Yu Wang,Jin Guo,Liang Zhou et al.
Yu Wang et al.
Animal silks are built from pure protein components and their mechanical performance, such as strength and toughness, often exceed most engineered materials. The secret to this success is their unique nanoarchitectures that are formed throu...
Jonathan M Grasman,Julia A Ferreira,David L Kaplan
Jonathan M Grasman
Development and maturation of vascular and neuronal tissues occurs simultaneously in utero, and are regulated by significant crosstalk. We report on the development of a 3D tissue system to model neurogenesis and recapitulate developmental ...
Coding cell micropatterns through peptide inkjet printing for arbitrary biomineralized architectures [0.03%]
基于肽的微电子打印技术构建任意仿生矿化结构
Jin Guo,Shengjie Ling,Wenyi Li et al.
Jin Guo et al.
Well-designed micropatterns present in native tissues and organs involve changes in extracellular matrix compositions, cell types and mechanical properties to reflect complex biological functions. However, the design and fabrication of thes...
High-Strength, Durable All-Silk Fibroin Hydrogels with Versatile Processability toward Multifunctional Applications [0.03%]
高强度耐用全丝素水凝胶及其多功能应用的多种加工方式
Zhenghua Zhu,Shengjie Ling,Jingjie Yeo et al.
Zhenghua Zhu et al.
Hydrogels have been the focus of extensive research due to their potential use in fields including biomedical, pharmaceutical, biosensors, and cosmetics. However, the general weak mechanical properties of hydrogels limit their utility. Here...
Moldless Printing of Silicone Lenses With Embedded Nanostructured Optical Filters [0.03%]
无模具打印嵌有纳米结构光学滤波器的硅胶镜片
Stefano Mariani,Valentina Robbiano,Rossella Iglio et al.
Stefano Mariani et al.
Optical lenses are among the oldest technological innovations (3000 years ago) and they have enabled a multitude of applications in healthcare and in our daily lives. The primary function of optical lenses has changed little over time; they...
A Modular Vaccine Platform Combining Self-Assembled Peptide Cages and Immunogenic Peptides [0.03%]
一种模块化疫苗平台结合自组装肽笼和免疫原性肽
Caroline Morris,Sarah J Glennie,Hon S Lam et al.
Caroline Morris et al.
Subunit vaccines use delivery platforms to present minimal antigenic components for immunization. The benefits of such systems include multivalency, self-adjuvanting properties, and more specific immune responses. Previously, the design, sy...
Viromimetic STING Agonist-Loaded Hollow Polymeric Nanoparticles for Safe and Effective Vaccination against Middle East Respiratory Syndrome Coronavirus [0.03%]
用于安全有效预防中东呼吸综合征冠状病毒的模拟病毒载体STING激动剂空心聚合物纳米颗粒疫苗
Leon Chien-Wei Lin,Chen-Yu Huang,Bing-Yu Yao et al.
Leon Chien-Wei Lin et al.
The continued threat of emerging, highly lethal infectious pathogens such as Middle East respiratory syndrome coronavirus (MERS-CoV) calls for the development of novel vaccine technology that offers safe and effective prophylactic measures....
Host Cell Mimic Polymersomes for Rapid Detection of Highly Pathogenic Influenza Virus via a Viral Fusion and Cell Entry Mechanism [0.03%]
利用病毒融合和细胞摄取机制快速检测高致病性流感病毒的宿主细胞模拟聚合物囊泡
Hyun-Ouk Kim,Woonsung Na,Minjoo Yeom et al.
Hyun-Ouk Kim et al.
Highly pathogenic avian influenza virus (HPAIV) infections have occurred continuously and crossed the species barrier to humans, leading to fatalities. A polymerase chain reaction based molecular test is currently the most sensitive diagnos...
Enhanced Fluorescence for Bioassembly by Environment-Switching Doping of Metal Ions [0.03%]
通过金属离子环境切换掺杂促进生物组装的增强荧光效应
Kai Tao,Yu Chen,Asuka A Orr et al.
Kai Tao et al.
The self-assembly of cyclodipeptides composed of natural aromatic amino acids into supramolecular structures of diverse morphologies with intrinsic emissions in the visible light region is demonstrated. The assembly process can be halted at...
Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury [0.03%]
受血小板启发的纳米细胞在缺血/再灌注损伤后的心脏修复中的作用
Teng Su,Ke Huang,Hong Ma et al.
Teng Su et al.
Cardiovascular disease is the leading cause of mortality worldwide. While reperfusion therapy is vital for patient survival post-heart attack, it also causes further tissue injury, known as myocardial ischemia/reperfusion (I/R) injury in cl...