Targeting of Cancer Cells Using Quantum Dot-Polypeptide Hybrid Assemblies that Function as Molecular Imaging Agents and Carrier Systems [0.03%]
一种分子影像剂和载体系统：用于靶向癌症细胞的量子点-多肽杂化组装体
Bayu Atmaja,Bertrand H Lui,Yuhua Hu et al.
Bayu Atmaja et al.
We report a highly tunable quantum dot (QD)-polypeptide hybrid assembly system with potential uses for both molecular imaging and delivery of biomolecular cargo to cancer cells. In this work, we demonstrate the tunability of the assembly sy...
Theranostic USPIO-Loaded Microbubbles for Mediating and Monitoring Blood-Brain Barrier Permeation [0.03%]
兼具治疗和诊断功能的USPIO载药微气泡介导并监测血脑屏障通透性
Twan Lammers,Patrick Koczera,Stanley Fokong et al.
Twan Lammers et al.
Efficient and safe drug delivery across the blood-brain barrier (BBB) remains to be one of the major challenges of biomedical and (nano-) pharmaceutical research. Here, we show that poly(butyl cyanoacrylate)-based microbubbles (MB), carryin...
Reinforcement of Shear Thinning Protein Hydrogels by Responsive Block Copolymer Self-Assembly [0.03%]
响应型嵌段共聚物自组装增强剪切变稀蛋白水凝胶性能
Matthew J Glassman,Jacqueline Chan,Bradley D Olsen
Matthew J Glassman
Shear thinning hydrogels are promising materials that exhibit rapid self-healing following the cessation of shear, making them attractive for a variety of applications including injectable biomaterials. In this work, self-assembly is demons...
Polymeric Multilayers that contain Silver Nanoparticles can be Stamped onto Biological Tissues to Provide Antibacterial Activity [0.03%]
可印刷到生物组织上的银纳米粒子聚合物多层膜及其抗菌性能
Ankit Agarwal,Kathleen M Guthrie,Charles J Czuprynski et al.
Ankit Agarwal et al.
We report the design of polyelectrolyte multilayers (PEMs) that can be prefabricated on an elastomeric stamp and mechanically transferred onto biomedically-relevant soft materials, including medical-grade silicone elastomers (E'~450-1500 kP...
Capillary Network-Like Organization of Endothelial Cells in PEGDA Scaffolds Encoded with Angiogenic Signals via Triple Helical Hybridization [0.03%]
基于三螺旋杂交编码血管生成信号的PEGDA支架中内皮细胞的毛细血管网络化组织研究
Patrick J Stahl,Tania R Chan,Yu-I Shen et al.
Patrick J Stahl et al.
Deconstructing the Effects of Matrix Elasticity and Geometry in Mesenchymal Stem Cell Lineage Commitment [0.03%]
基质弹性和几何形貌对间充质干细胞分化命运影响的研究
Greg M Harris,Maria E Piroli,Ehsan Jabbarzadeh
Greg M Harris
A wide variety of environmental factors including physical and biochemical signals are responsible for stem cell behavior and function. In particular, matrix elasticity and cell shape have been shown to determine stem cell function, yet lit...
Gold-Coated Fe3O4 Nanoroses with Five Unique Functions for Cancer Cell Targeting, Imaging and Therapy [0.03%]
具有五种独特功能的金涂层Fe3O4纳米玫瑰用于癌症细胞靶向、成像和治疗
Chunmei Li,Tao Chen,Ismail Ocsoy et al.
Chunmei Li et al.
The development of nanomaterials that combine diagnostic and therapeutic functions within a single nanoplatform is extremely important for molecular medicine. Molecular imaging with simultaneous diagnosis and therapy will provide the multim...
Improved Exciton Dissociation at Semiconducting Polymer:ZnO Donor:Acceptor Interfaces via Nitrogen Doping of ZnO [0.03%]
通过氮掺杂改善聚合物:锌氧化物给体-受体界面的激子解离
Kevin P Musselman,Sebastian Albert-Seifried,Robert L Z Hoye et al.
Kevin P Musselman et al.
Exciton dissociation at the zinc oxide/poly(3-hexylthiophene) (ZnO/P3HT) interface as a function of nitrogen doping of the zinc oxide, which decreases the electron concentration from approximately 1019 cm-3 to 1017 cm-3, is reported. Excito...
DNA Hybridization-Mediated Liposome Fusion at the Aqueous Liquid Crystal Interface [0.03%]
基于DNA杂交的水相液晶界面上的脂质体融合效应研究
Patrick S Noonan,Praveena Mohan,Andrew P Goodwin et al.
Patrick S Noonan et al.
The prominence of receptor-mediated bilayer fusion in cellular biology motivates development of biomimetic strategies for studying fusogenic mechanisms. An approach is reported here for monitoring receptor-mediated fusion that exploits the ...
High Throughput Screening of Dynamic Silk-Elastin-Like Protein Biomaterials [0.03%]
用于动态丝弹性蛋白样生物材料的高通量筛选
Qin Wang,Xiaoxia Xia,Wenwen Huang et al.
Qin Wang et al.
The need for dynamic, elastomeric polymeric biomaterials remains high, with few options with tunable control of mechanical properties, and environmental responses. Yet the diversity of these types of protein polymers pursued for biomaterial...