Rational Design of Amphiphilic Copillar[5]arene Conjugates for Enhanced Nanodelivery: Synthesis, Nanoparticle Optimization, and In Vitro Biocompatibility [0.03%]
用于增强纳米递送的两亲性共-pill[5]芳烃缀合物的理性设计：合成，纳米粒子优化和体外生物相容性研究
Krishna Kanta Choudhury,Russel Aliamintakath Sharafudheen,Kajol et al.
Krishna Kanta Choudhury et al.
A single component, synthetically tunable amphiphilic copillar[5]arene platform was developed as a modular supramolecular scaffold for therapeutic nano-delivery. Structural variation of the hydrophobic segment, together with PEG functionali...
A Pure Zwitterionic PSBMA Coating With Ultra-Low Friction, Anti-Adhesion and High Stability for Blood-Contacting Catheters [0.03%]
一种用于血液接触导管的超低摩擦、防粘附和高稳定的纯两性离子PSBMA涂层
Jiale Cao,Xinzhong Song,Xiangkuan Zhang et al.
Jiale Cao et al.
With the increasing demand for blood-contacting medical devices, surface-related limitations of conventional materials, including high friction, nonspecific adhesion, and insufficient long-term stability, have become critical challenges for...
Alginate and Chitosan-Based Hydrogels: Effects on the Stability of Encapsulated Quercetin Under Multiple Stress Conditions [0.03%]
海藻酸盐和壳聚糖基水凝胶对包裹芦丁在多种胁迫条件下的稳定性的影响
Marta Tsirigotis-Maniecka,Maria Zoumpanioti,Izabela Pawlaczyk-Graja
Marta Tsirigotis-Maniecka
In this study, hydrogel systems were investigated as protective carriers for quercetin (Que), a sensitive phytopharmaceutical. Matrix-type calcium alginate microparticles and capsule-type calcium alginate-chitosan microparticles were subjec...
Impact of a Reinforced Graphene Oxide and Alginate Hydrogel with an Oxygen Releasing System on the Biocompatibility of Pancreatic β-Cells for Diabetes Therapy [0.03%]
一种含强化氧化石墨烯和海藻酸钠水凝胶及其供氧体系对糖尿病治疗中胰岛β细胞生物相容性的影响
Elías Cuartas-Gómez,Oscar Vargas-Ceballos,Natalia Moreno-Castellanos
Elías Cuartas-Gómez
Type 1 diabetes is characterized by autoimmune destruction of pancreatic β-cells, resulting in insulin deficiency and impaired blood glucose regulation. Cell encapsulation using alginate-based hydrogels offers immunoprotection but faces ch...
A Thermosensitive Hydroxybutyl Chitosan/Microalgae Hydrogel With Antibacterial and Antioxidant Activities for Accelerating Burn Wound Healing [0.03%]
一种具有抗菌和抗氧化活性的热敏型羟丁基壳聚糖/微藻水凝胶用于促进烧伤创面修复
Yuan Feng,Ding Lin,Zhenhao Li et al.
Yuan Feng et al.
Capitalizing on microalgae extract (MAE) to scavenge reactive oxygen species, repair cell damage, and modulate macrophage related inflammatory responses, an injectable thermosensitive responsive hydrogel (HBC-MAE) was developed to promote b...
Thiol-Based Neuroprotective Copolymers Acutely Restore Redox Metabolism and Mediate Vasogenic Edema in a Mouse Model of Traumatic Brain Injury [0.03%]
一类基于硫醇的神经保护共聚物通过恢复脑创伤小鼠急性期氧化还原代谢并调节血管源性水肿发挥作用
Evan T Curtis,Brandon Z McDonald,Aria W Tarudji et al.
Evan T Curtis et al.
Effective pharmaceutical interventions for treating the secondary damage associated with traumatic brain injury (TBI) are limited due to poor delivery into the brain, insufficient target engagement, and an incomplete understanding of the pa...
Structural Characterization and Wound Healing Activity of Sulfated Glycosaminoglycans from Acipenser Baerii Cartilage: Potential Regulation of Fibroblast Function [0.03%]
体外结构表征及生物学活性评价硫酸化糖胺聚糖寡糖并初步探讨其调控成纤维细胞功能的潜在作用机制
Choirul Anwar,Pitchurajan Krishna Perumal,Chun-Wei Tu et al.
Choirul Anwar et al.
Sulfated glycosaminoglycans derived from sturgeon cartilage exhibit unique structural features and diverse biological activities. This study investigated the chemical, structural, and wound-healing properties of sulfated glycosaminoglycans ...
Mimicking the Osteosarcoma Bone Microenvironment Using MEW-Printed PCL Scaffolds [0.03%]
基于MEW打印的PCL支架模拟骨肉瘤微环境
Chen Ye,Sabine Schulze,Richard Frank Richter et al.
Chen Ye et al.
Osteosarcoma is the most common primary malignant bone tumor, typically affecting children and adolescents during rapid growth periods. With current treatments, the five-year survival rate for metastatic or recurrent cases remains only 20-3...
In Vivo Evaluation of Conductive Biopolymer-Based 3D Bioprinted Nerve Conduit in Sciatic Nerve Injury Repair [0.03%]
基于导电生物聚合物的3D生物打印神经导管在坐骨神经损伤修复中的体内评价
Nasera Rizwana,Yogesh H S,Kaustubh Raundal et al.
Nasera Rizwana et al.
Peripheral nerve injury (PNI) is one of the most common conditions that occurs due to trauma and accidents. A successful peripheral nerve regeneration can potentially benefit from the use of conduits with adequate physical, mechanical, and ...