Past and present seroprevalence and disease burden estimates of Toxoplasma gondii infections in Germany: An appreciation of the role of serodiagnostics [0.03%]
德国弓形虫病的流行现状及疾病负担估计：血清诊断的作用
Frank Seeber
Frank Seeber
Toxoplasmosis is one of the major foodborne parasitic diseases in Germany, with 49% of its population chronically infected with its causative agent, Toxoplasma gondii. Although the acute disease is usually benign in immunocompetent individu...
Interdisciplinary studies on Coxiella burnetii: From molecular to cellular, to host, to one health research [0.03%]
烧伤热螺旋体的交叉学科研究：从分子到细胞，再到宿主，最后到健康问题研究
Benjamin U Bauer,Michael R Knittler,Jennifer Andrack et al.
Benjamin U Bauer et al.
The Q-GAPS (Q fever GermAn interdisciplinary Program for reSearch) consortium was launched in 2017 as a German consortium of more than 20 scientists with exceptional expertise, competence, and substantial knowledge in the field of the Q fev...
ListiWiki: A database for the foodborne pathogen Listeria monocytogenes [0.03%]
_LISTIWIKI：用于致病菌单核细胞增生性李斯特氏杆菌的数据库_
Christoph Elfmann,Bingyao Zhu,Jörg Stülke et al.
Christoph Elfmann et al.
Listeria monocytogenes is a Gram positive foodborne pathogen that regularly causes outbreaks of systemic infectious diseases. The bacterium maintains a facultative intracellular lifestyle; it thrives under a variety of environmental conditi...
Effects of resveratrol on macrophages after phagocytosis of Candida glabrata [0.03%]
白藜醇对卡帕斯氏毕萨酵母菌胞吞后的巨噬细胞的影响
Zong-Han Chen,Meng Guan,Wei-Jia Zhao
Zong-Han Chen
Candida glabrata is believed to be the underlying cause of many human ailments, including oral, gastrointestinal, and vaginal disorders. C. glabrata-caused deep-seated infections, coupled with its resistance to antifungal drugs, may contrib...
Multicenter evaluation of BioFire JI panel related to improved microbiological diagnostics on acute osteoarticular infections [0.03%]
多中心评估BioFire JI Panel对急性骨关节感染微生物学诊断的改善作用
Llanos Salar-Vidal,Catarina Chaves,Ileana T Dianzo-Delgado et al.
Llanos Salar-Vidal et al.
Microbiological diagnosis of osteoarticular infections (OI) is crucial for a successful treatment. A prospective multicenter study including 262 synovial fluids with suspicion of acute OI was performed between July 2021 and October of 2022....
Polydatin alleviates mycoplasma pneumoniae-induced injury via inhibition of Caspase-1/GSDMD-dependent pyroptosis [0.03%]
聚茋酸钾通过抑制半胱天冬酶-1/GSDMD依赖性焦亡改善肺炎支原体诱导的损伤作用
Yiliu Chen,Yonghong Jiang,Xiuxiu Liu et al.
Yiliu Chen et al.
Mycoplasma pneumoniae (MP) is one of the main pathogens causing community acquired pneumonia (CAP) in children and adults. Previous pharmacological and clinical studies have shown that Polydatin (PD) exerts anti-inflammatory action by confe...
Innate activation of human neutrophils and neutrophil-like cells by the pro-inflammatory bacterial metabolite ADP-heptose and Helicobacter pylori [0.03%]
二磷酸七糖和幽门螺旋杆菌通过内源途径活化中性粒细胞及中性粒细胞样细胞
Larissa Faass,Martina Hauke,Saskia C Stein et al.
Larissa Faass et al.
Lipopolysaccharide inner core heptose metabolites, including ADP-heptose, play a substantial role in the activation of cell-autonomous innate immune responses in eukaryotic cells, via the ALPK1-TIFA signaling pathway, as demonstrated for va...
Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades [0.03%]
弗朗西斯菌虎克亚种谱系的表型和基因型鉴别
Kristin Köppen,Kerstin Rydzewski,Joerg Doellinger et al.
Kristin Köppen et al.
Francisella tularensis is the causative agent of tularemia, a zoonotic disease with a wide host range. F. tularensis ssp. holarctica (Fth) is of clinical relevance for European countries, including Germany. Whole genome sequencing methods, ...
Heat shock protein 70 is involved in polaprezinc driven cell protection against Helicobacter pylori-induced injury [0.03%]
热休克蛋白70参与了Polaprezinc介导的细胞保护作用以对抗幽门螺旋杆菌引起的损伤
Fansen Meng,Siying Zhu,Meiliang Gong et al.
Fansen Meng et al.
Polaprezinc (PZ) plays a role in the protection of gastric mucosa and inhibiting Helicobacter pylori (H. pylori) growth in vitro. The objective of this study was to determine the protective effects of PZ on human gastric epithelial cells (G...
Preclinical evaluation of 2-[18F]fluorodeoxysorbitol as a tracer for targeted imaging of Enterobacterales infection [0.03%]
2-[-18F]氟脱氧山梨醇作为靶向成像肠杆菌目感染示踪剂的临床前评估研究
Lisanne M Braams,Jürgen W A Sijbesma,Hendrikus H Boersma et al.
Lisanne M Braams et al.
Fluorine-18-fluorodeoxyglucose ([18F]FDG) positron emission tomography (18F-FDG-PET) is widely used for the detection of inflammatory and infectious diseases. Although this modality has proven to be a useful diagnostic tool, reliable distin...