Synthetic photoresponsive hydrogels enable in situ control over murine intestinal monolayer differentiation and crypt formation [0.03%]
合成光响应水凝胶能够实现对鼠肠上皮单层分化和隐窝形成进行原位控制
Mark W Young,Colter E Oroke,Bruce E Kirkpatrick et al.
Mark W Young et al.
As a model of the intestinal epithelium, intestinal stem cells (ISCs) have been grown and differentiated as monolayers on materials where stochastic organization of the crypt and villi cells occurs. We developed an allyl sulfide crosslinked...
N-Dihydrogalactochitosan Drives Conventional and Alternative Activations of STING to Synergize Type I IFN and IL-1β Productions for Antitumor Immunity [0.03%]
N-二氢半乳糖壳寡糖驱动STING的常规和替代激活作用协同促进I型干扰素和IL-1β产生以增强抗肿瘤免疫反应
Ashley R Hoover,Kaili Liu,Coline Furrer et al.
Ashley R Hoover et al.
N-dihydrogalactochitosan (GC) is an immune stimulant/adjuvant. Synthesized from chitosan and galactose, GC is a new chemical entity that significantly enhances the immune-stimulating properties of its parental material, chitosan, making it ...
Ranking Magnetic Colloid Performance for Magnetic Particle Imaging and Magnetic Particle Hyperthermia [0.03%]
磁性颗粒成像和磁性颗粒热疗用磁性溶胶性能的评价
Hayden Carlton,Marzieh Salimi,Nageshwar Arepally et al.
Hayden Carlton et al.
Magnetic particle imaging (MPI) is an emerging modality that can address longstanding technological challenges encountered with magnetic particle hyperthermia (MPH) cancer therapy. MPI is a tracer technology compatible with MPH for which ma...
Biomedical Metal-Organic Framework Materials: Perspectives and Challenges [0.03%]
biomedical metal-有机框架材料：展望与挑战
Alec Wang,Madeline Walden,Romy Ettlinger et al.
Alec Wang et al.
Metal-organic framework (MOF) materials are gaining significant interest in biomedical research, owing to their high porosity, crystallinity, and structural and compositional diversity. Their versatile hybrid organic/inorganic chemistry end...
Ruixuan Wang,Tong Qiu,Yujing Zhang et al.
Ruixuan Wang et al.
Flexible and stretchable strain sensors are in high demand in sports performance monitoring, structural health monitoring, and biomedical applications. However, existing stretchable soft sensors, primarily based on soft polymer materials, o...
Dual Infrared 2-Photon Microscopy Achieves Minimal Background Deep Tissue Imaging in Brain and Plant Tissues [0.03%]
基于双红外二次谐波产生的深组织无自体荧光光学显微成像技术
Mohammad Moein Safaee,Ian R McFarlane,Shoichi Nishitani et al.
Mohammad Moein Safaee et al.
Traditional deep fluorescence imaging has primarily focused on red-shifting imaging wavelengths into the near-infrared (NIR) windows or implementation of multi-photon excitation approaches. Here, we combine the advantages of NIR and multiph...
"Reactive" Chemical Strategy to Attain Substrate Independent " Liquid-Like" Omniphobic Solid Anti-Biofouling Coatings [0.03%]
“反应型”化学策略制备不受底物限制的全疏液态防污涂层
Arpita Shome,Isabel Martinez,Vicente D Pinon et al.
Arpita Shome et al.
Covalent and defect-free surface-grafted solid lubricating chains that can impart 'liquid-like' slippery behavior have proven advantageous over lubricant infused and textured anti-wetting surfaces. Herein, the co-hydrolysis and co-condensat...
Covalent Attachment of Horseradish Peroxidase to Single-Walled Carbon Nanotubes for Hydrogen Peroxide Detection [0.03%]
辣根过氧化物酶共价连接到单壁碳纳米管用于检测过氧化氢
Francis Ledesma,Shoichi Nishitani,Francis J Cunningham et al.
Francis Ledesma et al.
Single-walled carbon nanotubes (SWCNTs) are desirable nanoparticles for sensing biological analytes due to their photostability and intrinsic near-infrared fluorescence. Previous strategies for generating SWCNT nanosensors have leveraged no...
Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering [0.03%]
用于原位嵌合抗原受体单核细胞工程的氧化型mRNA脂质纳米颗粒
Alvin J Mukalel,Alex G Hamilton,Margaret M Billingsley et al.
Alvin J Mukalel et al.
Chimeric antigen receptor (CAR) monocyte and macrophage therapies are promising solid tumor immunotherapies that can overcome the challenges facing conventional CAR T cell therapy. mRNA lipid nanoparticles (mRNA-LNPs) offer a viable platfor...
Device Design and Advanced Computed Tomography of 3D Printed Radiopaque Composite Scaffolds and Meniscus [0.03%]
基于CT的三维打印复合材料半月板支架器件设计及性能研究
Mitchell Delemeester,Kendell M Pawelec,Jeremy M L Hix et al.
Mitchell Delemeester et al.
3D printed biomaterial implants are revolutionizing personalized medicine for tissue repair, especially in orthopedics. In this study, a radiopaque bismuth oxide (Bi2O3) doped polycaprolactone (PCL) composite is developed and implemented to...