Co-creation environment with cloud virtual reality and real-time artificial intelligence toward the design of molecular robots [0.03%]
基于云虚拟现实和实时人工智能的分子机器人设计共创新环境
Akihiko Konagaya,Gregory Gutmann,Yuhui Zhang
Akihiko Konagaya
This paper describes the design philosophy for our cloud-based virtual reality (VR) co-creation environment (CCE) for molecular modeling. Using interactive VR simulation can provide enhanced perspectives in molecular modeling for intuitive ...
In silico studies of natural product-like caffeine derivatives as potential MAO-B inhibitors/AA2AR antagonists for the treatment of Parkinson's disease [0.03%]
计算研究咖啡因类似物作为治疗帕金森病的单胺氧化酶B抑制剂/5-HT2A受体拮抗剂的潜力
Yassir Boulaamane,Mahmoud A A Ibrahim,Mohammed Reda Britel et al.
Yassir Boulaamane et al.
Parkinson's disease is considered the second most frequent neurodegenerative disease. It is described by the loss of dopaminergic neurons in the mid-brain. For many decades, L-DOPA has been considered as the gold standard for treating Parki...
Bridging data management platforms and visualization tools to enable ad-hoc and smart analytics in life sciences [0.03%]
打通数据管理平台与可视化工具，实现生命科学领域的即席和智能分析
Christian Panse,Christian Trachsel,Can Türker
Christian Panse
Core facilities have to offer technologies that best serve the needs of their users and provide them a competitive advantage in research. They have to set up and maintain instruments in the range of ten to a hundred, which produce large amo...
Manuel Feser,Patrick König,Anne Fiebig et al.
Manuel Feser et al.
Over the last years it has been observed that the progress in data collection in life science has created increasing demand and opportunities for advanced bioinformatics. This includes data management as well as the individual data analysis...
Systematic assessment of template-based genome-scale metabolic models created with the BiGG Integration Tool [0.03%]
系统评估使用BiGG整合工具创建的基于模板的基因组规模代谢模型
Alexandre Oliveira,Emanuel Cunha,Fernando Cruz et al.
Alexandre Oliveira et al.
Genome-scale metabolic models (GEMs) are essential tools for in silico phenotype prediction and strain optimisation. The most straightforward GEMs reconstruction approach uses published models as templates to generate the initial draft, req...
Federated machine learning for a facilitated implementation of Artificial Intelligence in healthcare - a proof of concept study for the prediction of coronary artery calcification scores [0.03%]
面向医疗保健的人工智能的联邦机器学习实现方案的概念验证研究——冠状动脉钙化评分预测案例
Justus Wolff,Julian Matschinske,Dietrich Baumgart et al.
Justus Wolff et al.
The implementation of Artificial Intelligence (AI) still faces significant hurdles and one key factor is the access to data. One approach that could support that is federated machine learning (FL) since it allows for privacy preserving data...
Pierpaolo Vittorini,Pablo Chamoso,Fernando De la Prieta
Pierpaolo Vittorini
Tinnitus is an annoying ringing in the ears, in varying shades and intensities. Tinnitus can affect a person's overall health and social well-being (e.g., sleep problems, trouble concentrating, anxiety, depression and inability to work). Th...
KaIDA: a modular tool for assisting image annotation in deep learning [0.03%]
KaIDA：一种用于深度学习图像注释的模块化工具
Marcel P Schilling,Svenja Schmelzer,Lukas Klinger et al.
Marcel P Schilling et al.
Deep learning models achieve high-quality results in image processing. However, to robustly optimize parameters of deep neural networks, large annotated datasets are needed. Image annotation is often performed manually by experts without a ...
Evaluating molecular representations in machine learning models for drug response prediction and interpretability [0.03%]
评估机器学习模型中分子表征在药物反应预测和可解释性方面的表现
Delora Baptista,João Correia,Bruno Pereira et al.
Delora Baptista et al.
Machine learning (ML) is increasingly being used to guide drug discovery processes. When applying ML approaches to chemical datasets, molecular descriptors and fingerprints are typically used to represent compounds as numerical vectors. How...
Design X Bioinformatics: a community-driven initiative to connect bioinformatics and design [0.03%]
设计X生物信息学：一个连接生物信息学和设计的社区驱动倡议
Björn Sommer,Daisuke Inoue,Marc Baaden
Björn Sommer
Bioinformatics applies computer science approaches to the analysis of biological data. It is widely known for its genomics-based analysis approaches that have supported, for example, the 1000 Genomes Project. In addition, bioinformatics rel...