarah Tutz,Vera H Fengler et al.
Martina Wölflingseder et al.
Cholera is a life-threatening diarrheal disease caused by the human pathogenic bacterium Vibrio cholerae. Regulatory elements are essential for bacterial transition between the natural aquatic environment and the human host. One of them is ...
Treponema pallidum Tp0751 alters the expression of tight junction proteins by promoting bEnd3 cell apoptosis and IL-6 secretion [0.03%]
Tp0751通过促进bEnd3细胞凋亡和IL-6释放来改变紧密连接蛋白的表达
Simin Lu,Jianye Wang,Zhangping He et al.
Simin Lu et al.
Background: Neurosyphilis is a serious complication caused by the invasion of the central nervous system by Treponema pallidum subsp. pallidum (T. pallidum). However, the molecular mechanism by which T. pallidum crosses t...
Global epidemiology of antimicrobial resistance in commensal Neisseria species: A systematic review [0.03%]
共生奈瑟菌物种的全球抗菌药物耐药性流行病学：一项系统评价
Thibaut Vanbaelen,Christophe Van Dijck,Jolein Laumen et al.
Thibaut Vanbaelen et al.
Background: Commensal Neisseria species (spp). represent an important reservoir of antimicrobial resistance genes for pathogenic Neisseria spp. In this systematic review, we aimed to assess the antimicrobial susceptibilit...