Recapitulating pancreatic tumor microenvironment through synergistic use of patient organoids and organ-on-a-chip vasculature [0.03%]
通过协同利用患者器官体和芯片血管再现胰腺肿瘤微环境
F L Lai Benjamin,X Lu Rick,Yangshuo Hu et al.
F L Lai Benjamin et al.
Tumor progression relies heavily on the interaction between the neoplastic epithelial cells and their surrounding stromal partners. This cell cross-talk affects stromal development, and ultimately the heterogeneity impacts drug efflux and e...
Cell derived extracellular matrix-rich biomimetic substrate supports podocyte proliferation, differentiation and maintenance of native phenotype [0.03%]
细胞来源的富含胞外基质的仿生底物支持足细胞增殖、分化及维持固有表型
Abhigyan Satyam,Maria G Tsokos,Jason S Tresback et al.
Abhigyan Satyam et al.
Current technologies and available scaffold materials do not support long-term cell viability, differentiation and maintenance of podocytes, the ultra-specialized kidney resident cells that are responsible for the filtration of the blood. W...
Bi-layered Tubular Microfiber Scaffolds as Functional Templates for Engineering Human Intestinal Smooth Muscle Tissue [0.03%]
双层管状微纤维支架作为工程人体肠平滑肌组织的功能模板
Ying Chen,Chengchen Guo,Eleana Manousiouthakis et al.
Ying Chen et al.
Designing biomimetic scaffolds with in vivo-like microenvironments using biomaterials is an essential component of successful tissue engineering approaches. The intestinal smooth muscle layers exhibit a complex tubular structure consisting ...
Multifunctional Artificial Artery from Direct 3D Printing with Built-In Ferroelectricity and Tissue-Matching Modulus for Real-Time Sensing and Occlusion Monitoring [0.03%]
具备内置铁电性和组织匹配刚度的直接三维打印多功能人造动脉用于实时监测和闭塞检测
Jun Li,Yin Long,Fan Yang et al.
Jun Li et al.
Treating vascular grafts failure requires complex surgery procedures and is associated with high risks. A real-time monitoring vascular system enables quick and reliable identification of complications and initiates safer treatments early. ...
3D Bioprinting using UNIversal Orthogonal Network (UNION) Bioinks [0.03%]
基于通用正交网络（UNION）生物墨水的3D 生物打印技术
Sarah M Hull,Christopher D Lindsay,Lucia G Brunel et al.
Sarah M Hull et al.
Three-dimensional (3D) bioprinting is a promising technology to produce tissue-like structures, but a lack of diversity in bioinks is a major limitation. Ideally each cell type would be printed in its own customizable bioink. To fulfill thi...
Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues [0.03%]
工程组织中功能性血管化的瞬时纤维母细胞支持机制
H-H Greco Song,Alex Lammers,Subramanian Sundaram et al.
H-H Greco Song et al.
Formation of capillary blood vasculature is a critical requirement for native as well as engineered organs and can be induced in vitro by co-culturing endothelial cells with fibroblasts. However, whether these fibroblasts are required only ...
So Yeon Ahn,Jin Liu,Srivithya Vellampatti et al.
So Yeon Ahn et al.
Due to its unique physical and chemical characteristics, DNA, which is known only as genetic information, has been identified and utilized as a new material at an astonishing rate. The role of DNA has increased dramatically with the advent ...
Copper@ZIF-8 Core-Shell Nanowires for Reusable Antimicrobial Face Masks [0.03%]
用于可重复使用的抗菌口罩的铜@ZIF-8核壳纳米线
Abhishek Kumar,Anu Sharma,Yi Chen et al.
Abhishek Kumar et al.
SARS-CoV-2 and other respiratory viruses spread via aerosols generated by infected people. Face masks can limit transmission. However, widespread use of disposable masks consumes tremendous resources and generates waste. Here, a novel mater...
Bita Nasiri,Sindhu Row,Randall J Smith Jr et al.
Bita Nasiri et al.
Cell-free small diameter vascular grafts, based on small intestinal submucosa (SIS) functionalized with heparin and vascular endothelial growth factor (VEGF) manufactured and implanted successfully into the arterial system of neonatal lambs...
An Ultraflexible and Stretchable Aptameric Graphene Nanosensor for Biomarker Detection and Monitoring [0.03%]
一种超柔韧和可拉伸的适配体石墨烯纳米传感器用于生物标志物的检测及监控
Ziran Wang,Zhuang Hao,Shifeng Yu et al.
Ziran Wang et al.
An ultraflexible and stretchable field-effect transistor nanosensor is presented that uses aptamer-functionalized monolayer graphene as the conducting channel. Specific binding of the aptamer with the target biomarker induces a change in th...