Blaine J Zern,Hunghao Chu,Adeboye O Osunkoya et al.
Blaine J Zern et al.
Self assembly between cations and anions is ubiquitous throughout nature. Important biological structures such as chromatin often use polyvalent assembly between a polycation and a polyaninon. Biomedical importance of synthetic polycations ...
Lipid-like Nanoparticles for Small Interfering RNA Delivery to Endothelial Cells [0.03%]
类似脂质的纳米颗粒用于将小干扰RNA递送至内皮细胞
Seung-Woo Cho,Michael Goldberg,Sun Mi Son et al.
Seung-Woo Cho et al.
Here we develop nanoparticles composed of lipid-like materials (lipidoids) to facilitate non-viral delivery of small interfering RNA (siRNA) to endothelial cells (ECs). Nanoparticles composed of siRNA and lipidoids with small size (~200 nm)...
Yiqian Zhu,Aijun Wang,Wenqian Shen et al.
Yiqian Zhu et al.
The difficulty in spinal cord regeneration is related to the inhibitory factors for axon growth and the lack of appropriate axon guidance in the lesion region. Here we developed scaffolds with aligned nanofibers for nerve guidance and drug ...
Tuna Yucel,Peggy Cebe,David L Kaplan
Tuna Yucel
Uniaxially oriented, piezoelectric silk films were prepared by a two-step method that involved: (1) air drying aqueous, regenerated silk fibroin solutions into films, and (2) drawing the silk films to a desired draw ratio. The utility of tw...
DNA Sensing using Nano-crystalline Surface Enhanced Al(2)O(3) Nanopore Sensors [0.03%]
基于纳米氧化铝纳米孔的DNA传感器检测
B M Venkatesan,A B Shah,J M Zuo et al.
B M Venkatesan et al.
A new solid-state, Al(2)O(3) nanopore sensor with enhanced surface properties for the real-time detection and analysis of individual DNA molecules is reported. Nanopore formation using electron beam based decomposition transformed the local...
Preparation and characterization of a pH- and thermally responsive poly(N-isopropylacrylamide-co-acrylic acid)/porous SiO(2) hybrid [0.03%]
一种pH及温度响应性的聚[N-异丙基丙烯酰胺-共- acrylic acid]/多孔二氧化硅杂化材料的制备与表征研究
Loren A Perelman,Troy Moore,Jennifer Singelyn et al.
Loren A Perelman et al.
A multifunctional nanohybrid composed of a pH- and thermoresponsive hydrogel, poly(N-isopropylacrylamide-co-acrylic acid), poly(NIPAM-co-AAc) is synthesized in-situ within the mesopores of an oxidized porous Si template. The hybrid is chara...
Porous Polymersomes with Encapsulated Gd-labeled Dendrimers as Highly Efficient MRI Contrast Agents [0.03%]
负载钆标记星形聚合物的多孔聚合物囊泡作为高效的MRI对比剂
Zhiliang Cheng,Daniel L J Thorek,Andrew Tsourkas
Zhiliang Cheng
The use of nanovesicles with encapsulated Gd as MR contrast agents has largely been ignored due to the detrimental effects of the slow water exchange rate through the vesicle bilayer on the relaxivity of encapsulated Gd. Here, we describe t...
Discoidal Porous Silicon Particles: Fabrication and Biodistribution in Breast Cancer Bearing Mice [0.03%]
盘状多孔硅微粒的制备及在乳腺癌小鼠体内的生物分布研究
Biana Godin,Ciro Chiappini,Srimeenakshi Srinivasan et al.
Biana Godin et al.
Porous silicon (pSi) is emerging as a promising material in the development of nanovectors for the systemic delivery of therapeutic and imaging agents. The integration of photolithographic patterning, typical of the semiconductor industry, ...
Yuri S Velichko,Jason R Mantei,Ronit Bitton et al.
Yuri S Velichko et al.
Self-assembly in the presence of external forces is an adaptive, directed organization of molecular components under nonequilibrium conditions. While forces may be generated as a result of spontaneous interactions among components of a syst...
Modulation of Viscoelasticity and HIV Transport as a Function of pH in a Reversibly Crosslinked Hydrogel [0.03%]
pH依赖性可逆交联水凝胶的粘弹性调控及其HIV运输性能研究
Julie I Jay,Shetha Shukair,Kristofer Langheinrich et al.
Julie I Jay et al.