Davide Spalvieri,Anne-Marine Mauviel,Matthieu Lambert et al.
Davide Spalvieri et al.
We discuss how design enriches molecular science, particularly structural biology and bioinformatics. We present two use cases, one in academic practice and the other to design for outreach. The first case targets the representation of ion ...
David S Goodsell
David S Goodsell
Data from genomics, proteomics, structural biology and cryo-electron microscopy are integrated into a structural illustration of a cross section through an entire JCVI-syn3.0 minimal cell. The illustration is designed with several goals: to...
Laura Garrison,Stefan Bruckner
Laura Garrison
Biomedical illustration and visualization techniques provide a window into complex molecular worlds that are difficult to capture through experimental means alone. Biomedical illustrators frequently employ color to help tell a molecular sto...
Integrative analysis of chemical properties and functions of drugs for adverse drug reaction prediction based on multi-label deep neural network [0.03%]
基于多标签深度神经网络的药物化学性质和功能整合分析及其不良反应预测研究
Pranab Das,Yogita,Vipin Pal
Pranab Das
The prediction of adverse drug reactions (ADR) is an important step of drug discovery and design process. Different drug properties have been employed for ADR prediction but the prediction capability of drug properties and drug functions in...
Genome-wide expression reveals potential biomarkers in breast cancer bone metastasis [0.03%]
基因组表达揭示乳腺癌骨转移的潜在生物标志物
Yashbir Singh,Naidu Subbarao,Abhinav Jaimini et al.
Yashbir Singh et al.
Breast cancer metastases are most commonly found in bone, an indication of poor prognosis. Pathway-based biomarkers identification may help elucidate the cellular signature of breast cancer metastasis in bone, further characterizing the eti...
A review on methods for predicting miRNA-mRNA regulatory modules [0.03%]
预测微小核糖核酸-信使核糖核酸调控模块方法的研究进展综述
Madhumita Madhumita,Sushmita Paul
Madhumita Madhumita
Identification of complex interactions between miRNAs and mRNAs in a regulatory network helps better understand the underlying biological processes. Previously, identification of these interactions was based on sequence-based predicted targ...
The simulation experiment description markup language (SED-ML): language specification for level 1 version 4 [0.03%]
模拟实验描述标记语言（SED-ML）：第1版第4次修订的语言规范
Lucian P Smith,Frank T Bergmann,Alan Garny et al.
Lucian P Smith et al.
Computational simulation experiments increasingly inform modern biological research, and bring with them the need to provide ways to annotate, archive, share and reproduce the experiments performed. These simulations increasingly require ex...
Franziska Reinhardt,Peter F Stadler
Franziska Reinhardt
Spliced alignments are a key step in the construction of high-quality homology-based annotations of protein sequences. The exon/intron structure, which is computed as part of spliced alignment procedures, often conveys important information...
A systematic study of motif pairs that may facilitate enhancer-promoter interactions [0.03%]
系统研究可能促进增强子-启动子相互作用的基序对
Saidi Wang,Haiyan Hu,Xiaoman Li
Saidi Wang
Pairs of interacting transcription factors (TFs) have previously been shown to bind to enhancers and promoters and contribute to their physical interactions. However, to date, we have limited knowledge about such TF pairs. To fill this void...
Balázs Szalkai,Vince Grolmusz
Balázs Szalkai
The analysis of enormous datasets with missing data entries is a standard task in biological and medical data processing. Large-scale, multi-institution clinical studies are the typical examples of such datasets. These sets make possible th...