Engineered Spider Silk Proteins for Biomimetic Spinning of Fibers with Toughness Equal to Dragline Silks [0.03%]
用于生物模拟纺丝的工程蜘蛛丝蛋白，其韧性可与拖曳丝相媲美
Tina Arndt,Gabriele Greco,Benjamin Schmuck et al.
Tina Arndt et al.
Spider silk is the toughest fiber found in nature, and bulk production of artificial spider silk that matches its mechanical properties remains elusive. Development of miniature spider silk proteins (mini-spidroins) has made large-scale fib...
Synovial fluid pH sensor for early detection of prosthetic hip infections [0.03%]
用于早期发现髋关节假体感染的滑液pH值传感器
Uthpala Wijayaratna,Sachindra Kiridena,John D Adams et al.
Uthpala Wijayaratna et al.
We describe an implantable sensor developed to measure synovial fluid pH for noninvasive early detection and monitoring of hip infections using standard-of-care plain radiography. The sensor was made of a pH responsive polyacrylic acid-base...
Scalable Thousand Channel Penetrating Microneedle Arrays on Flex for Multimodal and Large Area Coverage BrainMachine Interfaces [0.03%]
用于多模态和大范围脑机接口的可扩展千通道穿透式微针阵列
Sang Heon Lee,Martin Thunemann,Keundong Lee et al.
Sang Heon Lee et al.
The Utah array powers cutting-edge projects for restoration of neurological function, such as BrainGate, but the underlying electrode technology has itself advanced little in the last three decades. Here, advanced dual-side lithographic mic...
On-Demand Chemomagnetic Modulation of Striatal Neurons Facilitated by Hybrid Magnetic Nanoparticles [0.03%]
磁杂化纳米颗粒介导的纹状体神经元化学磁调节对需求型治疗的影响研究
Rohini Thevi Guntnur,Nicolas Muzzio,Amanda Gomez et al.
Rohini Thevi Guntnur et al.
Minimally invasive manipulation of cell signaling is critical in basic neuroscience research and in developing therapies for neurological disorders. Here, we describe a wireless chemomagnetic neuromodulation platform for the on-demand contr...
Ryan Dubay,Joseph N Urban,Eric M Darling
Ryan Dubay
Cell encapsulation within hydrogel droplets is transforming what is feasible in multiple fields of biomedical science such as tissue engineering and regenerative medicine, in vitro modeling, and cell-based therapies. Recent advances have al...
Md Azahar Ali,Chunshan Hu,Eric A Yttri et al.
Md Azahar Ali et al.
Additive manufacturing, also called 3D printing, is a rapidly evolving technique that allows for the fabrication of functional materials with complex architectures, controlled microstructures, and material combinations. This capability has ...
Wirelessly Powered 3D Printed Hierarchical Biohybrid Robots with Multiscale Mechanical Properties [0.03%]
具有多尺度力学性能的无线供电分层生物混合机器人Printing
Hiroyuki Tetsuka,Lorenzo Pirrami,Ting Wang et al.
Hiroyuki Tetsuka et al.
The integration of flexible and stretchable electronics into biohybrid soft robotics can spur the development of new approaches to fabricate biohybrid soft machines, thus enabling a wide variety of innovative applications. Inspired by flexi...
Engineering the human blood-brain barrier at the capillary scale using a double-templating technique [0.03%]
一种双模板技术在毛细管尺度上工程化构建人类血脑屏障的方法研究
Nan Zhao,Zhaobin Guo,Sarah Kulkarni et al.
Nan Zhao et al.
In vitro blood-brain barrier (BBB) models have played an important role in studying processes such as immune cell trafficking and drug delivery, as well as contributing to the understanding of mechanisms of disease progression. Many biologi...
Harnessing DNA for immunotherapy: Cancer, infectious diseases, and beyond [0.03%]
利用DNA进行免疫治疗：癌症、传染病等领域的应用和发展
Yixin Wang,Ting-Jing Chen-Mayfield,Zhaoting Li et al.
Yixin Wang et al.
Despite the rapid development of immunotherapy, low response rates, poor therapeutic outcomes and severe side effects still limit their implementation, making the augmentation of immunotherapy an important goal for current research. DNA, wh...
2D Zn-Porphyrin-Based Co(II)-MOF with 2-Methylimidazole Sitting Axially on the Paddle-Wheel Units: An Efficient Electrochemiluminescence Bioassay for SARS-CoV-2 [0.03%]
以2-甲基咪唑轴向配位的二维Zn-卟啉基Co(II)-MOF：一种高效电化学发光生物检测SARS-CoV-2的方法
Yi-Xuan Li,Jing Li,Dunru Zhu et al.
Yi-Xuan Li et al.
High electrocatalytic activity with tunable luminescence is crucial for the development of electrochemiluminescence (ECL) luminophores. In this study, a porphyrin-based heterobimetallic 2D metal organic framework (MOF), [(ZnTCPP)Co2(MeIm)] ...