Genetic modules for α-factor pheromone controlled growth regulation of Saccharomyces cerevisiae [0.03%]
酿酒酵母α-因子激素控制生长的遗传模块
Uta Gutbier,Juliane Korp,Lennart Scheufler et al.
Uta Gutbier et al.
Saccharomyces cerevisiae is a commonly used microorganism in the biotechnological industry. For the industrial heterologous production of compounds, it is of great advantage to work with growth-controllable yeast strains. In our work, we ut...
A perspective-driven and technical evaluation of machine learning in bioreactor scale-up: A case-study for potential model developments [0.03%]
从视角和技术角度评估生物反应器放大的机器学习：潜在模型发展的案例研究
Masih Karimi Alavijeh,Yih Yean Lee,Sally L Gras
Masih Karimi Alavijeh
Bioreactor scale-up and scale-down have always been a topical issue for the biopharmaceutical industry and despite considerable effort, the identification of a fail-safe strategy for bioprocess development across scales remains a challenge....
Gas supply apparatus using rotational motion of shaking incubator for flask culture of aerobic microorganisms [0.03%]
一种利用摇瓶培养好氧微生物的振荡培养箱旋转运动供气的装置
Minseo Jung,Jinwon Lee,Si Jae Park et al.
Minseo Jung et al.
Shake flask cultivation, a cornerstone in bioprocess research encounters limitations in supplying sufficient oxygen and exchanging gases, restricting its accuracy in assessing microbial growth and metabolic activity. In this communication, ...
Robot-based 6D bioprinting for soft tissue biomedical applications [0.03%]
基于机器人的六维生物打印在软组织生物医学应用中的研究
Franziska B Albrecht,Freia F Schmidt,Christian Schmidt et al.
Franziska B Albrecht et al.
Within this interdisciplinary study, we demonstrate the applicability of a 6D printer for soft tissue engineering models. For this purpose, a special plant was constructed, combining the technical requirements for 6D printing with the biolo...
Evaluation of prokaryotic and eukaryotic microbial communities on microplastic-associated biofilms in marine and freshwater environments [0.03%]
评估海洋和淡水中微塑料相关生物膜上原核和真核微生物群落的状况
Şuheda Reisoglu,Ceren Cati,Meral Yurtsever et al.
Şuheda Reisoglu et al.
Microplastics (MPs) are major concern due to their potential harm to ecosystems and most research has focused on their presence and fate, with limited attention to their biodegradation in aquatic ecosystems. Nevertheless, MPs act as hotspot...
Current trends in medium-chain-length polyhydroxyalkanoates: Microbial production, purification, and characterization [0.03%]
中链长度聚羟基烷酸酯的当前趋势：微生物生产、纯化和表征
Thomas Hahn,Melissa Ortega Alzate,Steven Leonhardt et al.
Thomas Hahn et al.
Polyhydroxyalkanoates (PHAs) have gained interest recently due to their biodegradability and versatility. In particular, the chemical compositions of medium-chain-length (mcl)-PHAs are highly diverse, comprising different monomers containin...
Stable overexpression of native and artificial miRNAs for the production of differentially fucosylated antibodies in CHO cells [0.03%]
稳定过表达天然及人工microRNA以在CHO细胞中生产不同岩藻糖基化抗体
Patrick Schlossbauer,Lukas Naumann,Florian Klingler et al.
Patrick Schlossbauer et al.
Cell engineering strategies typically rely on energy-consuming overexpression of genes or radical gene-knock out. Both strategies are not particularly convenient for the generation of slightly modulated phenotypes, as needed in biosimilar d...
Miao Zhou,Jie Ma,Meng Kang et al.
Miao Zhou et al.
Flavonoids are widely distributed in nature and have a variety of beneficial biological effects, including antioxidant, anti-inflammatory, and anti-obesity effects. All of these are related to gut microbiota, and flavonoids also serve as a ...
Regulation on C2-C8 carboxylic acid biosynthesis from anaerobic CO2 fermentation [0.03%]
厌氧二氧化碳发酵合成C2-C8羧酸的调控机制研究进展
Wanling Wu,Zhiqi Li,Guangqing Liu et al.
Wanling Wu et al.
Bioconversion of CO2 into liquid fuels or chemicals, preferred medium chain carboxylic acids (caproic and caprylic acid), is an attractive CO2 utilization technology. The present study aims to investigate the effects of different ratios of ...
Feng Ju,Qixiao Zhai,Gang Luo et al.
Feng Ju et al.