Quantifying and modeling loss of estrogen and progesterone in PDMS-based devices [0.03%]
基于PDMS器件中雌激素和孕酮的损失量化与建模
Nathaniel G Hermann,Richard A Ficek,Dmitry A Markov et al.
Nathaniel G Hermann et al.
An early study on the biological consequences of using polydimethysiloxane (PDMS) for microfluidic cell culture reported that estrogens could be sequestered by PDMS; however, the PDMS interaction parameters of specific hormones have not bee...
High throughput cell mechanotyping of cell response to cytoskeletal modulations using a microfluidic cell deformation system [0.03%]
利用微流体细胞变形系统进行细胞骨架调制的高通量细胞力学分型研究
Ian M Smith,Jeanine A Ursitti,Sai Pranav Majeti Venkata et al.
Ian M Smith et al.
Cellular mechanical properties influence cellular functions across pathological and physiological systems. The observation of these mechanical properties is limited in part by methods with a low throughput of acquisition or with low accessi...
Using dimensionless numbers to understand interfacial mass transfer for parallel flow in a microchannel [0.03%]
利用无量纲数理解微通道并流下的界面传质问题
Anand Sudha,Martin Rohde
Anand Sudha
Liquid-liquid Extraction has emerged as a major technique for radioisotope extraction in recent years. This technique is particularly advantageous in the microscale as the surface-volume ratio is much larger. Since some of these radioisotop...
Modelling, simulation, and experimental characterization of particle sedimentation inside a horizontal syringe [0.03%]
水平注射器内颗粒沉降的建模、仿真及实验表征
Maryamsadat Ghoreishi,Efsun Senturk,Gianluca Cidonio et al.
Maryamsadat Ghoreishi et al.
Sedimentation is the settling of solid particles in a liquid medium driven by gravity. This phenomenon poses significant challenges in experimental lab-on-chip (LOC) applications, as they often involve a biological sample to be loaded insid...
Lab on a chip for detecting Clara cell protein 16 (CC16) for potential screening of the workers exposed to respirable silica aerosol [0.03%]
用于检测克拉拉细胞蛋白16 (CC16)的芯片实验室，有望筛查暴露于可吸入硅尘气溶胶的工人
Chong Ahn,Taekhee Lee,Jae Hoon Shin et al.
Chong Ahn et al.
Early detection of pulmonary responses to silica aerosol exposure, such as lung inflammation as well as early identification of silicosis initiation, is of great importance in disease prevention of workers. In this study, to early screen th...
Microfluidic Continuous Flow DNA Fragmentation based on a Vibrating Sharp-tip [0.03%]
基于振动尖端的微流控连续流DNA片段化
Xiaojun Li,Jing Wang,Kathrine Curtin et al.
Xiaojun Li et al.
Fragmentation of DNA into short fragments is of great importance for detecting and studying DNAs. Current microfluidic methods of DNA fragmentation are either inefficient for generating small fragments or rely on microbubbles. Here, we repo...
Maximizing flow rate in single paper layer, rapid flow microfluidic paper-based analytical devices [0.03%]
基于纸层析的分析设备中单层纸的最大流速研究
Iain Macleod Briongos,Zachary D Call,Charles S Henry et al.
Iain Macleod Briongos et al.
Small, single-layer microfluidic paper-based analytical devices (µPADs) offer potential for a range of point-of-care applications; however, they have been limited to low flow rates. Here, we investigate the role of laser cutting paper chan...
Cheng Bai,Xin Meng,Kechun Wen et al.
Cheng Bai et al.
Aptamers are synthetic single-stranded nucleic acid molecules that bind to biochemical targets with high affinity and specificity. The method of systematic evolution of ligands by exponential enrichment (SELEX) is widely used to isolate apt...
Abhishek Futane,Vigneswaran Narayanamurthy,Pramod Jadhav et al.
Abhishek Futane et al.
Aptasensors have attracted considerable interest and widespread application in point-of-care testing worldwide. One of the biggest challenges of a point-of-care (POC) is the reduction of treatment time compared to central facilities that di...
Fabrication of microtiter plate on paper using 96-well plates for wax stamping [0.03%]
利用96孔板制作纸基微孔板蜡模板的方法
Madhurima Borah,Diksha Maheswari,Hemant Sankar Dutta
Madhurima Borah
Paper-based analytical devices have prominently emerged as a group of diagnostic tools with prospective to eliminate the expensive, time-consuming, and intricate analytical methodologies. Wax printing has been a dominant technique to fabric...