Fabrication of Microbeads with a Controllable Hollow Interior and Porous Wall Using a Capillary Fluidic Device [0.03%]
使用毛细管流体装置制造可控中空多孔微球
Sung-Wook Choi,Yu Zhang,Younan Xia
Sung-Wook Choi
Poly(d,l-lactide-co-glycolide) (PLGA) microbeads with a hollow interior and porous wall are prepared using a simple fluidic device fabricated with PVC tubes, glass capillaries, and a needle. Using the fluidic device with three flow channels...
Integration of a Chemical-Responsive Hydrogel into a Porous Silicon Photonic Sensor for Visual Colorimetric Readout [0.03%]
化学响应水凝胶集成 porous silicon 光子传感器的可视化比色读出技术
Lisa M Bonanno,Lisa A Delouise
Lisa M Bonanno
The incorporation of a chemo-responsive hydrogel into a 1D photonic porous silicon (PSi) transducer is demonstrated. A versatile hydrogel backbone is designed via the synthesis of an amine-functionalized polyacrylamide copolymer where furth...
PEI-PEG-Chitosan Copolymer Coated Iron Oxide Nanoparticles for Safe Gene Delivery: synthesis, complexation, and transfection [0.03%]
用于安全基因传递的PEI-PEG-CS复合物包被铁氧化纳米颗粒：合成、配位及转染
Forrest M Kievit,Omid Veiseh,Narayan Bhattarai et al.
Forrest M Kievit et al.
Gene therapy offers the potential of mediating disease through modification of specific cellular functions of target cells. However, effective transport of nucleic acids to target cells with minimal side effects remains a challenge despite ...
Porous polymer coatings: a versatile approach to superhydrophobic surfaces [0.03%]
多孔聚合物涂层：一种制备超疏水表面的通用方法
Pavel A Levkin,Frantisek Svec,Jean M J Frechet
Pavel A Levkin
We present a facile and inexpensive approach to superhydrophobic polymer coatings. The method involves the in-situ polymerization of common monomers in the presence of a porogenic solvent to afford superhydrophobic surfaces with the desired...
Controlling Affinity Binding with Peptide-Functionalized Poly(ethylene glycol) Hydrogels [0.03%]
具有肽官能化的聚（乙二醇）水凝胶的亲和结合控制
Chien-Chi Lin,Kristi S Anseth
Chien-Chi Lin
Poly(ethylene glycol) (PEG) hydrogels functionalized with peptide moieties have been widely used in regenerative medicine applications. While many studies have suggested the importance of affinity binding within PEG hydrogels, the relations...
Guided Cell Migration on Microtextured Substrates with Variable Local Density and Anisotropy [0.03%]
具有可变局部密度和各向异性的微纹理底物上的细胞迁移引导
Deok-Ho Kim,Chang-Ho Seo,Karam Han et al.
Deok-Ho Kim et al.
This work reports the design of and experimentation with a topographically patterned cell culture substrate of variable local density and anisotropy as a facile and efficient platform to guide the organization and migration of cells in spat...
Guobao Wei,Peter X Ma
Guobao Wei
Biomaterials play a pivotal role in regenerative medicine, which aims to regenerate and replace lost/dysfunctional tissues or organs. Biomaterials (scaffolds) serve as temporary 3D substrates to guide neo tissue formation and organization. ...
Conductive Core-Sheath Nanofibers and Their Potential Application in Neural Tissue Engineering [0.03%]
导电芯/sheath型纳米纤维及其在神经组织工程中的潜在应用
Jingwei Xie,Matthew R Macewan,Stephanie M Willerth et al.
Jingwei Xie et al.
We have prepared conductive core-sheath nanofibers via a combination of electrospinning and aqueous polymerization. Specifically, nanofibers electrospun from poly(ε-caprolactone) (PCL) and poly((L)-lactide) (PLA) were employed as templates...
Biological assemblies provide novel templates for the synthesis of hierarchical structures and facilitate cell adhesion [0.03%]
生物组件为等级结构的合成提供了新颖模板并促进细胞黏附
Sivakumar Gajjeraman,Gen He,Karthikeyan Narayanan et al.
Sivakumar Gajjeraman et al.
Mechanical mismatch and the lack of interactions between implants and the natural tissue environment are the major drawbacks in bone tissue engineering. Biomaterials mimicking the self-assembly process and the composition of the bone matrix...
Micropatterned Polypyrrole: A Combination of Electrical and Topographical Characteristics for the Stimulation of Cells [0.03%]
微图案聚吡咯：用于刺激细胞的电学和形貌特征的结合体
Natalia Gomez,Jae Y Lee,Jon D Nickels et al.
Natalia Gomez et al.
Electrically conducting polymers such as polypyrrole (PPy) are important biomaterials in neural engineering applications, including neural probes, nerve conduits, and scaffolds for tissue and nerve regeneration. Surface modification of thes...