Delivery of Angiogenic Therapy from Flowable Hyaluronic Acid Porous Scaffolds Results in Functional Improvement without Anti-Inflammatory Agents [0.03%]
无需抗炎剂的血管生成疗法的递送使功能得到改善
Kevin Erning,Katrina L Wilson,Cara S Smith et al.
Kevin Erning et al.
Ischemic stroke, a blockage in the vasculature of the brain that results in insufficient blood flow, is one of the world's leading causes of disability. The cascade of inflammation and cell death that occurs immediately following stroke dri...
Cold Quad-Modal Nanocomplex for Precise and Quantitative In Vivo Stem Cell Tracking [0.03%]
用于精确和定量体内干细胞追踪的冷四模态纳米复合物
Ali Shakeri-Zadeh,Chao Wang,Shreyas Kuddannaya et al.
Ali Shakeri-Zadeh et al.
Current single imaging modalities typically lack the ability to simultaneously offer detailed anatomical visualization and quantitative cellular information, which is crucial for evaluating and improving therapeutic efficacy. This work deve...
Multifunctional Nanovaccine Sensitizes Breast Cancer to Immune Checkpoint Therapy [0.03%]
多功能纳米疫苗使乳腺癌对免疫检查点疗法敏感
Carina Peres,Ana I Matos,Bárbara Carreira et al.
Carina Peres et al.
Breast cancer is the primary cause of cancer-related death in women worldwide. Breast cancer subtypes are characterized by different gene expression patterns, which drive their prognostic factors and therapeutic options. Among them, triple-...
The Synergy of Artificial Intelligence and 3D Bioprinting: Unlocking New Frontiers in Precision and Tissue Fabrication [0.03%]
人工智能与3D生物打印的协同作用：精准制造和组织构建的新前沿
Joao Vitor Silva Robazzi,I Deniz Derman,Deepak Gupta et al.
Joao Vitor Silva Robazzi et al.
This Review examines the transformative role of artificial intelligence (AI) in 3D bioprinting, focusing on how advanced AI technologies enhance its precision, functionality, and scalability. AI, through branches, such as machine learning (...
Wenting Shi,Ying Xi,Xinyi Sheng et al.
Wenting Shi et al.
Injectable hydrogels represent a promising strategy for the extended release of biological molecules, thereby reducing the frequency of injections. This study introduces a novel system based on Michael addition of dextran and polyethylene g...
High-Throughput Microfluidic-Mediated Assembly of Layer-by-Layer Nanoparticles [0.03%]
一种高通量的基于微流体技术逐层组装纳米粒子的方法
Ivan S Pires,Ezra Gordon,Heikyung Suh et al.
Ivan S Pires et al.
Surface modification of nanoparticles (NPs) via the layer-by-layer (LbL) technique is a promising approach to generate targeted drug delivery vehicles. LbL-NPs have been successfully used in preclinical models for controlled drug release, t...
Naveen R Natesh,Shyni Varghese
Naveen R Natesh
The field of cancer biology and therapeutics has soared in the past several decades with new therapeutic modalities and options for patients, such as chemoradiotherapy, immunotherapy, and combination therapy. This dramatic success in expand...
Nano-Biosensors for mRNA-Based Cell Sorting Using Intracellular Markers at the Early Stage of Cell Reprogramming [0.03%]
基于mRNA的细胞重编程早期阶段使用胞内标志物的纳米生物传感器细胞分选法
Yang Song,Jennifer Soto,Xiao Lin et al.
Yang Song et al.
Cell reprogramming and manufacturing have broad applications in tissue regeneration and disease treatment. However, many derived cell types lack unique cell surface markers for protein-based cell sorting, making it difficult to isolate thes...
Glucose-Facilitated Nanomicelles Cross Peripheral Nerve Barriers to Achieve Drug Delivery to Nerves [0.03%]
葡萄糖介导的纳米胶束跨周围神经屏障实现神经药物输送
Xiaoyan Ma,Yuhao Cai,Sumiran Kumar Gurung et al.
Xiaoyan Ma et al.
Injecting nerve-blocking agents near peripheral nerves is a clinical option for treating post-operative and chronic pain. However, the peripheral nerve barriers (PNBs) pose a physiological barrier that hinders the permeation of nerve-blocki...
Hannah S Theriault,Hannah R C Kimmel,Alison C Nunes et al.
Hannah S Theriault et al.
The initiation of endometriotic lesions is not well understood or characterized because endometriosis is typically diagnosed at an advanced stage. Endometriotic lesions are most often found on pelvic tissues and organs, especially the ovari...