The alternative sigma factor B modulates virulence gene expression in a murine Staphylococcus aureus infection model but does not influence kidney gene expression pattern of the host [0.03%]
一种替代的σ因子B在小鼠金黄色葡萄球菌感染模型中调节毒力基因表达，但不影响宿主肾脏基因表达模式
Maren Depke,Marc Burian,Tina Schäfer et al.
Maren Depke et al.
Infections caused by Staphylococcus aureus are associated with significant morbidity and mortality and are an increasing threat not only in hospital settings. The expression of the staphylococcal virulence factor repertoire is known to be a...
Oral and faecal lactobacilli and their expression of mannose-specific adhesins in individuals with and without IgA deficiency [0.03%]
IgA缺乏症患者及其唾液和粪便乳酸菌中曼能糖特异黏附素的表达
Elisabet Lönnermark,Forough Nowrouzinan,Ingegerd Adlerberth et al.
Elisabet Lönnermark et al.
Lactobacilli are present in the intestine and oral cavity of most adults. Secretory IgA in mucosal secretions may provide carbohydrate receptors for bacterial adhesins. Here, oral and faecal samples from 33 IgA-deficient individuals and 34 ...
Haemophilus influenzae in children with cystic fibrosis: antimicrobial susceptibility, molecular epidemiology, distribution of adhesins and biofilm formation [0.03%]
儿童肺炎链球菌的药物敏感性、分子病原学、粘附素分布及生物膜形成能力的研究——囊性纤维化患者的病例报告
Rita Cardines,Maria Giufrè,Arianna Pompilio et al.
Rita Cardines et al.
Haemophilus influenzae commonly infects the respiratory tract of patients with cystic fibrosis (CF), early in childhood. In this investigation, 79 H. influenzae isolates were recovered from the respiratory secretions of 64 CF patients (medi...
The CEM-NET initiative: molecular biology and epidemiology in alliance--tracking antibiotic-resistant staphylococci and pneumococci in hospitals and in the community [0.03%]
CEM-NET行动计划：分子生物学与流行病学的联合行动——在医院和社区追踪耐抗生素金黄色葡萄球菌和肺炎链球菌
Herminia de Lencastre,Alexander Tomasz
Herminia de Lencastre
In this brief report, we provide a portrait of the CEM-NET initiative and review studies that highlight contributions of this molecular epidemiological network to the understanding of the molecular mechanisms of drug resistance in Staphyloc...
First multi-epitope subunit vaccine against extraintestinal pathogenic Escherichia coli delivered by a bacterial type-3 secretion system (T3SS) [0.03%]
通过细菌第三类分泌系统输送的针对肠外致病性大肠杆菌的首个多抗原表位亚单位疫苗
Andreas Wieser,Giuseppe Magistro,Dominik Nörenberg et al.
Andreas Wieser et al.
Infections due to extraintestinal pathogenic E. coli (ExPEC) are very common in humans as well as in animals. In humans ExPEC infections include urinary tract infections (UTI), septicemia, and wound infections, which result in significant m...
DNA sequence analysis of the composite plasmid pTC conferring virulence and antimicrobial resistance for porcine enterotoxigenic Escherichia coli [0.03%]
致病性和抗微生物性复合质粒pTC的基因序列分析以预防猪肠毒性大肠杆菌感染
Péter Z Fekete,Elzbieta Brzuszkiewicz,Gabriele Blum-Oehler et al.
Péter Z Fekete et al.
In this study the plasmid pTC, a 90 kb self-conjugative virulence plasmid of the porcine enterotoxigenic Escherichia coli (ETEC) strain EC2173 encoding the STa and STb heat-stable enterotoxins and tetracycline resistance, has been sequenced...
Population genetics and evolution of the pan-genome of Streptococcus pneumoniae [0.03%]
肺炎链球菌泛基因组的群体遗传及进化研究
Alessandro Muzzi,Claudio Donati
Alessandro Muzzi
The genetic variability in bacterial species is much larger than in other kingdoms of life. The gene content between pairs of isolates can diverge by as much as 30% in species like Escherichia coli or Streptococcus pneumoniae. This unexpect...
Methicillin-resistant staphylococci (MRS) and extended-spectrum beta-lactamases (ESBL)-producing Enterobacteriaceae in companion animals: nosocomial infections as one reason for the rising prevalence of these potential zoonotic pathogens in clinical samples [0.03%]
青霉素耐药金黄色葡萄球菌和产超广谱β-内酰胺酶肠杆菌科细菌在伴侣动物中的医院感染及这些具有潜在人畜共患特性的病原体的临床标本中越来越常见的原因分析研究
Lothar H Wieler,Christa Ewers,Sebastian Guenther et al.
Lothar H Wieler et al.
The ongoing change in the relationship between humans and companion animals is hallmarked by the increasing intensive care provided to companion animals in veterinary medicine, resulting in growing numbers of high-risk animal patients. The ...
Climate change and infectious diseases--impact of global warming and climate change on infectious diseases: myth or reality? [0.03%]
气候变化与传染病——全球变暖和气候变化对传染病的影响：神话还是现实？
Seyed E Hasnain,Bärbel Friedrich,Thomas Mettenleiter et al.
Seyed E Hasnain et al.
Alessandra Carattoli
Alessandra Carattoli
A plasmid is defined as a double stranded, circular DNA molecule capable of autonomous replication. By definition, plasmids do not carry genes essential for the growth of host cells under non-stressed conditions but they have systems which ...