Han L Lim,Jessica C Chuang,Tuan Tran et al.
Han L Lim et al.
Hydrogels have numerous biomedical applications including synthetic matrices for cell culture and tissue engineering. Here we report the development of hydrogel based multifunctional matrices that not only provide three-dimensional structur...
Encapsulating Elastically Stretchable Neural Interfaces: Yield, Resolution, and Recording/Stimulation of Neural Activity [0.03%]
封装弹性可拉伸神经接口：产量、分辨率和记录/刺激神经活动
Oliver Graudejus,Barclay Morrison rd,Cezar Goletiani et al.
Oliver Graudejus et al.
A high resolution elastically stretchable microelectrode array (SMEA) to interface with neural tissue is described. The SMEA consists of an elastomeric substrate, such as poly(dimethylsiloxane) (PDMS), elastically stretchable gold conductor...
Tuning the Poisson's Ratio of Biomaterials for Investigating Cellular Response [0.03%]
调节生物材料的泊松比以研究细胞响应
Wande Zhang,Pranav Soman,Kyle Meggs et al.
Wande Zhang et al.
Cells sense and respond to mechanical forces, regardless of whether the source is from a normal tissue matrix, an adjacent cell or a synthetic substrate. In recent years, cell response to surface rigidity has been extensively studied by mod...
Slowly degradable porous silk microfabricated scaffolds for vascularized tissue formation [0.03%]
用于血管组织构建的可降解多孔丝蛋白微支架
Lindsay S Wray,Konstantinos Tsioris,Eun Seok Gi et al.
Lindsay S Wray et al.
There is critical clinical demand for tissue-engineered (TE), three-dimensional (3D) constructs for tissue repair and organ replacements. Current efforts toward this goal are prone to necrosis at the core of larger constructs because of lim...
Focal Infection Treatment using Laser-Mediated Heating of Injectable Silk Hydrogels with Gold Nanoparticles [0.03%]
载金纳米颗粒的可注射丝素水凝胶激光介导局部热疗聚焦感染治疗
Nikola Kojic,Eleanor M Pritchard,Hu Tao et al.
Nikola Kojic et al.
Medical treatment of subcutaneous bacterial abscesses usually involves systemic high-dose antibiotics and incision-drainage of the wound. Such an approach suffers from two main deficiencies: bacterial resistance to antibiotics and pain asso...
Hot Spot-Localized Artificial Antibodies for Label-Free Plasmonic Biosensing [0.03%]
热点定位人工抗体用于无标记等离子生物传感
Abdennour Abbas,Limei Tian,Jeremiah J Morrissey et al.
Abdennour Abbas et al.
The development of biomolecular imprinting over the last decade has raised promising perspectives in replacing natural antibodies with artificial antibodies. A significant number of reports have been dedicated to imprinting of organic and i...
Ellipsoidal Polyaspartamide Polymersomes with Enhanced Cell-Targeting Ability [0.03%]
椭球体多聚天冬氨酸聚合物囊泡的细胞靶向能力增强
Mei-Hsiu Lai,Jae Hyun Jeong,Ross J Devolder et al.
Mei-Hsiu Lai et al.
Nano-sized polymersomes functionalized with peptides or proteins are being increasingly studied for targeted delivery of diagnostic and therapeutic molecules. Earlier computational studies have suggested that ellipsoidal nanoparticles, comp...
Synergetic Targeted Delivery of Sleeping-Beauty Transposon System to Mesenchymal Stem Cells Using LPD Nanoparticles Modified with a Phage-Displayed Targeting Peptide [0.03%]
利用噬菌体展示靶向肽修饰的LPD纳米粒协同递送睡眠波转座系统到间充质干细胞中
Kun Ma,Dong-Dong Wang,Yiyang Lin et al.
Kun Ma et al.
An important criterion for effective gene therapy is sufficient chromosomal integration activity. The Sleeping Beauty (SB) transposon system is a plasmid system allowing efficient insertion of transgenes into the host genome. However, such ...
Heather A Currie,Olivier Deschaume,Rajesh R Naik et al.
Heather A Currie et al.
Digital Inverter Amine Sensing via Synergistic Responses by n and p Organic Semiconductors [0.03%]
基于有机半导体协同响应的数字反相胺传感
Noah J Tremblay,Byung Jun Jung,Patrick Breysse et al.
Noah J Tremblay et al.
Chemiresistors and sensitive OFETs have been substantially developed as cheap, scalable, and versatile sensing platforms. While new materials are expanding OFET sensing capabilities, the device architectures have changed little. Here we rep...