Mengxi Wu,Zhangming Mao,Kejie Chen et al.
Mengxi Wu et al.
The separation of nanoscale particles based on their differences in size is an essential technique to the nanoscience and nanotechnology community. Here, nanoparticles are successfully separated in a continuous flow by using tilted-angle st...
Multifunctional Photonics Nanoparticles for Crossing the Blood-Brain Barrier and Effecting Optically Trackable Brain Theranostics [0.03%]
用于穿越血脑屏障并实现可光学追踪脑诊疗的多功能光子学纳米颗粒
Ajay Singh,Woong Kim,Youngsun Kim et al.
Ajay Singh et al.
Theranostic photonic nanoparticles (TPNs) that cross the blood-brain barrier (BBB) and efficiently deliver a therapeutic agent to treat brain diseases, simultaneously providing optical tracking of drug delivery and release, are introduced. ...
Multifunctional Molecular Beacon Micelles for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug-Resistant Cancer Cells [0.03%]
用于多药耐药癌细胞内mRNA成像和协同治疗的多功能分子信标型胶束
Ruili Zhang,Shi Gao,Zhongliang Wang et al.
Ruili Zhang et al.
Multidrug resistance (MDR) resulting from overexpression of P-glycoprotein (Pgp) transporters increases the drug efflux and thereby limits the chemotherapeutic efficacy. It is desirable to administer both an MDR1 gene silencer and a chemoth...
Designing Thin, Ultrastretchable Electronics with Stacked Circuits and Elastomeric Encapsulation Materials [0.03%]
用于超拉伸电子器件的堆叠式电路和弹性封装材料的设计
Renxiao Xu,Jung Woo Lee,Taisong Pan et al.
Renxiao Xu et al.
Many recently developed soft, skin-like electronics with high performance circuits and low modulus encapsulation materials can accommodate large bending, stretching, and twisting deformations. Their compliant mechanics also allows for intim...
Biocompatible D-A Semiconducting Polymer Nanoparticle with Light-Harvesting Unit for Highly Effective Photoacoustic Imaging Guided Photothermal Therapy [0.03%]
具有光收集单元的生物相容性D-A半导体聚合物纳米粒子用于高效的 photoacoustic成像引导的光热治疗
Jinfeng Zhang,Caixia Yang,Rui Zhang et al.
Jinfeng Zhang et al.
The development of nanotheranostic agents that integrate diagnosis and therapy for effective personalized precision medicine has obtained tremendous attention in the past few decades. In this report, biocompatible electron donor-acceptor co...
Design of Strain-Limiting Substrate Materials for Stretchable and Flexible Electronics [0.03%]
应变限制基底材料的设计用于可拉伸和柔性电子设备
Yinji Ma,Kyung-In Jang,Liang Wang et al.
Yinji Ma et al.
Recently developed classes of electronics for biomedical applications exploit substrates that offer low elastic modulus and high stretchability, to allow intimate, mechanically biocompatible integration with soft biological tissues. A chall...
Chemical Sensing Systems that Utilize Soft Electronics on Thin Elastomeric Substrates with Open Cellular Designs [0.03%]
基于薄开孔弹性基底软电子的化学检测系统
Yoon Kyeung Lee,Kyung-In Jang Prof,Yinji Ma et al.
Yoon Kyeung Lee et al.
A collection of materials and device architectures are introduced for thin, stretchable arrays of ion sensors that mount on open cellular substrates to facilitate solution exchange for use in biointegrated electronics. The results include i...
Neuroendocrine Tumor-Targeted Upconversion Nanoparticle-Based Micelles for Simultaneous NIR-Controlled Combination Chemotherapy and Photodynamic Therapy, and Fluorescence Imaging [0.03%]
基于纳米粒子的聚合物胶束用于神经内分泌肿瘤同时治疗及成像：近红外光控制的联合化疗、光动力疗法和荧光影像引导手术切除肿瘤
Guojun Chen,Renata Jaskula-Sztul,Corinne R Esquibel et al.
Guojun Chen et al.
Although neuroendocrine tumors (NETs) are slow growing, they are frequently metastatic at the time of discovery and no longer amenable to curative surgery, emphasizing the need for the development of other treatments. In this study, multifu...
Glycine N-methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing [0.03%]
NGR标记型纳米载体中的甘氨酸N甲基化可防止异天冬酰胺形成和整合素结合而不影响CD13识别及肿瘤归巢作用
Angelo Corti,Anna Maria Gasparri,Michela Ghitti et al.
Angelo Corti et al.
NGR (asparagine-glycine-arginine) is a tumor vasculature-homing peptide motif widely used for the functionalization of drugs, nanomaterials and imaging compounds for cancer treatment and diagnosis. Unfortunately, this motif has a strong pro...
Engineered elastomer substrates for guided assembly of complex 3D mesostructures by spatially nonuniform compressive buckling [0.03%]
通过空间非均匀压缩失稳引导组装复杂三维宏结构的工程弹性体基底
Kewang Nan,Haiwen Luan,Zheng Yan et al.
Kewang Nan et al.
Approaches capable of creating three-dimensional (3D) mesostructures in advanced materials (device-grade semiconductors, electroactive polymers etc.) are of increasing interest in modern materials research. A versatile set of approaches exp...