Stretchable Composite Acoustic Transducer for Wearable Monitoring of Vital Signs [0.03%]
用于穿戴生命体征监测的可拉伸复合声波换能器
Yasin Cotur,Michael Kasimatis,Matti Kaisti et al.
Yasin Cotur et al.
A highly flexible, stretchable, and mechanically robust low-cost soft composite consisting of silicone polymers and water (or hydrogels) is reported. When combined with conventional acoustic transducers, the materials reported enable high p...
Void-free 3D Bioprinting for In-situ Endothelialization and Microfluidic Perfusion [0.03%]
无空腔的3D生物打印用于原位内皮化和微流控灌注
Liliang Ouyang,James P K Armstrong,Qu Chen et al.
Liliang Ouyang et al.
Two major challenges of 3D bioprinting are the retention of structural fidelity and efficient endothelialization for tissue vascularization. We address both of these issues by introducing a versatile 3D bioprinting strategy, in which a temp...
Recent Advances in Smart Biomaterials for the Detection and Treatment of Autoimmune Diseases [0.03%]
用于自身免疫性疾病检测和治疗的智能生物材料的最新进展
Aaliyah B Shodeinde,Andrew C Murphy,Heidi F Oldenkamp et al.
Aaliyah B Shodeinde et al.
Autoimmune diseases are a group of debilitating illnesses that are often idiopathic in nature. The steady rise in the prevalence of these conditions warrants new approaches for diagnosis and treatment. Stimuli-responsive biomaterials also k...
A Patch of Detachable Hybrid Microneedle Depot for Localized Delivery of Mesenchymal Stem Cells in Regeneration Therapy [0.03%]
用于再生疗法中局部传递间充质干细胞的可脱落微针贴片
KangJu Lee,Yumeng Xue,Junmin Lee et al.
KangJu Lee et al.
Mesenchymal stem cells (MSCs) have been widely used for regenerative therapy. In most current clinical applications, MSCs are delivered by injection but face significant issues with cell viability and penetration into the target tissue due ...
Biodegradable nanofibrous temperature-responsive gelling microspheres for heart regeneration [0.03%]
用于心脏再生的生物可降解纳米纤维状温度响应性凝胶微球
Chao Zhao,Shuo Tian,Qihai Liu et al.
Chao Zhao et al.
Myocardial infarction (heart attack) is the number one killer of heart patients. Existing treatments for heart attack do not address the underlying problem of cardiomyocyte (CM) loss and cannot regenerate the myocardium. Introducing exogeno...
Poly(cyclodextrin)-Polydrug Nanocomplexes as Synthetic Oncolytic Virus for Locoregional Melanoma Chemoimmunotherapy [0.03%]
聚环糊精-多药纳米复合物作为合成的溶瘤病毒用于局部黑色素瘤的化疗免疫治疗
Jihoon Kim,Lauren F Sestito,Sooseok Im et al.
Jihoon Kim et al.
Despite the approval of oncolytic virus therapy for advanced melanoma, its intrinsic limitations that include the risk of persistent viral infection and cost-intensive manufacturing motivate the development of analogous approaches that are ...
A Collagen Based Cryogel Bioscaffold that Generates Oxygen for Islet Transplantation [0.03%]
用于胰岛移植可产生氧气的胶原基冷冻胶生物支架
Mehdi Razavi,Rosita Primavera,Bhavesh D Kevadiya et al.
Mehdi Razavi et al.
The aim of this work was to develop, characterize and test a novel 3D bioscaffold matrix which can accommodate pancreatic islets and provide them with a continuous, controlled and steady source of oxygen to prevent hypoxia-induced damage fo...
3D printing of a biocompatible double network elastomer with digital control of mechanical properties [0.03%]
具有机械性能数字控制的生物相容性双网络弹性体的3D打印技术
Pengrui Wang,David B Berry,Zhaoqiang Song et al.
Pengrui Wang et al.
The majority of 3D-printed biodegradable biomaterials are brittle, limiting their potential application to compliant tissues. Poly (glycerol sebacate) acrylate (PGSA) is a synthetic biodegradable and biocompatible elastomer, compatible with...
Nonmulberry Silk Based Ink for Fabricating Mechanically Robust Cardiac Patches and Endothelialized Myocardium-on-a-Chip Application [0.03%]
基于非桑蚕丝墨水的力学强化心脏贴片及内皮化类器官心脏应用研究
Shreya Mehrotra,Bruna A G de Melo,Minoru Hirano et al.
Shreya Mehrotra et al.
Bioprinting holds great promise towards engineering functional cardiac tissue constructs for regenerative medicine and as drug test models. However, it is highly limited by the choice of inks that require maintaining a balance between the s...
Inhibition of Immunosuppressive Tumors by Polymer-Assisted Inductions of Immunogenic Cell Death and Multivalent PD-L1 Crosslinking [0.03%]
通过聚合物介导的免疫原性细胞死亡和多价PD-L1交联诱导抑制免疫抑制肿瘤
Lian Li,Yachao Li,Chieh-Hsiang Yang et al.
Lian Li et al.
Checkpoint blockade immunotherapies harness the host's own immune system to fight cancer, but only work against tumors infiltrated by swarms of pre-existing T cells. Unfortunately, most cancers to date are immune-deserted. Here, we report a...