3D Bioprinting Highly Elastic PEG-PCL-DA Hydrogel for Soft Tissue Fabrication and Biomechanical Stimulation [0.03%]
用于组织工程的软生物电子水凝胶的3D打印
Wenhan Lee,Cancan Xu,Huikang Fu et al.
Wenhan Lee et al.
3-D bioprinting is a promising technology to fabricate custom geometries for tissue engineering. However, most bioprintable hydrogels are weak and fragile, difficult to handle and cannot mimetic the mechanical behaviors of the native soft e...
Photosensitive Nanoprobes for Rapid Isolation and Size-Specific Enrichment of Synthetic and Extracellular Vesicle Subpopulations [0.03%]
用于合成和细胞外囊泡亚群的快速分离和尺寸特异富集的光敏纳米探针
Jonathan S Weerakkody,Tiffany Tseng,Mackenzie Topper et al.
Jonathan S Weerakkody et al.
The biggest challenge in current isolation methods for lipid bilayer-encapsulated vesicles, such as exosomes, secretory, and synthetic vesicles, lies in the absence of a unified approach that seamlessly delivers high purity, yield, and scal...
Tuneable Recombinant Spider Silk Protein Hydrogels for Drug Release and 3D Cell Culture [0.03%]
可调式重组蜘蛛丝蛋白水凝胶在药物缓释和三维细胞培养中的应用研究
Tina Arndt,Urmimala Chatterjee,Olga Shilkova et al.
Tina Arndt et al.
Hydrogels are useful drug release systems and tissue engineering scaffolds. However, synthetic hydrogels often require harsh gelation conditions and can contain toxic by-products while naturally derived hydrogels can transmit pathogens and ...
Benjamin Schmuck,Gabriele Greco,Tomas Bohn Pessatti et al.
Benjamin Schmuck et al.
Artificial spider silk is an attractive material for many technical applications since it is a biobased fiber that can be produced under ambient conditions but still outcompetes synthetic fibers (e.g., Kevlar) in terms of toughness. Industr...
Functional Nanomaterials for the Diagnosis of Alzheimer's Disease: Recent Progress and Future Perspectives [0.03%]
用于阿尔茨海默病诊断的功能纳米材料：近期进展和未来前景
Saqer Al Abdullah,Lubna Najm,Liane Ladouceur et al.
Saqer Al Abdullah et al.
Alzheimer's disease (AD) is one of the main causes of dementia worldwide, whereby neuronal death or malfunction leads to cognitive impairment in the elderly population. AD is highly prevalent, with increased projections over the next few de...
Synthetic Colonic Mucus Enables the Development of Modular Microbiome Organoids [0.03%]
合成结肠粘液能够使模块化微生物组器官体发展成为可能
Michael A Miller,Scott Medina
Michael A Miller
The human colon is home to trillions of microorganisms that modulate gastrointestinal physiology. Our understanding of how this gut ecosystem impacts human health, although evolving, has been slowed by the lack of accessible tools suitable ...
In Situ Detection of Neuroinflammation using Multi-cellular 3D Neurovascular Unit-on-a-Chip [0.03%]
基于多细胞3D神经血管单位芯片的原位检测神经炎症方法
Jin-Ha Choi,Hye Kyu Choi,Ki-Bum Lee
Jin-Ha Choi
The human neurovascular system is a complex network of blood vessels and brain cells that is essential to the proper functioning of the brain. In recent years, researchers have become increasingly interested in the role of this system in de...
Real-Time, Non-Invasive Monitoring of Neuronal Differentiation Using Intein-Enabled Fluorescence Signal Translocation in Genetically Encoded Stem Cell-Based Biosensors [0.03%]
基于基因编码干细胞生物传感器的接合蛋白荧光信号转位技术实现神经元分化的实时无创监测
Euiyeon Lee,Hye Kyu Choi,Youngeun Kwon et al.
Euiyeon Lee et al.
Real-time and non-invasive monitoring of neuronal differentiation will help increase our understanding of neuronal development and help develop regenerative stem cell therapies for neurodegenerative diseases. Traditionally, reverse transcri...
Photografting of Surface-assembled Hydrogel Prepolymers to Elastomeric Substrates for Production of Stimuli-Responsive Microlens Arrays [0.03%]
用于生产刺激响应式微透镜阵列的表面组装水凝胶 prepolymer 的光接枝技术制备具有弹性基材的刺激响应式微镜头数组
John M Kapitan,Grayson Minnick,Brennan P Watts et al.
John M Kapitan et al.
Hydrogels have emerged as prototypical stimuli-responsive materials with potential applications in soft robotics, microfluidics, tissue engineering, and adaptive optics. To leverage the full potential of these materials, fabrication techniq...
Physical and Soluble Cues Enhance Tendon Progenitor Cell Invasion into Injectable Synthetic Hydrogels [0.03%]
物理和可溶性线索增强肌腱前体细胞向可注射合成水凝胶的侵入
Robert N Kent rd,Mohamed Said,Megan E Busch et al.
Robert N Kent rd et al.
Synthetic hydrogels represent an exciting avenue in the field of regenerative biomaterials given their injectability, orthogonally tunable mechanical properties, and potential for modular inclusion of cellular cues. Separately, recent advan...