Facile One-step Micropatterning Using Photodegradable Methacrylated Gelatin Hydrogels for Improved Cardiomyocyte Organization and Alignment [0.03%]
一种使用光降解的甲基丙烯酸明胶水凝胶一步微图案化制备改善心肌细胞组织和对齐的方法
Kelly M C Tsang,Nasim Annabi,Francesca Ercole et al.
Kelly M C Tsang et al.
Hydrogels are often employed as temporary platforms for cell proliferation and tissue organization in vitro. Researchers have incorporated photodegradable moieties into synthetic polymeric hydrogels as a means of achieving spatiotemporal co...
In Situ Crosslinkable Gelatin Hydrogels for Vasculogenic Induction and Delivery of Mesenchymal Stem Cells [0.03%]
原位交联胶原水凝胶诱导血管化并递送间充质干细胞
Sue Hyun Lee,Yunki Lee,Young Wook Chun et al.
Sue Hyun Lee et al.
Clinical trials utilizing mesenchymal stem cells (MSCs) for severe vascular diseases have highlighted the need to effectively engraft cells and promote pro-angiogenic activity. A functional material accomplishing these two goals is an ideal...
Matrix-Bound VEGF Mimetic Peptides: Design and Endothelial Cell Activation in Collagen Scaffolds [0.03%]
基质约束的VEGF模拟多肽的设计及其在胶原支架中对内皮细胞活化的调控作用
Tania R Chan,Patrick J Stahl,S Michael Yu
Tania R Chan
Long term survival and success of artificial tissue constructs depend greatly on vascularization. Endothelial cell (EC) differentiation and vasculature formation are dependent on spatio-temporal cues in the extracellular matrix that dynamic...
MRI/SPECT/Fluorescent Tri-Modal Probe for Evaluating the Homing and Therapeutic Efficacy of Transplanted Mesenchymal Stem Cells in a Rat Ischemic Stroke Model [0.03%]
评估移植间充质干细胞在缺血卒中大鼠模型中归巢及治疗效果的MRI/SPECT/荧光三模态示踪剂
Yaohui Tang,Chunfu Zhang,Jixian Wang et al.
Yaohui Tang et al.
Quantitatively tracking engraftment of intracerebrally or intravenously transplanted stem cells and evaluating their concomitant therapeutic efficacy for stroke has been a challenge in the field of stem cell therapy. In this study, first, a...
Multifunctional Dendrimer-templated Antibody Presentation on Biosensor Surfaces for Improved Biomarker Detection [0.03%]
基于仿生传感器表面的多齿树形分子模板抗体阵列用于改善生物标志物的检测性能
Hye Jung Han,Rangaramanujam M Kannan,Sunxi Wang et al.
Hye Jung Han et al.
Dendrimers, with their well-defined globular shape and a high density of functional groups, are ideal nanoscale materials for templating sensor surfaces. This work exploits dendrimers as a versatile platform for capturing biomarkers with im...
Injectable Hydrogels with In Situ Double Network Formation Enhance Retention of Transplanted Stem Cells [0.03%]
原位双网络水凝胶促进移植干细胞的滞留注射液
Lei Cai,Ruby E Dewi,Sarah C Heilshorn
Lei Cai
Electrostatically Directed Self-Assembly of Ultrathin Supramolecular Polymer Microcapsules [0.03%]
静电导向自装超薄聚合物微胶囊
Richard M Parker,Jing Zhang,Yu Zheng et al.
Richard M Parker et al.
Supramolecular self-assembly offers routes to challenging architectures on the molecular and macroscopic scale. Coupled with microfluidics it has been used to make microcapsules-where a 2D sheet is shaped in 3D, encapsulating the volume wit...
Room Temperature Ferrimagnetism and Ferroelectricity in Strained, Thin Films of BiFe0.5Mn0.5O3 [0.03%]
在应变BiFe0.5Mn0.5O3薄膜中室温反铁磁性和铁电性的共存
Eun-Mi Choi,Thomas Fix,Ahmed Kursumovic et al.
Eun-Mi Choi et al.
Highly strained films of BiFe0.5Mn0.5O3 (BFMO) grown at very low rates by pulsed laser deposition were demonstrated to exhibit both ferrimagnetism and ferroelectricity at room temperature and above. Magnetisation measurements demonstrated f...
Delivery of iPS-NPCs to the Stroke Cavity within a Hyaluronic Acid Matrix Promotes the Differentiation of Transplanted Cells [0.03%]
透明质酸基质递送iPSC源神经祖细胞治疗卒中促进移植物分化
Jonathan Lam,William E Lowry,S Thomas Carmichael et al.
Jonathan Lam et al.
Stroke is the leading cause of adult disability with ~80% being ischemic. Stem cell transplantation has been shown to improve functional recovery. However, the overall survival and differentiation of these cells is still low. The infarct ca...
Micropatterning Alginate Substrates for in vitro Cardiovascular Muscle on a Chip [0.03%]
微图案海藻酸盐基质用于芯片上的工程心血管肌片
Ashutosh Agarwal,Yohan Farouz,Alexander Peyton Nesmith et al.
Ashutosh Agarwal et al.
Soft hydrogels such as alginate are ideal substrates for building muscle in vitro because they have structural and mechanical properties close to the in vivo extracellular matrix (ECM) network. However, hydrogels are generally not amenable ...