Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC-MS [0.03%]
利用交联和尺寸排阻质谱法识别大肠杆菌的胞内组分
Rachel A Victor,Austin Lipinski,Paul R Langlais et al.
Rachel A Victor et al.
Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are lim...
Quantitative Proteomics Reveals the Adaptive Mechanisms of Aeromonas hydrophila Under Cobalt Stress [0.03%]
定量蛋白质组学揭示了霍里蒙菌在钴胁迫下的适应机制
Xiaowei Zhang,Chenghao Shen,Zhen Qiu et al.
Xiaowei Zhang et al.
Cobalt is an essential micronutrient but becomes toxic at elevated concentrations, requiring microorganisms to balance acquisition and detoxification. Aeromonas hydrophila, an opportunistic aquatic pathogen, is often encountered in metal-co...
Aivett Bilbao,Tim Causon
Aivett Bilbao
Proteomic and Lipidomic Profiling of Immune Cell-Derived Subpopulations of Extracellular Vesicles [0.03%]
免疫细胞源外泌体亚群的蛋白质组和脂质组分析
Anna Lischnig,Nasibeh Karimi,Per Larsson et al.
Anna Lischnig et al.
Extracellular vesicles (EVs) are heterogeneous and play important roles in intercellular communication, contributing to physiological and pathological processes. Since few markers currently exist to differentiate subtypes of EVs, this study...
Brownotate, a Comprehensive Solution to Generate Protein Sequence Databases for Any Species [0.03%]
Brownotate：一种全面的生成任何物种蛋白质序列数据库的方法
Adrien Brown,Alexandre Burel,Sarah Cianférani et al.
Adrien Brown et al.
Proteomics is strengthening research in biology and the diversification of the model organisms studied is very promising for fully understanding the complexity of biological principles. However, the lack of protein sequence databases for ma...
Proteomics in Practice: A Case Study Highlighting Tandem Mass Tag-Based MS for Quantitative Profiling of Extracellular Vesicles and Application to Irradiated Fibroblasts [0.03%]
定量分析辐射诱导的成纤维细胞来源的外泌体的蛋白质组学研究
Greg Berumen Sánchez,Purvi Patel,Kristie Lindsey Rose et al.
Greg Berumen Sánchez et al.
Extracellular vesicles (EVs) are critical mediators of intercellular communication, and valuable sources of biomarkers for diagnostic and therapeutic applications. However, the complexity and heterogeneity of EVs present significant challen...
Assessing Discrepancies in miRNA Profiles of Mouse Blood-Derived Extracellular Vesicles: A Systematic Review of Sequencing Data [0.03%]
基于小鼠血液来源外泌体的系统评价：对miRNA谱系差异的序列表达数据分析综述研究
Md Sorwer Alam Parvez,Erika Hayakawa,Yoritsugu Iida et al.
Md Sorwer Alam Parvez et al.
We systematically reviewed published studies to assess reproducibility in miRNA expression profiles from extracellular vesicles (EVs) isolated from mouse serum. Our search specifically targeted mouse studies employing precipitation methods ...
Proteome-Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling [0.03%]
泛素化蛋白质组学揭示了免疫早期信号传导的新见解
Hyojung Kim,Jiraphorn Issara-Amphorn,Sung Hwan Yoon et al.
Hyojung Kim et al.
Protein S-palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains...
Xiaorui Cheng,Haixia Wu,Pengji Chen et al.
Xiaorui Cheng et al.
CD8+ T-cell epitopes are special peptide fragments produced by the catabolism of antigenic proteins. After being presented on the surface of antigen-presenting cells in association with Major Histocompatibility Complex-I (MHC-I) molecules, ...
Performance Characteristics of Zeno Trap Scanning DIA for Sensitive and Quantitative Proteomics at High Throughput [0.03%]
高通量敏感定量蛋白质组学的Zeno阱扫描DIA性能特征分析
Ludwig R Sinn,Ziyue Wang,Claudia P Alvarez et al.
Ludwig R Sinn et al.
Proteomic experiments, particularly those addressing dynamic proteome properties, time series, or genetic diversity, require the analysis of large sample numbers. Despite significant advancements in proteomic technologies in recent years, f...