Stimuli-Responsive Materials for Controlled Release of Theranostic Agents [0.03%]
用于治疗诊断药物控制释放的刺激响应材料
Yucai Wang,Min Suk Shim,Nathanael S Levinson et al.
Yucai Wang et al.
Stimuli-responsive materials are so named because they can alter their physicochemical properties and/or structural conformations in response to specific stimuli. The stimuli can be internal, such as physiological or pathological variations...
Adopting the principles of collagen biomineralization for intrafibrillar infiltration of yttria-stabilized zirconia into three-dimensional collagen scaffolds [0.03%]
采用胶原生物矿化原理将氧化钇稳定的四氧化锆渗入三维胶原支架中
Bin Zhou,Li-Na Niu,Wei Shi et al.
Bin Zhou et al.
In this paper, we report a process for generating collagen-yttria-stabilized amorphous zirconia hybrid scaffolds by introducing acetylacetone-inhibited zirconia precursor nanodroplets into a poly(allylamine)-coated collagen matrix. This pol...
Cell-tethered ligands modulate bone remodeling by osteoblasts and osteoclasts [0.03%]
骨髓细胞通过破骨细胞和成骨细胞调节骨骼重塑
Rebecca S Hayden,Jean-Philippe Fortin,Benjamin Harwood et al.
Rebecca S Hayden et al.
The goals of the present study are to establish an in vitro co-culture model of osteoblast and osteoclast function and to quantify the resulting bone remodeling. The bone is tissue engineered using well-defined silk protein biomaterials in ...
Layer-by-layer assembly of 3D tissue constructs with functionalized graphene [0.03%]
功能化石墨烯的分层组装构建具有生物活性的三维组织模型
Su Ryon Shin,Behnaz Aghaei-Ghareh-Bolagh,Xiguang Gao et al.
Su Ryon Shin et al.
Carbon-based nanomaterials have been considered as promising candidates to mimic certain structure and function of native extracellular matrix materials for tissue engineering. Significant progress has been made in fabricating carbon nanopa...
Flipping the Switch on Clathrin-Mediated Endocytosis using Thermally Responsive Protein Microdomains [0.03%]
采用温度响应蛋白微区控制 clathrin 介导的胞吞作用
Martha K Pastuszka,Curtis T Okamoto,Sarah F Hamm-Alvarez et al.
Martha K Pastuszka et al.
A ubiquitous approach to study protein function is to knock down activity (gene deletions, siRNA, small molecule inhibitors, etc) and study the cellular effects. Using a new methodology, this manuscript describes how to rapidly and specific...
Núria Marí-Buyé,Shannan O&#x;Shaughnessy,Carles Colominas et al.
Núria Marí-Buyé et al.
This paper reports the design, synthesis and characterization of thin films as a platform for studying the separate influences of physical and chemical cues of a matrix on the adhesion, growth and final phenotype of cells. Independent contr...
High Throughput, Polymeric Aqueous Two-Phase Printing of Tumor Spheroids [0.03%]
高通量聚合物水相双嵌印制肿瘤类器官球体技术
Ehsan Atefi,Stephanie Lemmo,Darcy Fyffe et al.
Ehsan Atefi et al.
This paper presents a new 3D culture microtechnology for high throughput production of tumor spheroids and validates its utility for screening anti-cancer drugs. We use two immiscible polymeric aqueous solutions and microprint a submicrolit...
Composite Living Fibers for Creating Tissue Constructs Using Textile Techniques [0.03%]
基于纺织技术构建组织工程移植物的复合连续纤维研究进展
Mohsen Akbari,Ali Tamayol,Veronique Laforte et al.
Mohsen Akbari et al.
The fabrication of cell-laden structures with anisotropic mechanical properties while having a precise control over the distribution of different cell types within the constructs is important for many tissue engineering applications. Automa...
Controlled Generation of Microspheres Incorporating Extracellular Matrix Fibrils for Three-Dimensional Cell Culture [0.03%]
一种用于三维细胞培养的包含细胞外基质纤维的微球的可控生成方法
Victoria L Workman,Liku B Tezera,Paul T Elkington et al.
Victoria L Workman et al.
A growing body of evidence suggests that studying cell biology in classical two-dimensional formats, such as cell culture plasticware, results in misleading, non-physiological findings. For example, some aspects of cancer biology cannot be ...
Primary Neuron/Astrocyte Co-Culture on Polyelectrolyte Multilayer Films: A Template for Studying Astrocyte-Mediated Oxidative Stress in Neurons [0.03%]
基于聚电解质多层膜的原代神经元/星形胶质细胞共培养体系：研究星形胶质细胞介导的神经元氧化应激的模型
Srivatsan Kidambi,Ilsoon Lee,Christina Chan
Srivatsan Kidambi
We engineered patterned co-cultures of primary neurons and astrocytes on polyelectrolyte multilayer (PEM) films without the aid of adhesive proteins/ligands to study the oxidative stress mediated by astrocytes on neuronal cells. A number of...