Matthew J Hancock,Koray Sekeroglu,Melik C Demirel
Matthew J Hancock
In Nature, directional surfaces on insect cuticle, animal fur, bird feathers, and plant leaves are comprised of dual micro-nanoscale features that tune roughness and surface energy. This feature article summarizes experimental and theoretic...
Polymeric Aqueous Biphasic System Rehydration Facilitates High Throughput Cell Exclusion Patterning For Cell Migration Studies [0.03%]
聚合物水相分离系统促进高通量细胞图案化用于细胞迁移研究
Hossein Tavana,Kerim Kaylan,Tommaso Bersano-Begey et al.
Hossein Tavana et al.
This paper describes a cell-exclusion patterning method facilitated by a polymeric aqueous two-phase system. The immersion aqueous phase (polyethylene glycol) containing cells rehydrates a dried disk of the denser phase (dextran) on the sub...
Affinity-based Protein Surface Pattern Formation by Ligand Self-Selection from Mixed Protein Solutions [0.03%]
基于配体自选择的混合蛋白质溶液中蛋白质表面图案形成
David W Grainger,David G Castner,Manish Dubey et al.
David W Grainger et al.
Photolithographically prepared surface patterns of two affinity ligands (biotin and chloroalkane) specific for two proteins (streptavidin and HaloTag®, respectively) are used to spontaneously form high-fidelity surface patterns of the two ...
Composite dissolving microneedles for coordinated control of antigen and adjuvant delivery kinetics in transcutaneous vaccination [0.03%]
复合溶型微针递药系统实现经皮免疫接种过程中抗原和佐剂的协同控释
Peter C Demuth,Wilfredo F Garcia-Beltran,Michelle Lim Ai-Ling et al.
Peter C Demuth et al.
Transcutaneous administration has the potential to improve therapeutics delivery, providing an approach that is safer and more convenient than traditional alternatives, while offering the opportunity for improved therapeutic efficacy throug...
Antibiotic-Releasing Silk Biomaterials for Infection Prevention and Treatment [0.03%]
用于感染预防和治疗的载药抗菌丝蛋白材料研究进展
Eleanor M Pritchard,Thomas Valentin,Bruce Panilaitis et al.
Eleanor M Pritchard et al.
Effective treatment of infections in avascular and necrotic tissues can be challenging due to limited penetration into the target tissue and systemic toxicities. Controlled release polymer implants have the potential to achieve the high loc...
pH-Based Regulation of Hydrogel Mechanical Properties Through Mussel-Inspired Chemistry and Processing [0.03%]
基于pH的利用受贻贝启发的化学和加工调节水凝胶力学性能
Devin G Barrett,Dominic E Fullenkamp,Lihong He et al.
Devin G Barrett et al.
The mechanical holdfast of the mussel, the byssus, is processed at acidic pH yet functions at alkaline pH. Byssi are enriched in Fe3+ and catechol-containing proteins, species with chemical interactions that vary widely over the pH range of...
Rapid and Facile Microwave-Assisted Surface Chemistry for Functionalized Microarray Slides [0.03%]
一种快速简易的微波表面化学技术制备多功能芯片基片
Jeong Heon Lee,Hoon Hyun,Conor J Cross et al.
Jeong Heon Lee et al.
We describe a rapid and facile method for surface functionalization and ligand patterning of glass slides based on microwave-assisted synthesis and a microarraying robot. Our optimized reaction enables surface modification 42-times faster t...
Assemblies of Functional Peptides and Their Applications in Building Blocks for Biosensors [0.03%]
功能肽的组装及其在生物传感器构筑块中的应用
Roberto de la Rica,Christophe Pejoux,Hiroshi Matsui
Roberto de la Rica
We highlight our recent applications of functional peptide nanotubes, self-assembled from short peptides with recognition elements, as building blocks to develop sensors. Peptide nanotubes with high aspect ratios are excellent building bloc...
Preparation and Characterization of Molecularly Imprinted Polymeric Nanoparticles for Atrial Natriuretic Peptide (ANP) [0.03%]
用于心房利钠肽的分子印迹聚合物纳米粒子的制备及表征
Chunyan Wang,Mark Howell,Payal Raulji et al.
Chunyan Wang et al.
Natriuretic peptide receptor A (NPRA), the receptor for the cardiac hormone atrial natriuretic peptide (ANP), is expressed abundantly on cancer cells and disruption of ANP-NPRA signaling inhibits tumor burden and metastasis. Since antagonis...
Polyglycerol-Dendronized Perylenediimides as Stable, Water-Soluble Fluorophores [0.03%]
稳定的水溶性荧光聚甘油-树枝状perylenediimides化合物
Si Kyung Yang,Steven C Zimmerman
Si Kyung Yang
The synthesis and photophysical properties of water-soluble, fluorescent polyglycerol-dendronized perylenediimides 1-4 are reported. The polyglycerol dendrons, which are known to be highly biocompatible, are found to confer high water-solub...